MX9804482A - Quinolinas y quinazolinas utiles en terapias. - Google Patents

Quinolinas y quinazolinas utiles en terapias.

Info

Publication number
MX9804482A
MX9804482A MX9804482A MX9804482A MX9804482A MX 9804482 A MX9804482 A MX 9804482A MX 9804482 A MX9804482 A MX 9804482A MX 9804482 A MX9804482 A MX 9804482A MX 9804482 A MX9804482 A MX 9804482A
Authority
MX
Mexico
Prior art keywords
represent
alkyl
formula
alkoxy
optionally substituted
Prior art date
Application number
MX9804482A
Other languages
English (en)
Other versions
MXPA98004482A (es
Inventor
David Nathan Abraham Fox
Alan John Collis
Simon John Mantell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of MX9804482A publication Critical patent/MX9804482A/es
Publication of MXPA98004482A publication Critical patent/MXPA98004482A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Mushroom Cultivation (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Los compuestos de formula I (Ver Formula); en la que R1 representa alcoxi C1-4 opcionalmente sustituido con uno, o más átomos de fluor; R2 y R3 representan independientemente H, o alcoxi C1-6 (que se encuentra opcionalmente sustituido; R4 representa un anillo heterocíclico de 4, 5, 6 o 7 eslabones, estando el anillo opcionalmente condensado con un anillo de benceno o con un anillo heterocíclico de 5 o 6 eslabones, estando el sistema de anillos completo opcionalmente sustituido; X representa CH o N, y L está ausente, o representa un grupo cíclico de formula Ia (ver Formula); y las sales farmacéuticamente aceptables de los mismos, resultanutiles de terapias, en particular en el tratamiento de la hiperplasia prostática benigna.
MXPA/A/1998/004482A 1997-06-05 1998-06-04 Quinolinas y quinazolinas utiles en terapias MXPA98004482A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9711650.3A GB9711650D0 (en) 1997-06-05 1997-06-05 Compounds useful in therapy
GB9711650.3 1997-06-05

Publications (2)

Publication Number Publication Date
MX9804482A true MX9804482A (es) 1998-12-31
MXPA98004482A MXPA98004482A (es) 1999-02-01

Family

ID=

Also Published As

Publication number Publication date
DK0887344T3 (da) 2004-03-08
US6048864A (en) 2000-04-11
ATE255563T1 (de) 2003-12-15
CA2239603C (en) 2003-07-22
JP3163281B2 (ja) 2001-05-08
PT887344E (pt) 2004-02-27
US6417194B1 (en) 2002-07-09
DE69820159D1 (de) 2004-01-15
ES2210673T3 (es) 2004-07-01
EP0887344B1 (en) 2003-12-03
DE69820159T2 (de) 2004-05-27
GB9711650D0 (en) 1997-07-30
CA2239603A1 (en) 1998-12-05
EP0887344A1 (en) 1998-12-30
JPH1112274A (ja) 1999-01-19
BR9801778A (es) 2000-03-21

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Legal Events

Date Code Title Description
FG Grant or registration
MM Annulment or lapse due to non-payment of fees