JPS57131738A - Novel cyclohexanecarboxylic acid derivative - Google Patents

Novel cyclohexanecarboxylic acid derivative

Info

Publication number
JPS57131738A
JPS57131738A JP1862181A JP1862181A JPS57131738A JP S57131738 A JPS57131738 A JP S57131738A JP 1862181 A JP1862181 A JP 1862181A JP 1862181 A JP1862181 A JP 1862181A JP S57131738 A JPS57131738 A JP S57131738A
Authority
JP
Japan
Prior art keywords
action
cyclohexanecarboxylic acid
acid derivative
methyl
formulai
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP1862181A
Other languages
Japanese (ja)
Inventor
Kanji Noda
Akira Nakagawa
Kenji Yamagata
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP1862181A priority Critical patent/JPS57131738A/en
Publication of JPS57131738A publication Critical patent/JPS57131738A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:A cyclohexanecarboxylic acid derivative shown by the formulaI(R1 is H or methyl; R2 is H or lower alkyl; R3 is H or hydroxyl group; R4 is 4-methylpentyl, 4-methyl-3-pentenyl).
EXAMPLE: t-3-Hydroxyl-c-4-( 4-methylpentyl )-r-1-cyclohexanecarboxylic acid methyl ester.
USE: Having pharmaceutical actions such as antitumor action, antiallergic action, liver function improving action, antihyperlipemia action, antirheumatic action, etc., useful as a drug. Having low side effects.
PROCESS: For example, a compound shown by the formula II is reacted with an organic boron compound such as diborane in an inert solvent such as tetrahydrofuran, etc. at 0W30°C, and oxidized with alkaline hydrogen peroxide, to give a compound shown by the formulaI.
COPYRIGHT: (C)1982,JPO&Japio
JP1862181A 1981-02-09 1981-02-09 Novel cyclohexanecarboxylic acid derivative Pending JPS57131738A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP1862181A JPS57131738A (en) 1981-02-09 1981-02-09 Novel cyclohexanecarboxylic acid derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP1862181A JPS57131738A (en) 1981-02-09 1981-02-09 Novel cyclohexanecarboxylic acid derivative

Publications (1)

Publication Number Publication Date
JPS57131738A true JPS57131738A (en) 1982-08-14

Family

ID=11976690

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1862181A Pending JPS57131738A (en) 1981-02-09 1981-02-09 Novel cyclohexanecarboxylic acid derivative

Country Status (1)

Country Link
JP (1) JPS57131738A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068414A (en) * 1990-01-26 1991-11-26 Celgene Corporation Hydroxyterephthalic acid
JP2013506658A (en) * 2009-09-30 2013-02-28 ウィズケム カンパニー・リミテッド Process for producing 1,4-disubstituted cyclohexane derivatives

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5068414A (en) * 1990-01-26 1991-11-26 Celgene Corporation Hydroxyterephthalic acid
JP2013506658A (en) * 2009-09-30 2013-02-28 ウィズケム カンパニー・リミテッド Process for producing 1,4-disubstituted cyclohexane derivatives

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