JPS5642584A - Cell cultivation method - Google Patents

Cell cultivation method

Info

Publication number
JPS5642584A
JPS5642584A JP11883379A JP11883379A JPS5642584A JP S5642584 A JPS5642584 A JP S5642584A JP 11883379 A JP11883379 A JP 11883379A JP 11883379 A JP11883379 A JP 11883379A JP S5642584 A JPS5642584 A JP S5642584A
Authority
JP
Japan
Prior art keywords
cells
hollow
shells
hollow fibers
covered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11883379A
Other languages
English (en)
Japanese (ja)
Inventor
Koichi Yoshida
Fusakazu Hayano
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP11883379A priority Critical patent/JPS5642584A/ja
Priority to DE3035118A priority patent/DE3035118C2/de
Priority to FR8020019A priority patent/FR2476124A1/fr
Priority to US06/188,416 priority patent/US4391912A/en
Priority to GB8030253A priority patent/GB2062006B/en
Publication of JPS5642584A publication Critical patent/JPS5642584A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16—Hollow fibers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10—Hollow fibers or tubes

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP11883379A 1979-09-18 1979-09-18 Cell cultivation method Pending JPS5642584A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP11883379A JPS5642584A (en) 1979-09-18 1979-09-18 Cell cultivation method
DE3035118A DE3035118C2 (de) 1979-09-18 1980-09-17 Verfahren zur Kultivierung von schwimmenden Tierzellen und Vorrichtung zur Durchführung des Verfahrens
FR8020019A FR2476124A1 (fr) 1979-09-18 1980-09-17 Procede de culture de cellules, unite de culture de cellules animales flottantes, et dispositif pour culture de cellules
US06/188,416 US4391912A (en) 1979-09-18 1980-09-18 Cell cultivation method and floating animal cell culture unit for the same
GB8030253A GB2062006B (en) 1979-09-18 1980-09-18 Cultivating floating animal cells

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11883379A JPS5642584A (en) 1979-09-18 1979-09-18 Cell cultivation method

Publications (1)

Publication Number Publication Date
JPS5642584A true JPS5642584A (en) 1981-04-20

Family

ID=14746276

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11883379A Pending JPS5642584A (en) 1979-09-18 1979-09-18 Cell cultivation method

Country Status (5)

Country Link
US (1) US4391912A (cg-RX-API-DMAC10.html)
JP (1) JPS5642584A (cg-RX-API-DMAC10.html)
DE (1) DE3035118C2 (cg-RX-API-DMAC10.html)
FR (1) FR2476124A1 (cg-RX-API-DMAC10.html)
GB (1) GB2062006B (cg-RX-API-DMAC10.html)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156075A (ja) * 1984-08-28 1986-03-20 Teijin Ltd ヒト・ヒトハイブリド−マの培養方法
JPS61280270A (ja) * 1985-06-03 1986-12-10 Teijin Ltd 細胞培養装置
JPH01502315A (ja) * 1986-04-28 1989-08-17 エンドトロニックス　インコーポレーテッド 白血球を培養する方法
JPH02255079A (ja) * 1989-03-29 1990-10-15 Shimadzu Corp 細胞培養装置
US5376548A (en) * 1990-06-29 1994-12-27 Fuji Photo Film Co., Ltd. Bioreactor apparatus
JP2011103882A (ja) * 2009-11-16 2011-06-02 Shuhei Nakaji 細胞培養装置、細胞培養方法および細胞培養用プログラム

Families Citing this family (99)

* Cited by examiner, † Cited by third party
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DE2940446C2 (de) * 1979-10-05 1982-07-08 B. Braun Melsungen Ag, 3508 Melsungen Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen
US4442206A (en) * 1980-08-21 1984-04-10 Stanford University Method of using isotropic, porous-wall polymeric membrane, hollow-fibers for culture of microbes
US4440853A (en) * 1980-08-21 1984-04-03 Board Of Trustees Of The Leland Stanford Junior University Microbiological methods using hollow fiber membrane reactor
CH651587A5 (de) * 1980-11-18 1985-09-30 Chemap Ag Verfahren und vorrichtung zur submersen zuechtung von zellkulturen.
JPS5889179A (ja) * 1981-11-24 1983-05-27 Japan Synthetic Rubber Co Ltd 細胞培養床
EP0125303A4 (en) * 1982-11-16 1985-03-06 Univ California RAPID PRODUCTION OF BIOLOGICALS BY FERMENTATION IN A DENSE-LINED MICROBIAL MEMBRANE REACTOR.
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
US4937187A (en) * 1983-02-04 1990-06-26 Brown University Research Foundation Methods for separating malignant cells from clinical specimens
CA1221045A (en) * 1983-02-04 1987-04-28 Bjorn K. Lydersen Cell culture apparatus and process using an immobilized cell composite
US4734372A (en) * 1983-02-04 1988-03-29 Brown University Research Foundation Cell culturing methods and apparatus
DE3317550C2 (de) * 1983-05-13 1985-08-22 Stephan Priv.Doz.Dr.rer.nat.Dr.med.habil. 8000 München Nees Verfahren zum Züchten einer lückenlosen Zellschicht und Vorrichtung zur Durchführung dieses Verfahrens
US4804628A (en) * 1984-10-09 1989-02-14 Endotronics, Inc. Hollow fiber cell culture device and method of operation
CA1275273C (en) * 1984-10-09 1990-10-16 Micheal L. Gruenberg Hollow fiber cell culture device and method of operation
JPS62500356A (ja) * 1984-10-09 1987-02-19 エンドトロニツクス　インコ−ポレ−テツド 栄養素の潅流および生成物の濃度を改良した中空繊維培養装置および運転方法
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IL75554A (en) * 1985-06-18 1993-01-14 Yeda Res & Dev Matrix for cell cultivation in vitro
EP0220650A3 (en) * 1985-10-21 1988-08-24 Endotronics Inc. Method and device for culturing cells
US4720462A (en) * 1985-11-05 1988-01-19 Robert Rosenson Culture system for the culture of solid tissue masses and method of using the same
US5286646A (en) * 1985-11-25 1994-02-15 Boehringer Mannheim Gmbh Method for mammalian cell culture
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US4937194A (en) * 1986-05-12 1990-06-26 Baxter International Inc. Method for metering nutrient media to cell culture containers
IL82746A (en) * 1986-06-06 1994-10-07 Genentech Inc Process for producing biologically active tissue-type plasminogen activator
US4833083A (en) * 1987-05-26 1989-05-23 Sepragen Corporation Packed bed bioreactor
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US5081035A (en) * 1988-04-18 1992-01-14 The University Of Michigan Bioreactor system
US4973558A (en) * 1988-04-28 1990-11-27 Endotronics, Inc. Method of culturing cells using highly gas saturated media
DE3818776C2 (de) * 1988-06-02 1994-06-30 Maerkl Herbert Verfahren zur Kultivierung von Zellen in einem Fermenter und zur Durchführung des Verfahrens bestimmter Fermenter
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US5068195A (en) * 1988-11-02 1991-11-26 Du Pont Merck Pharmaceutical Company Dot matrix membrane cell expansion and maintenance vessel
FR2640638B1 (fr) * 1988-12-20 1991-02-15 Commissariat Energie Atomique Bioreacteur et dispositif pour la culture de cellules animales
US4937196A (en) * 1989-08-18 1990-06-26 Brunswick Corporation Membrane bioreactor system
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US5330908A (en) * 1992-12-23 1994-07-19 The United States Of America As Represented By The Administrator, National Aeronautics And Space Administration High density cell culture system
US5882918A (en) * 1995-08-08 1999-03-16 Genespan Corporation Cell culture incubator
US7101837B1 (en) * 1995-01-24 2006-09-05 Martinex R & D Inc. Recombinant human alpha-fetoprotein as a cell proliferative agent
US6660509B1 (en) 1995-03-28 2003-12-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US6133019A (en) * 1995-03-28 2000-10-17 Kinetic Biosystems, Inc. Centrifugal fermentation process
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US5622819A (en) * 1995-03-28 1997-04-22 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6214617B1 (en) 1995-03-28 2001-04-10 Kinetic Biosystems, Inc. Centrifugal fermentation process
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US5945338A (en) * 1995-06-26 1999-08-31 Vivorx Pharmaceuticals Method and apparatus for augmenting mass transfer in a rotating cell culture system
US5523228A (en) * 1995-07-07 1996-06-04 Hmri/Clmf Hydrodynamic cell culture environment for three dimensional tissue growth
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JP3673640B2 (ja) * 1997-05-15 2005-07-20 キヤノン株式会社 汚染媒体の浄化方法およびそれに用いる浄化装置
US6001643A (en) * 1997-08-04 1999-12-14 C-Med Inc. Controlled hydrodynamic cell culture environment for three dimensional tissue growth
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US6235196B1 (en) 1998-04-23 2001-05-22 Alliedsignal Inc. Biological wastewater treatment system
US20050158856A1 (en) * 1999-04-20 2005-07-21 Edelson Richard L. Methods for producing functional antigen presenting dendritic cells using biodegradable microparticles for delivery of antigenic materials
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US7270996B2 (en) * 2000-10-02 2007-09-18 Cannon Thomas F Automated bioculture and bioculture experiments system
US20020146817A1 (en) * 2000-10-02 2002-10-10 Cannon Thomas F. Automated bioculture and bioculture experiments system
FR2821947B1 (fr) * 2001-03-12 2003-05-16 Canon Kk Procede et dispositif de validation de parametres definissant une image
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US20030134415A1 (en) * 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
US20030134341A1 (en) * 2001-09-19 2003-07-17 Medcell Biologics, Llc. Th1 cell adoptive immunotherapy
US6667172B2 (en) 2001-09-19 2003-12-23 The Cleveland Clinic Foundation Cell and tissue culture modeling device and apparatus and method of using same
US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
US20040029266A1 (en) * 2002-08-09 2004-02-12 Emilio Barbera-Guillem Cell and tissue culture device
US6673598B1 (en) 2002-10-29 2004-01-06 Synthecon, Inc. Disposable culture bag
US7514256B2 (en) * 2005-02-11 2009-04-07 Emilio Barbera-Guillem Bioreactor for selectively controlling the molecular diffusion between fluids
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ZA200602094B (en) * 2006-01-16 2007-11-28 Reliance Life Sciences Pvt Ltd Device for culturing and transporting cells
DE102006031871B4 (de) * 2006-07-10 2008-10-23 Gerlach, Jörg, Dr.med. 3-D Petri-Schale zur Züchtung und Untersuchung von Zellen
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ES2665024T3 (es) * 2007-03-05 2018-04-24 Terumo Bct, Inc. Métodos para controlar el movimiento celular en biorreactores de fibra hueca
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EP2625264B1 (en) 2010-10-08 2022-12-07 Terumo BCT, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US9376655B2 (en) 2011-09-29 2016-06-28 Life Technologies Corporation Filter systems for separating microcarriers from cell culture solutions
CN104114266B (zh) 2011-09-30 2016-12-14 生命科技股份有限公司 具有膜喷洒器的容器
US9683207B2 (en) 2012-05-01 2017-06-20 FiberCell Production Solutions LLC Method for growing cells in hollow fibers
JP6466841B2 (ja) 2012-08-20 2019-02-06 テルモ ビーシーティー、インコーポレーテッド 細胞増殖システムのバイオリアクターにおける細胞の投入・分配方法
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4941579A (cg-RX-API-DMAC10.html) * 1972-05-18 1974-04-18
JPS5198382A (ja) * 1975-02-24 1976-08-30 Saibobaiyoki

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JPS4941579A (cg-RX-API-DMAC10.html) * 1972-05-18 1974-04-18
JPS5198382A (ja) * 1975-02-24 1976-08-30 Saibobaiyoki

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6156075A (ja) * 1984-08-28 1986-03-20 Teijin Ltd ヒト・ヒトハイブリド−マの培養方法
JPS61280270A (ja) * 1985-06-03 1986-12-10 Teijin Ltd 細胞培養装置
JPH01502315A (ja) * 1986-04-28 1989-08-17 エンドトロニックス　インコーポレーテッド 白血球を培養する方法
JPH02255079A (ja) * 1989-03-29 1990-10-15 Shimadzu Corp 細胞培養装置
US5376548A (en) * 1990-06-29 1994-12-27 Fuji Photo Film Co., Ltd. Bioreactor apparatus
JP2011103882A (ja) * 2009-11-16 2011-06-02 Shuhei Nakaji 細胞培養装置、細胞培養方法および細胞培養用プログラム

Also Published As

Publication number Publication date
GB2062006A (en) 1981-05-20
FR2476124A1 (fr) 1981-08-21
DE3035118C2 (de) 1982-09-23
DE3035118A1 (de) 1981-03-19
GB2062006B (en) 1983-08-24
US4391912A (en) 1983-07-05
FR2476124B1 (cg-RX-API-DMAC10.html) 1983-05-27

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