JPS5535017A - Beta-nitrostyrene derivative - Google Patents

Beta-nitrostyrene derivative

Info

Publication number
JPS5535017A
JPS5535017A JP10786778A JP10786778A JPS5535017A JP S5535017 A JPS5535017 A JP S5535017A JP 10786778 A JP10786778 A JP 10786778A JP 10786778 A JP10786778 A JP 10786778A JP S5535017 A JPS5535017 A JP S5535017A
Authority
JP
Japan
Prior art keywords
compound
reacted
give
nitrostyrene
solvent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10786778A
Other languages
Japanese (ja)
Other versions
JPS585902B2 (en
Inventor
Tadahiro Doi
Shizuo Nakamura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to JP10786778A priority Critical patent/JPS585902B2/en
Publication of JPS5535017A publication Critical patent/JPS5535017A/en
Publication of JPS585902B2 publication Critical patent/JPS585902B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:A β-nitrostyrene derivative and its acid-addition salt, I (R1 is H or lower alkyl; X is halogen).
EXAMPLE: 4-Amino-3, 5-dichloro-β-nitrostyrene.
USE: Anti-fungal agents. Preventives for thrombosis. It has excellent antifungal action and blood platelet-coagulation suppressing activity.
PROCESS: For example, a cpmpound II is reacted with a halogenating agent in a slovent to give a compound III. The compound III is reacted with a reducing agent in a solvent to give a compound IV. The compound IV is reacted with an oxidizing agent in an solvent to give a compound V. The compound V is reacted with a compound VI to give the desired compound I.
COPYRIGHT: (C)1980,JPO&Japio
JP10786778A 1978-09-01 1978-09-01 β↓-nitrostyrene derivative Expired JPS585902B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10786778A JPS585902B2 (en) 1978-09-01 1978-09-01 β↓-nitrostyrene derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10786778A JPS585902B2 (en) 1978-09-01 1978-09-01 β↓-nitrostyrene derivative

Publications (2)

Publication Number Publication Date
JPS5535017A true JPS5535017A (en) 1980-03-11
JPS585902B2 JPS585902B2 (en) 1983-02-02

Family

ID=14470080

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10786778A Expired JPS585902B2 (en) 1978-09-01 1978-09-01 β↓-nitrostyrene derivative

Country Status (1)

Country Link
JP (1) JPS585902B2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145958A (en) * 1989-10-04 1992-09-08 Bayer Aktiengesellschaft Process for the preparation of 2,4- or 2,6-dihalogeno-aniline
JP2015518007A (en) * 2012-05-30 2015-06-25 バイオディエム、リミテッドＢｉｏｄｉｅｍ Ｌｉｍｉｔｅｄ Method for treating skedosporia infection

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62115311U (en) * 1986-01-13 1987-07-22

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145958A (en) * 1989-10-04 1992-09-08 Bayer Aktiengesellschaft Process for the preparation of 2,4- or 2,6-dihalogeno-aniline
JP2015518007A (en) * 2012-05-30 2015-06-25 バイオディエム、リミテッドＢｉｏｄｉｅｍ Ｌｉｍｉｔｅｄ Method for treating skedosporia infection

Also Published As

Publication number Publication date
JPS585902B2 (en) 1983-02-02

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