JPS56138140A - Preparation of 2- p-halomethylphenyl propionic acid or its ester - Google Patents
Preparation of 2- p-halomethylphenyl propionic acid or its esterInfo
- Publication number
- JPS56138140A JPS56138140A JP4129180A JP4129180A JPS56138140A JP S56138140 A JPS56138140 A JP S56138140A JP 4129180 A JP4129180 A JP 4129180A JP 4129180 A JP4129180 A JP 4129180A JP S56138140 A JPS56138140 A JP S56138140A
- Authority
- JP
- Japan
- Prior art keywords
- condensing agent
- ester
- readily
- propionic acid
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 title abstract 4
- 150000002148 esters Chemical class 0.000 title abstract 2
- 235000019260 propionic acid Nutrition 0.000 title abstract 2
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003795 chemical substances by application Substances 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- 229910052736 halogen Inorganic materials 0.000 abstract 2
- 150000002367 halogens Chemical class 0.000 abstract 2
- 206010007269 Carcinogenicity Diseases 0.000 abstract 1
- 238000005727 Friedel-Crafts reaction Methods 0.000 abstract 1
- 239000002841 Lewis acid Substances 0.000 abstract 1
- 229910021627 Tin(IV) chloride Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 230000007670 carcinogenicity Effects 0.000 abstract 1
- 231100000260 carcinogenicity Toxicity 0.000 abstract 1
- 239000003054 catalyst Substances 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- YPGCWEMNNLXISK-UHFFFAOYSA-N hydratropic acid Chemical compound OC(=O)C(C)C1=CC=CC=C1 YPGCWEMNNLXISK-UHFFFAOYSA-N 0.000 abstract 1
- 150000007517 lewis acids Chemical class 0.000 abstract 1
- -1 propionic acid compound Chemical class 0.000 abstract 1
- 239000002994 raw material Substances 0.000 abstract 1
- PUGUQINMNYINPK-UHFFFAOYSA-N tert-butyl 4-(2-chloroacetyl)piperazine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1 PUGUQINMNYINPK-UHFFFAOYSA-N 0.000 abstract 1
- HPGGPRDJHPYFRM-UHFFFAOYSA-J tin(iv) chloride Chemical compound Cl[Sn](Cl)(Cl)Cl HPGGPRDJHPYFRM-UHFFFAOYSA-J 0.000 abstract 1
Landscapes
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4129180A JPS56138140A (en) | 1980-03-31 | 1980-03-31 | Preparation of 2- p-halomethylphenyl propionic acid or its ester |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP4129180A JPS56138140A (en) | 1980-03-31 | 1980-03-31 | Preparation of 2- p-halomethylphenyl propionic acid or its ester |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS56138140A true JPS56138140A (en) | 1981-10-28 |
| JPS6334856B2 JPS6334856B2 (en, 2012) | 1988-07-12 |
Family
ID=12604337
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP4129180A Granted JPS56138140A (en) | 1980-03-31 | 1980-03-31 | Preparation of 2- p-halomethylphenyl propionic acid or its ester |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS56138140A (en, 2012) |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567293A (en) * | 1981-10-14 | 1986-01-28 | Kureha Kagaku Kogyo Kabushiki Kaisha | 2-[Para-(2-substituted or unsubstituted-3,3,3-tri-fluoropropyl)phenyl]propionic acid or a salt thereof |
| EP0889020A1 (en) * | 1997-07-04 | 1999-01-07 | Kolon Industries, Inc. | A process for the production of benzene derivatives |
| KR19990015050A (ko) * | 1997-08-01 | 1999-03-05 | 구광시 | 페닐프로피온산 유도체의 제조방법 |
| KR100448642B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 페닐프로피온산 유도체의 제조방법 |
| KR100448640B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 페닐프로피온산 유도체의 제조방법 |
| KR100448641B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 2-(4-할로메틸페닐)프로피온산의 제조 방법 |
| CN106349051A (zh) * | 2016-08-25 | 2017-01-25 | 宁波博撷化学科技有限公司 | 一种2‑(4‑氯甲基苯基)丙酸甲酯的制备方法 |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63167550U (en, 2012) * | 1987-04-22 | 1988-11-01 |
-
1980
- 1980-03-31 JP JP4129180A patent/JPS56138140A/ja active Granted
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4567293A (en) * | 1981-10-14 | 1986-01-28 | Kureha Kagaku Kogyo Kabushiki Kaisha | 2-[Para-(2-substituted or unsubstituted-3,3,3-tri-fluoropropyl)phenyl]propionic acid or a salt thereof |
| EP0889020A1 (en) * | 1997-07-04 | 1999-01-07 | Kolon Industries, Inc. | A process for the production of benzene derivatives |
| KR19990015050A (ko) * | 1997-08-01 | 1999-03-05 | 구광시 | 페닐프로피온산 유도체의 제조방법 |
| KR100448642B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 페닐프로피온산 유도체의 제조방법 |
| KR100448640B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 페닐프로피온산 유도체의 제조방법 |
| KR100448641B1 (ko) * | 1997-08-01 | 2004-11-16 | 주식회사 코오롱 | 2-(4-할로메틸페닐)프로피온산의 제조 방법 |
| CN106349051A (zh) * | 2016-08-25 | 2017-01-25 | 宁波博撷化学科技有限公司 | 一种2‑(4‑氯甲基苯基)丙酸甲酯的制备方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6334856B2 (en, 2012) | 1988-07-12 |
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