JPS57131738A - Novel cyclohexanecarboxylic acid derivative - Google Patents
Novel cyclohexanecarboxylic acid derivativeInfo
- Publication number
- JPS57131738A JPS57131738A JP1862181A JP1862181A JPS57131738A JP S57131738 A JPS57131738 A JP S57131738A JP 1862181 A JP1862181 A JP 1862181A JP 1862181 A JP1862181 A JP 1862181A JP S57131738 A JPS57131738 A JP S57131738A
- Authority
- JP
- Japan
- Prior art keywords
- action
- cyclohexanecarboxylic acid
- acid derivative
- methyl
- formulai
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
NEW MATERIAL:A cyclohexanecarboxylic acid derivative shown by the formulaI(R1 is H or methyl; R2 is H or lower alkyl; R3 is H or hydroxyl group; R4 is 4-methylpentyl, 4-methyl-3-pentenyl).
EXAMPLE: t-3-Hydroxyl-c-4-( 4-methylpentyl )-r-1-cyclohexanecarboxylic acid methyl ester.
USE: Having pharmaceutical actions such as antitumor action, antiallergic action, liver function improving action, antihyperlipemia action, antirheumatic action, etc., useful as a drug. Having low side effects.
PROCESS: For example, a compound shown by the formula II is reacted with an organic boron compound such as diborane in an inert solvent such as tetrahydrofuran, etc. at 0W30°C, and oxidized with alkaline hydrogen peroxide, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1862181A JPS57131738A (en) | 1981-02-09 | 1981-02-09 | Novel cyclohexanecarboxylic acid derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1862181A JPS57131738A (en) | 1981-02-09 | 1981-02-09 | Novel cyclohexanecarboxylic acid derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS57131738A true JPS57131738A (en) | 1982-08-14 |
Family
ID=11976690
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1862181A Pending JPS57131738A (en) | 1981-02-09 | 1981-02-09 | Novel cyclohexanecarboxylic acid derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS57131738A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5068414A (en) * | 1990-01-26 | 1991-11-26 | Celgene Corporation | Hydroxyterephthalic acid |
JP2013506658A (en) * | 2009-09-30 | 2013-02-28 | ウィズケム カンパニー・リミテッド | Process for producing 1,4-disubstituted cyclohexane derivatives |
-
1981
- 1981-02-09 JP JP1862181A patent/JPS57131738A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5068414A (en) * | 1990-01-26 | 1991-11-26 | Celgene Corporation | Hydroxyterephthalic acid |
JP2013506658A (en) * | 2009-09-30 | 2013-02-28 | ウィズケム カンパニー・リミテッド | Process for producing 1,4-disubstituted cyclohexane derivatives |
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