JPS563000A - Water-soluble cholesterol derivative - Google Patents
Water-soluble cholesterol derivativeInfo
- Publication number
- JPS563000A JPS563000A JP7676779A JP7676779A JPS563000A JP S563000 A JPS563000 A JP S563000A JP 7676779 A JP7676779 A JP 7676779A JP 7676779 A JP7676779 A JP 7676779A JP S563000 A JPS563000 A JP S563000A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- dibasic acid
- organic dibasic
- half ester
- acid half
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7676779A JPS563000A (en) | 1979-06-20 | 1979-06-20 | Water-soluble cholesterol derivative |
CA000352892A CA1154755A (en) | 1979-06-20 | 1980-05-28 | Cholesterol derivatives |
SE8004125A SE445833B (sv) | 1979-06-20 | 1980-06-03 | Halvester av organisk tvabasisk syra och 7-ketokolesterol eller 7-hydroxikolesterol |
US06/156,091 US4304726A (en) | 1979-06-20 | 1980-06-03 | Process for the preparation of cholesterol derivatives |
GB8018483A GB2053924B (en) | 1979-06-20 | 1980-06-05 | Immunosuppressive 3-hemiesters of7-oxygenated cholesterol |
DE3022788A DE3022788C2 (de) | 1979-06-20 | 1980-06-18 | 7-Ketocholesterin- und 7-Hydroxycholesterin-berstein- bzw. -phthal-säure-halbester und ihre Salze und ihre Verwendung als Immunsuppressiva und Antiphlogistika |
FR8013618A FR2459248A1 (fr) | 1979-06-20 | 1980-06-19 | Hemi-esters du cholesterol utilisables en medecine et leur procede de fabrication |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7676779A JPS563000A (en) | 1979-06-20 | 1979-06-20 | Water-soluble cholesterol derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS563000A true JPS563000A (en) | 1981-01-13 |
Family
ID=13614739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP7676779A Pending JPS563000A (en) | 1979-06-20 | 1979-06-20 | Water-soluble cholesterol derivative |
Country Status (7)
Country | Link |
---|---|
US (1) | US4304726A (ja) |
JP (1) | JPS563000A (ja) |
CA (1) | CA1154755A (ja) |
DE (1) | DE3022788C2 (ja) |
FR (1) | FR2459248A1 (ja) |
GB (1) | GB2053924B (ja) |
SE (1) | SE445833B (ja) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60258198A (ja) * | 1984-06-04 | 1985-12-20 | Amano Pharmaceut Co Ltd | トリテルペンアルコ−ル有機酸エステル及びその製造法 |
JPWO2003022866A1 (ja) * | 2001-09-07 | 2004-12-24 | 栄次 松浦 | β2−グリコプロテインIに対するリガンド及びその用途 |
JP2012516900A (ja) * | 2009-02-05 | 2012-07-26 | トーカイ ファーマシューティカルズ,インク. | ステロイド性cyp17阻害剤/抗アンドロゲン剤の新しいプロドラッグ |
US9808472B2 (en) | 2013-08-12 | 2017-11-07 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
US9884067B2 (en) | 2013-03-14 | 2018-02-06 | University Of Maryland, Baltimore | Androgen receptor down-regulating agents and uses thereof |
US10098896B2 (en) | 2005-03-02 | 2018-10-16 | University Of Maryland Baltimore | C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens, in vitro biological activities, pharmacokinetics and antitumor activity |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4442037A (en) * | 1981-03-13 | 1984-04-10 | Yoshio Arakawa | Water-soluble cholesterol derivative |
DE3803757A1 (de) * | 1988-02-08 | 1989-08-17 | Boehringer Mannheim Gmbh | Cholesterin-esterase-farbsubstrat |
US5496806A (en) * | 1990-01-23 | 1996-03-05 | R. Erich Klemke | Glycoside compounds and production and use thereof |
FI974648A (fi) | 1997-09-09 | 1999-05-06 | Raisio Benecol Oy | Hydroksihappo-, maitohappo- ja hydroksialkanoaattiesterit ja niiden käyttö |
IL146223A0 (en) | 1999-04-30 | 2002-07-25 | Arch Dev Corp | Steroid derivatives |
EP1385868A4 (en) * | 2001-02-08 | 2004-12-08 | Univ Chicago | STEROID DERIVATIVES |
US7078396B2 (en) * | 2001-05-03 | 2006-07-18 | Arch Development Corporation | Method of treating disorder related to high cholesterol concentration |
US20070197484A1 (en) * | 2001-05-03 | 2007-08-23 | Ching Song | Method of treating disorder related to high cholesterol concentration |
DK1392713T3 (da) * | 2001-05-03 | 2008-02-18 | Univ Chicago | Lever-X-receptoragonister |
CA2482195A1 (en) * | 2002-04-12 | 2003-10-23 | The University Of Chicago | Farnesoid x-activated receptor agonists |
US20070032464A1 (en) * | 2004-10-08 | 2007-02-08 | Shutsung Liao | Methods of treating cancers |
US8829213B2 (en) * | 2009-07-29 | 2014-09-09 | The University Of Chicago | Liver X receptor agonists |
EP2522350B1 (de) * | 2011-05-12 | 2013-07-31 | Immunopharm AG | Verwendung der Wirkstoffkombination aus einem 1-Diethylaminoethyl-3-Chinoxalin-2-on Derivat und einem Oxysterol zur Durchbrechung von Resistenzen bei der Behandlung von Krebs und zur Erhöhung der Immunleistungsfähigkeit bei Krebs, bakteriellen und viralen Erkrankungen, Autoimmunerkrankungen, erhöhter Stress- und Umweltbelastung |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1224738B (de) * | 1960-12-29 | 1966-09-15 | Takeda Chemical Industries Ltd | Verfahren zur Herstellung von Cholestan-3, 5, 6-triol-3-estern oder -3, 6-diestern soowie von deren Salzen |
GB1553540A (en) * | 1977-02-23 | 1979-09-26 | Green Cross Corp | Medicaments containing cholesterol derivatives |
US4202891A (en) * | 1977-05-16 | 1980-05-13 | Kandutsch Andrew A | 15-Oxygenated sterol compounds and the use of such compounds to inhibit the biosynthesis of sterols |
US4189400A (en) * | 1977-08-17 | 1980-02-19 | Bonderman Dean P | Compound useful in cholesterol assay procedures |
US4225525A (en) * | 1979-02-08 | 1980-09-30 | Hoffmann-La Roche Inc. | Vitamin D3 metabolite derivatives |
-
1979
- 1979-06-20 JP JP7676779A patent/JPS563000A/ja active Pending
-
1980
- 1980-05-28 CA CA000352892A patent/CA1154755A/en not_active Expired
- 1980-06-03 SE SE8004125A patent/SE445833B/sv not_active IP Right Cessation
- 1980-06-03 US US06/156,091 patent/US4304726A/en not_active Expired - Lifetime
- 1980-06-05 GB GB8018483A patent/GB2053924B/en not_active Expired
- 1980-06-18 DE DE3022788A patent/DE3022788C2/de not_active Expired
- 1980-06-19 FR FR8013618A patent/FR2459248A1/fr active Granted
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60258198A (ja) * | 1984-06-04 | 1985-12-20 | Amano Pharmaceut Co Ltd | トリテルペンアルコ−ル有機酸エステル及びその製造法 |
JPH0140040B2 (ja) * | 1984-06-04 | 1989-08-24 | Amano Pharma Co Ltd | |
JPWO2003022866A1 (ja) * | 2001-09-07 | 2004-12-24 | 栄次 松浦 | β2−グリコプロテインIに対するリガンド及びその用途 |
US10098896B2 (en) | 2005-03-02 | 2018-10-16 | University Of Maryland Baltimore | C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens, in vitro biological activities, pharmacokinetics and antitumor activity |
JP2012516900A (ja) * | 2009-02-05 | 2012-07-26 | トーカイ ファーマシューティカルズ,インク. | ステロイド性cyp17阻害剤/抗アンドロゲン剤の新しいプロドラッグ |
US9884067B2 (en) | 2013-03-14 | 2018-02-06 | University Of Maryland, Baltimore | Androgen receptor down-regulating agents and uses thereof |
US9808472B2 (en) | 2013-08-12 | 2017-11-07 | Tokai Pharmaceuticals, Inc. | Biomarkers for treatment of neoplastic disorders using androgen-targeted therapies |
Also Published As
Publication number | Publication date |
---|---|
US4304726A (en) | 1981-12-08 |
GB2053924A (en) | 1981-02-11 |
SE445833B (sv) | 1986-07-21 |
DE3022788A1 (de) | 1981-01-08 |
GB2053924B (en) | 1983-04-27 |
FR2459248B1 (ja) | 1983-10-28 |
CA1154755A (en) | 1983-10-04 |
DE3022788C2 (de) | 1982-08-12 |
SE8004125L (sv) | 1980-12-21 |
FR2459248A1 (fr) | 1981-01-09 |
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