ATE24496T1 - 4-aroylimidazol-2-one. - Google Patents

4-aroylimidazol-2-one.

Info

Publication number
ATE24496T1
ATE24496T1 AT82101233T AT82101233T ATE24496T1 AT E24496 T1 ATE24496 T1 AT E24496T1 AT 82101233 T AT82101233 T AT 82101233T AT 82101233 T AT82101233 T AT 82101233T AT E24496 T1 ATE24496 T1 AT E24496T1
Authority
AT
Austria
Prior art keywords
alkyl
piperazino
hydrogen
aroylimidazole
alkylsufone
Prior art date
Application number
AT82101233T
Other languages
English (en)
Inventor
Richard A Schnettler
Richard C Dage
Martin J Grisar
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Application granted granted Critical
Publication of ATE24496T1 publication Critical patent/ATE24496T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Luminescent Compositions (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT82101233T 1981-02-18 1982-02-18 4-aroylimidazol-2-one. ATE24496T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23545381A 1981-02-18 1981-02-18
EP82101233A EP0058435B1 (de) 1981-02-18 1982-02-18 4-Aroylimidazol-2-one

Publications (1)

Publication Number Publication Date
ATE24496T1 true ATE24496T1 (de) 1987-01-15

Family

ID=22885573

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82101233T ATE24496T1 (de) 1981-02-18 1982-02-18 4-aroylimidazol-2-one.

Country Status (18)

Country Link
EP (1) EP0058435B1 (de)
JP (1) JPS57150668A (de)
KR (1) KR860001338B1 (de)
AT (1) ATE24496T1 (de)
AU (1) AU558789B2 (de)
CA (1) CA1173047A (de)
DE (1) DE3274855D1 (de)
DK (1) DK161250C (de)
ES (1) ES509636A0 (de)
GB (1) GB2093031B (de)
GR (1) GR76025B (de)
HK (1) HK61586A (de)
IE (1) IE52422B1 (de)
IL (1) IL65010A0 (de)
MY (1) MY8600710A (de)
NZ (1) NZ199733A (de)
PH (1) PH18106A (de)
ZA (1) ZA82969B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
ZA826501B (en) * 1982-09-06 1984-04-25 Du Pont Anti-hypertensive imidazole derivative
US4552880A (en) * 1983-02-15 1985-11-12 Merrell Dow Pharmaceuticals Inc. Aroylimidazolones
US4556665A (en) * 1984-07-09 1985-12-03 Schering A.G. Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
CA2560538A1 (en) * 2004-03-22 2005-10-06 Myogen, Inc. (r)-enoximone sulfoxide and its use in the treatment of pde-iii mediated diseases
US20060025463A1 (en) * 2004-03-22 2006-02-02 Michael Bristow Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA803332B (en) * 1979-06-18 1981-01-28 Richardson Merrell Inc Novel 4-aroylimidazol-2-ones
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions

Also Published As

Publication number Publication date
MY8600710A (en) 1986-12-31
KR860001338B1 (ko) 1986-09-15
DK67582A (da) 1982-08-19
IL65010A0 (en) 1982-04-30
GR76025B (de) 1984-08-03
CA1173047A (en) 1984-08-21
DK161250C (da) 1991-12-09
ES8307002A1 (es) 1983-07-01
AU8048682A (en) 1982-08-26
DK161250B (da) 1991-06-17
EP0058435A3 (en) 1984-03-21
GB2093031B (en) 1984-10-24
HK61586A (en) 1986-08-29
ZA82969B (en) 1983-09-28
ES509636A0 (es) 1983-07-01
EP0058435B1 (de) 1986-12-30
AU558789B2 (en) 1987-02-12
DE3274855D1 (de) 1987-02-05
IE820333L (en) 1982-08-18
IE52422B1 (en) 1987-10-28
JPS57150668A (en) 1982-09-17
NZ199733A (en) 1985-05-31
PH18106A (en) 1985-03-21
EP0058435A2 (de) 1982-08-25
KR830009045A (ko) 1983-12-17
JPH048421B2 (de) 1992-02-17
GB2093031A (en) 1982-08-25

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time