ES2091819T3 - Unidad de cultivo celular con aparato de oxigenacion de medio de cultivo. - Google Patents

Unidad de cultivo celular con aparato de oxigenacion de medio de cultivo.

Info

Publication number
ES2091819T3
ES2091819T3 ES90903997T ES90903997T ES2091819T3 ES 2091819 T3 ES2091819 T3 ES 2091819T3 ES 90903997 T ES90903997 T ES 90903997T ES 90903997 T ES90903997 T ES 90903997T ES 2091819 T3 ES2091819 T3 ES 2091819T3
Authority
ES
Spain
Prior art keywords
tubes
oxygen
cell culture
culture unit
oxygenation device
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90903997T
Other languages
English (en)
Inventor
Robert V Oakley
Van Taiariol
Rudolf F Bliem
James F Long
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Baxter International Inc
Original Assignee
Baxter International Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter International Inc filed Critical Baxter International Inc
Application granted granted Critical
Publication of ES2091819T3 publication Critical patent/ES2091819T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16Hollow fibers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/24Gas permeable parts

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Clinical Laboratory Science (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

UN OXIGENADOR (20), PARTICULARMENTE PARA PROVEER OXIGENO Y/O DIOXIDO DE CARBONO, U OTROS GASES, PARA MEDIO DE CULTIVO USADO EN EL CULTIVO "IN VITRO" DE CELULAS ANIMALES, COMPRENDE UNA COLECCION DE TUBOS (22) ALARGADOS, PERMEABLES AL GAS E IMPERMEABLES AL LIQUIDO, A TRAVES DE LOS CUALES EL GAS QUE CONTIENE OXIGENO FLUYE Y PENETRA A TRAVES DE LAS PAREDES DE LOS TUBOS PARA PROVEER OXIGENO GASEOSO SIN BURBUJAS NI ESPUMA A UN MEDIO EN CONTACTO CON, O EN LA PROXIMIDAD, DE LOS TUBOS, TENIENDO LOS TUBOS INDIVIDUALES UN DIAMETRO DE SALIDA DE MENOS DE ALREDEDOR DE 1 MM Y UN ESPESOR DE PARED DE DESDE ALREDEDOR DE 0,1 MM A ALREDEDOR DE 0,25; EXTENDIENDOSE, PREFERIBLEMENTE, SEPARADOS RADIALMENTE EL CONJUNTO DE TUBOS EN AL MENOS UN PUNTO (50) A LO LARGO DE SU LONGITUD.
ES90903997T 1989-03-27 1989-11-17 Unidad de cultivo celular con aparato de oxigenacion de medio de cultivo. Expired - Lifetime ES2091819T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/329,013 US4897359A (en) 1989-03-27 1989-03-27 Apparatus for oxygenating culture medium

Publications (1)

Publication Number Publication Date
ES2091819T3 true ES2091819T3 (es) 1996-11-16

Family

ID=23283474

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90903997T Expired - Lifetime ES2091819T3 (es) 1989-03-27 1989-11-17 Unidad de cultivo celular con aparato de oxigenacion de medio de cultivo.

Country Status (8)

Country Link
US (1) US4897359A (es)
EP (1) EP0416061B1 (es)
JP (1) JP2935065B2 (es)
AT (1) ATE140478T1 (es)
CA (1) CA2008585C (es)
DE (1) DE68926858T2 (es)
ES (1) ES2091819T3 (es)
WO (1) WO1990011346A1 (es)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
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DE9413575U1 (de) * 1994-08-24 1994-11-03 Forschungszentrum Jülich GmbH, 52428 Jülich Reaktor für die Zellkulturtechnik mit blasenfreier Begasung
JP3130751B2 (ja) * 1995-01-30 2001-01-31 株式会社荏原製作所 オゾン水製造方法及び装置
US6133019A (en) * 1995-03-28 2000-10-17 Kinetic Biosystems, Inc. Centrifugal fermentation process
US6214617B1 (en) 1995-03-28 2001-04-10 Kinetic Biosystems, Inc. Centrifugal fermentation process
US5622819A (en) * 1995-03-28 1997-04-22 Kinetic Biosystems, Inc. Centrifugal fermentation process
US20050266548A1 (en) * 1995-03-28 2005-12-01 Kbi Biopharma, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation with improved rotor
US6916652B2 (en) * 1995-03-28 2005-07-12 Kinetic Biosystems, Inc. Biocatalyst chamber encapsulation system for bioremediation and fermentation
US6660509B1 (en) 1995-03-28 2003-12-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US6209855B1 (en) * 1999-05-10 2001-04-03 Canzone Limited Gas/liquid mixing apparatus and method
US6703217B2 (en) 2000-01-31 2004-03-09 Kinetic Biosystems, Inc. Methods and devices for remediation and fermentation
US6332980B1 (en) * 2000-03-13 2001-12-25 Jack Moorehead System for separating algae and other contaminants from a water stream
NO20025537D0 (no) * 2002-11-18 2002-11-18 Norsk Hydro As Et fleksibelt rörsystem, samt metode for fremstilling og bruk av slikt system
DE102005021305A1 (de) * 2005-05-09 2006-11-16 Fresenius Medical Care Deutschland Gmbh Reaktoreinheit und Reaktor mit einer derartigen Reaktoreinheit
US7745209B2 (en) 2005-07-26 2010-06-29 Corning Incorporated Multilayered cell culture apparatus
EP2092052B1 (en) 2006-12-07 2020-09-23 Wilson Wolf Manufacturing Corporation Highly efficient gas permeable devices for culturing cells
US8236081B2 (en) * 2007-07-17 2012-08-07 Teleflex Medical Incorporated Permeable membrane water dissipation device
US20090032446A1 (en) * 2007-08-01 2009-02-05 Triwatech, L.L.C. Mobile station and methods for diagnosing and modeling site specific effluent treatment facility requirements
US8778669B2 (en) * 2009-07-22 2014-07-15 Corning Incorporated Multilayer tissue culture vessel
US11193142B2 (en) * 2011-10-24 2021-12-07 AgorFora ApS Methods and apparatus for hydrogen based biogas upgrading
US9005550B2 (en) 2012-10-29 2015-04-14 Corning Incorporated Multi-layered cell culture vessel with manifold grips
KR20150104465A (ko) * 2014-03-05 2015-09-15 두산중공업 주식회사 포화장치 및 이를 구비한 수처리장치
US11471636B2 (en) 2015-04-15 2022-10-18 Medline Industries, Lp Moisture removal and condensation and humidity management apparatus for a breathing circuit
US10477883B2 (en) 2015-08-25 2019-11-19 Cornelius, Inc. Gas injection assemblies for batch beverages having spargers
US10785996B2 (en) 2015-08-25 2020-09-29 Cornelius, Inc. Apparatuses, systems, and methods for inline injection of gases into liquids
WO2018075638A1 (en) 2016-10-19 2018-04-26 Teleflex Medical Incorporated Moisture removal and condensation and humidity management apparatus for a breathing circuit
US10960165B2 (en) 2017-07-10 2021-03-30 Teleflex Medical Incorporated Moisture removal and condensation and humidity management apparatus for a breathing circuit
US11028727B2 (en) * 2017-10-06 2021-06-08 General Electric Company Foaming nozzle of a cleaning system for turbine engines
CN108300661A (zh) * 2018-02-13 2018-07-20 京东方科技集团股份有限公司 培养装置和培养设备
WO2020076776A1 (en) * 2018-10-10 2020-04-16 Boehringer Ingelheim International Gmbh Method for membrane gas transfer in high density bioreactor culture
US11040314B2 (en) 2019-01-08 2021-06-22 Marmon Foodservice Technologies, Inc. Apparatuses, systems, and methods for injecting gasses into beverages
KR20220014890A (ko) * 2019-06-04 2022-02-07 벌티모어 에어코일 컴파니 인코포레이티드 튜브형 멤브레인 열교환기
WO2024118424A1 (en) * 2022-11-30 2024-06-06 Corning Incorporated Systems and methods for oxygenating culture media in perfusion bioreactors

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3821087A (en) * 1972-05-18 1974-06-28 Dedrick R Cell culture on semi-permeable tubular membranes
CH593339A5 (es) * 1973-07-02 1977-11-30 Monsanto Co
US4144136A (en) * 1977-06-06 1979-03-13 Institut Armand-Frappier Apparatus for cellular culture
DE2940446C2 (de) * 1979-10-05 1982-07-08 B. Braun Melsungen Ag, 3508 Melsungen Züchtung von tierischen Zellen in Suspensions- und Monolayerkulturen in Fermentationsgefäßen
JPS59218161A (ja) * 1983-05-27 1984-12-08 テルモ株式会社 中空繊維型人工肺およびその製造方法
US4583969A (en) * 1984-06-26 1986-04-22 Mortensen J D Apparatus and method for in vivo extrapulmonary blood gas exchange
US4720462A (en) * 1985-11-05 1988-01-19 Robert Rosenson Culture system for the culture of solid tissue masses and method of using the same
JPS63230079A (ja) * 1987-03-18 1988-09-26 Toyobo Co Ltd 動物細胞大量培養用通気装置
JPH01225475A (ja) * 1988-03-07 1989-09-08 Japan Gore Tex Inc 培養装置

Also Published As

Publication number Publication date
CA2008585A1 (en) 1990-09-27
EP0416061A4 (en) 1991-12-18
EP0416061A1 (en) 1991-03-13
JP2935065B2 (ja) 1999-08-16
CA2008585C (en) 1999-03-23
DE68926858D1 (de) 1996-08-22
JPH03504925A (ja) 1991-10-31
WO1990011346A1 (en) 1990-10-04
EP0416061B1 (en) 1996-07-17
ATE140478T1 (de) 1996-08-15
US4897359A (en) 1990-01-30
DE68926858T2 (de) 1997-01-16

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