JPS57150668A - Novel 4-aroylimidazole-2-ones - Google Patents

Novel 4-aroylimidazole-2-ones

Info

Publication number
JPS57150668A
JPS57150668A JP57022154A JP2215482A JPS57150668A JP S57150668 A JPS57150668 A JP S57150668A JP 57022154 A JP57022154 A JP 57022154A JP 2215482 A JP2215482 A JP 2215482A JP S57150668 A JPS57150668 A JP S57150668A
Authority
JP
Japan
Prior art keywords
alkyl
ones
novel
piperazino
hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP57022154A
Other languages
English (en)
Other versions
JPH048421B2 (ja
Inventor
Ee Shiyunetsutoraa Richiyaado
Shii Deeji Richiyaado
Maachin Gurisaa Jiei
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Merrell Dow Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharmaceuticals Inc filed Critical Merrell Dow Pharmaceuticals Inc
Publication of JPS57150668A publication Critical patent/JPS57150668A/ja
Publication of JPH048421B2 publication Critical patent/JPH048421B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
JP57022154A 1981-02-18 1982-02-16 Novel 4-aroylimidazole-2-ones Granted JPS57150668A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23545381A 1981-02-18 1981-02-18

Publications (2)

Publication Number Publication Date
JPS57150668A true JPS57150668A (en) 1982-09-17
JPH048421B2 JPH048421B2 (ja) 1992-02-17

Family

ID=22885573

Family Applications (1)

Application Number Title Priority Date Filing Date
JP57022154A Granted JPS57150668A (en) 1981-02-18 1982-02-16 Novel 4-aroylimidazole-2-ones

Country Status (18)

Country Link
EP (1) EP0058435B1 (ja)
JP (1) JPS57150668A (ja)
KR (1) KR860001338B1 (ja)
AT (1) ATE24496T1 (ja)
AU (1) AU558789B2 (ja)
CA (1) CA1173047A (ja)
DE (1) DE3274855D1 (ja)
DK (1) DK161250C (ja)
ES (1) ES8307002A1 (ja)
GB (1) GB2093031B (ja)
GR (1) GR76025B (ja)
HK (1) HK61586A (ja)
IE (1) IE52422B1 (ja)
IL (1) IL65010A0 (ja)
MY (1) MY8600710A (ja)
NZ (1) NZ199733A (ja)
PH (1) PH18106A (ja)
ZA (1) ZA82969B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
ZA826501B (en) * 1982-09-06 1984-04-25 Du Pont Anti-hypertensive imidazole derivative
US4552880A (en) * 1983-02-15 1985-11-12 Merrell Dow Pharmaceuticals Inc. Aroylimidazolones
US4556665A (en) * 1984-07-09 1985-12-03 Schering A.G. Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
EP1737447A1 (en) * 2004-03-22 2007-01-03 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
CA2560528A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (s) - enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS565463A (en) * 1979-06-18 1981-01-20 Richardson Merrell Inc Novel 44aroylimidazolee22ones

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS565463A (en) * 1979-06-18 1981-01-20 Richardson Merrell Inc Novel 44aroylimidazolee22ones

Also Published As

Publication number Publication date
NZ199733A (en) 1985-05-31
ZA82969B (en) 1983-09-28
PH18106A (en) 1985-03-21
GR76025B (ja) 1984-08-03
AU8048682A (en) 1982-08-26
DK161250B (da) 1991-06-17
IE820333L (en) 1982-08-18
IL65010A0 (en) 1982-04-30
ES509636A0 (es) 1983-07-01
ATE24496T1 (de) 1987-01-15
DK161250C (da) 1991-12-09
GB2093031A (en) 1982-08-25
EP0058435B1 (en) 1986-12-30
JPH048421B2 (ja) 1992-02-17
IE52422B1 (en) 1987-10-28
KR860001338B1 (ko) 1986-09-15
GB2093031B (en) 1984-10-24
ES8307002A1 (es) 1983-07-01
EP0058435A3 (en) 1984-03-21
AU558789B2 (en) 1987-02-12
KR830009045A (ko) 1983-12-17
DE3274855D1 (de) 1987-02-05
EP0058435A2 (en) 1982-08-25
CA1173047A (en) 1984-08-21
MY8600710A (en) 1986-12-31
HK61586A (en) 1986-08-29
DK67582A (da) 1982-08-19

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