DK67582A - Fremgangsmaade til fremstilling af aroylimidazol-2-oner - Google Patents

Fremgangsmaade til fremstilling af aroylimidazol-2-oner Download PDF

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Publication number
DK67582A
DK67582A DK67582A DK67582A DK67582A DK 67582 A DK67582 A DK 67582A DK 67582 A DK67582 A DK 67582A DK 67582 A DK67582 A DK 67582A DK 67582 A DK67582 A DK 67582A
Authority
DK
Denmark
Prior art keywords
alkyl
aroylimidazole
oner
preparing
procedure
Prior art date
Application number
DK67582A
Other languages
English (en)
Other versions
DK161250C (da
DK161250B (da
Inventor
R A Schnettler
R C Dage
J M Grisar
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of DK67582A publication Critical patent/DK67582A/da
Publication of DK161250B publication Critical patent/DK161250B/da
Application granted granted Critical
Publication of DK161250C publication Critical patent/DK161250C/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/70One oxygen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Luminescent Compositions (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Cephalosporin Compounds (AREA)
DK067582A 1981-02-18 1982-02-16 Analogifremgangsmaade til fremstilling af 4-aroyl-imidazol-2-oner eller pharmaceutisk acceptable salte deraf DK161250C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23545381A 1981-02-18 1981-02-18
US23545381 1981-02-18

Publications (3)

Publication Number Publication Date
DK67582A true DK67582A (da) 1982-08-19
DK161250B DK161250B (da) 1991-06-17
DK161250C DK161250C (da) 1991-12-09

Family

ID=22885573

Family Applications (1)

Application Number Title Priority Date Filing Date
DK067582A DK161250C (da) 1981-02-18 1982-02-16 Analogifremgangsmaade til fremstilling af 4-aroyl-imidazol-2-oner eller pharmaceutisk acceptable salte deraf

Country Status (18)

Country Link
EP (1) EP0058435B1 (da)
JP (1) JPS57150668A (da)
KR (1) KR860001338B1 (da)
AT (1) ATE24496T1 (da)
AU (1) AU558789B2 (da)
CA (1) CA1173047A (da)
DE (1) DE3274855D1 (da)
DK (1) DK161250C (da)
ES (1) ES8307002A1 (da)
GB (1) GB2093031B (da)
GR (1) GR76025B (da)
HK (1) HK61586A (da)
IE (1) IE52422B1 (da)
IL (1) IL65010A0 (da)
MY (1) MY8600710A (da)
NZ (1) NZ199733A (da)
PH (1) PH18106A (da)
ZA (1) ZA82969B (da)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4405628A (en) * 1981-03-05 1983-09-20 Merrell Dow Pharmaceuticals Inc. 4-Pyridylimidazolones and method of use
US4410540A (en) * 1981-11-04 1983-10-18 Merrell Dow Pharmaceuticals Inc. Cardiotonic 4-aroylimidazolidin-2-ones
US4367236A (en) * 1981-11-04 1983-01-04 Merrell Dow Pharmaceuticals Inc. Method for the treatment of cardiac failure with alkanoylimidazol-2-one derivatives
ZA826501B (en) * 1982-09-06 1984-04-25 Du Pont Anti-hypertensive imidazole derivative
US4552880A (en) * 1983-02-15 1985-11-12 Merrell Dow Pharmaceuticals Inc. Aroylimidazolones
US4556665A (en) * 1984-07-09 1985-12-03 Schering A.G. Cardiotonic 1,3-dihydro-4-[[(imidazol-1-yl)aryl]carbonyl]imidazol-2-ones
US20060030611A1 (en) * 2004-03-22 2006-02-09 Myogen, Inc. Enoximone sulfoxide enantiomers and their use in the treatment of PDE-III mediated diseases
JP2007530563A (ja) * 2004-03-22 2007-11-01 ミオゲン インコーポレイティッド (s)−エノキシモンスルホキシドおよびpde−iii媒介疾患の治療におけるその使用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ193935A (en) * 1979-06-18 1985-05-31 Richardson Merrell Inc 4-aroyl-imidazol-2-one derivatives;pharmaceutical compositions
ZA803332B (en) * 1979-06-18 1981-01-28 Richardson Merrell Inc Novel 4-aroylimidazol-2-ones

Also Published As

Publication number Publication date
GB2093031B (en) 1984-10-24
DK161250C (da) 1991-12-09
ES509636A0 (es) 1983-07-01
DE3274855D1 (de) 1987-02-05
JPH048421B2 (da) 1992-02-17
MY8600710A (en) 1986-12-31
ES8307002A1 (es) 1983-07-01
AU8048682A (en) 1982-08-26
EP0058435A3 (en) 1984-03-21
KR860001338B1 (ko) 1986-09-15
IE820333L (en) 1982-08-18
PH18106A (en) 1985-03-21
IL65010A0 (en) 1982-04-30
AU558789B2 (en) 1987-02-12
NZ199733A (en) 1985-05-31
HK61586A (en) 1986-08-29
EP0058435A2 (en) 1982-08-25
IE52422B1 (en) 1987-10-28
JPS57150668A (en) 1982-09-17
DK161250B (da) 1991-06-17
ZA82969B (en) 1983-09-28
CA1173047A (en) 1984-08-21
GR76025B (da) 1984-08-03
KR830009045A (ko) 1983-12-17
GB2093031A (en) 1982-08-25
ATE24496T1 (de) 1987-01-15
EP0058435B1 (en) 1986-12-30

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PUP Patent expired