ZA82969B - Novel 4-aroylimidazol-2-ones - Google Patents

Novel 4-aroylimidazol-2-ones

Info

Publication number
ZA82969B
ZA82969B ZA82969A ZA82969A ZA82969B ZA 82969 B ZA82969 B ZA 82969B ZA 82969 A ZA82969 A ZA 82969A ZA 82969 A ZA82969 A ZA 82969A ZA 82969 B ZA82969 B ZA 82969B
Authority
ZA
South Africa
Prior art keywords
alkyl
aroylimidazol
ones
novel
piperazino
Prior art date
Application number
ZA82969A
Other languages
English (en)
Inventor
Richard A Schnettler
Richard C Dage
Grisar J Martin
J Martin Grisar
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA82969B publication Critical patent/ZA82969B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70—One oxygen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA82969A 1981-02-18 1982-02-15 Novel 4-aroylimidazol-2-ones ZA82969B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US23545381A 1981-02-18 1981-02-18

Publications (1)

Publication Number Publication Date
ZA82969B true ZA82969B (en) 1983-09-28

Family

ID=22885573

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA82969A ZA82969B (en) 1981-02-18 1982-02-15 Novel 4-aroylimidazol-2-ones

Country Status (18)

Country Link
EP (1) EP0058435B1 (ja)
JP (1) JPS57150668A (ja)
KR (1) KR860001338B1 (ja)
AT (1) ATE24496T1 (ja)
AU (1) AU558789B2 (ja)
CA (1) CA1173047A (ja)
DE (1) DE3274855D1 (ja)
DK (1) DK161250C (ja)
ES (1) ES509636A0 (ja)
GB (1) GB2093031B (ja)
GR (1) GR76025B (ja)
HK (1) HK61586A (ja)
IE (1) IE52422B1 (ja)
IL (1) IL65010A0 (ja)
MY (1) MY8600710A (ja)
NZ (1) NZ199733A (ja)
PH (1) PH18106A (ja)
ZA (1) ZA82969B (ja)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
ZA826501B (en) * 1982-09-06 1984-04-25 Du Pont Anti-hypertensive imidazole derivative
US4552880A (en) * 1983-02-15 1985-11-12 Merrell Dow Pharmaceuticals Inc. Aroylimidazolones
US4556665A (en) * 1984-07-09 1985-12-03 Schering A.G. Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
WO2005092333A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US20060025463A1 (en) * 2004-03-22 2006-02-02 Michael Bristow Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA803332B (en) * 1979-06-18 1981-01-28 Richardson Merrell Inc Novel 4-aroylimidazol-2-ones
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Also Published As

Publication number Publication date
DK161250C (da) 1991-12-09
GR76025B (ja) 1984-08-03
ATE24496T1 (de) 1987-01-15
KR830009045A (ko) 1983-12-17
KR860001338B1 (ko) 1986-09-15
MY8600710A (en) 1986-12-31
DK67582A (da) 1982-08-19
JPH048421B2 (ja) 1992-02-17
ES8307002A1 (es) 1983-07-01
IE820333L (en) 1982-08-18
IL65010A0 (en) 1982-04-30
EP0058435A3 (en) 1984-03-21
EP0058435B1 (en) 1986-12-30
AU8048682A (en) 1982-08-26
GB2093031B (en) 1984-10-24
EP0058435A2 (en) 1982-08-25
PH18106A (en) 1985-03-21
GB2093031A (en) 1982-08-25
DE3274855D1 (de) 1987-02-05
AU558789B2 (en) 1987-02-12
JPS57150668A (en) 1982-09-17
IE52422B1 (en) 1987-10-28
CA1173047A (en) 1984-08-21
NZ199733A (en) 1985-05-31
HK61586A (en) 1986-08-29
DK161250B (da) 1991-06-17
ES509636A0 (es) 1983-07-01

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