JPS56108767A - Bismoranoline derivative - Google Patents
Bismoranoline derivativeInfo
- Publication number
- JPS56108767A JPS56108767A JP917380A JP917380A JPS56108767A JP S56108767 A JPS56108767 A JP S56108767A JP 917380 A JP917380 A JP 917380A JP 917380 A JP917380 A JP 917380A JP S56108767 A JPS56108767 A JP S56108767A
- Authority
- JP
- Japan
- Prior art keywords
- derivative
- hyperglycoplasmia
- formula
- bismoranoline
- naphthalene
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 abstract 3
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- LXBIFEVIBLOUGU-UHFFFAOYSA-N Deoxymannojirimycin Natural products OCC1NCC(O)C(O)C1O LXBIFEVIBLOUGU-UHFFFAOYSA-N 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000007107 Stomach Ulcer Diseases 0.000 abstract 1
- -1 alcohol compound Chemical class 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 208000000718 duodenal ulcer Diseases 0.000 abstract 1
- LXBIFEVIBLOUGU-JGWLITMVSA-N duvoglustat Chemical compound OC[C@H]1NC[C@H](O)[C@@H](O)[C@@H]1O LXBIFEVIBLOUGU-JGWLITMVSA-N 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N ether Substances CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- 201000005917 gastric ulcer Diseases 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 125000001624 naphthyl group Chemical group 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000003449 preventive effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Diabetes (AREA)
- General Chemical & Material Sciences (AREA)
- Emergency Medicine (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Endocrinology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP917380A JPS56108767A (en) | 1980-01-28 | 1980-01-28 | Bismoranoline derivative |
GB8100185A GB2067989B (en) | 1980-01-28 | 1981-01-06 | Bis-moranoline derivatives |
IT47608/81A IT1170641B (it) | 1980-01-28 | 1981-01-21 | Derivati della bis-moranolina |
FR8101520A FR2474498B1 (fr) | 1980-01-28 | 1981-01-27 | Derives de bis-moranoline et leur utilisation pour inhiber l'augmentation de sucre dans le sang |
CH51481A CH643830A5 (de) | 1980-01-28 | 1981-01-27 | Bis-moranolin-derivate. |
DE19813102769 DE3102769A1 (de) | 1980-01-28 | 1981-01-28 | "bis-moranolinderivate" |
US06/247,885 US4336373A (en) | 1980-01-28 | 1981-03-26 | Bis-piperidine compounds |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP917380A JPS56108767A (en) | 1980-01-28 | 1980-01-28 | Bismoranoline derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS56108767A true JPS56108767A (en) | 1981-08-28 |
JPS6312063B2 JPS6312063B2 (en, 2012) | 1988-03-17 |
Family
ID=11713182
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP917380A Granted JPS56108767A (en) | 1980-01-28 | 1980-01-28 | Bismoranoline derivative |
Country Status (7)
Country | Link |
---|---|
US (1) | US4336373A (en, 2012) |
JP (1) | JPS56108767A (en, 2012) |
CH (1) | CH643830A5 (en, 2012) |
DE (1) | DE3102769A1 (en, 2012) |
FR (1) | FR2474498B1 (en, 2012) |
GB (1) | GB2067989B (en, 2012) |
IT (1) | IT1170641B (en, 2012) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112441963A (zh) * | 2019-08-29 | 2021-03-05 | 南京理工大学 | 二价态dnj衍生物、合成方法及其应用 |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2922760A1 (de) * | 1979-06-05 | 1980-12-11 | Bayer Ag | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung |
GB2181729B (en) * | 1985-10-12 | 1990-04-04 | Nippon Shinyaku Co Ltd | Glucosylmoranoline derivatives and production thereof |
JPS62242692A (ja) * | 1986-04-15 | 1987-10-23 | Nippon Shinyaku Co Ltd | モラノリン誘導体の製造法 |
JP2504000B2 (ja) * | 1986-09-02 | 1996-06-05 | 日本新薬株式会社 | グルコシルモラノリン誘導体 |
GB8827701D0 (en) * | 1987-12-09 | 1988-12-29 | Nippon Shinyaku Co Ltd | Thrombolytic &c compositions |
US5192772A (en) * | 1987-12-09 | 1993-03-09 | Nippon Shinyaku Co. Ltd. | Therapeutic agents |
US5536732A (en) * | 1990-04-27 | 1996-07-16 | Merrell Pharmaceuticals Inc. | N-derivatives of 1-deoxy nojirimycin |
US5252587A (en) * | 1990-04-27 | 1993-10-12 | Merrell Dow Pharmaceuticals, Inc. | N-derivatives of 1-deoxy nojirimycin |
EP1575587A1 (en) * | 2002-10-29 | 2005-09-21 | Ranbaxy Laboratories, Ltd. | Iminosugar derivatives as glucosidase inhibitors |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1555654A (en) * | 1977-06-25 | 1979-11-14 | Exxon Research Engineering Co | Agricultural burner apparatus |
NO154918C (no) * | 1977-08-27 | 1987-01-14 | Bayer Ag | Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin. |
JPS5943946B2 (ja) * | 1978-04-28 | 1984-10-25 | 日本新薬株式会社 | N−アルケニルモラノリン誘導体 |
DE2830469A1 (de) * | 1978-07-11 | 1980-01-24 | Bayer Ag | Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten |
DE2922760A1 (de) * | 1979-06-05 | 1980-12-11 | Bayer Ag | Neue derivate von 3,4,5-trihydroxypiperidin, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel sowie in der tierernaehrung |
DE2925943A1 (de) * | 1979-06-27 | 1981-01-29 | Bayer Ag | 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
-
1980
- 1980-01-28 JP JP917380A patent/JPS56108767A/ja active Granted
-
1981
- 1981-01-06 GB GB8100185A patent/GB2067989B/en not_active Expired
- 1981-01-21 IT IT47608/81A patent/IT1170641B/it active
- 1981-01-27 CH CH51481A patent/CH643830A5/de not_active IP Right Cessation
- 1981-01-27 FR FR8101520A patent/FR2474498B1/fr not_active Expired
- 1981-01-28 DE DE19813102769 patent/DE3102769A1/de not_active Ceased
- 1981-03-26 US US06/247,885 patent/US4336373A/en not_active Expired - Fee Related
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN112441963A (zh) * | 2019-08-29 | 2021-03-05 | 南京理工大学 | 二价态dnj衍生物、合成方法及其应用 |
CN112441963B (zh) * | 2019-08-29 | 2023-01-03 | 南京理工大学 | 二价态dnj衍生物、合成方法及其应用 |
Also Published As
Publication number | Publication date |
---|---|
IT1170641B (it) | 1987-06-03 |
IT8147608A0 (it) | 1981-01-21 |
DE3102769A1 (de) | 1982-02-04 |
FR2474498B1 (fr) | 1986-09-26 |
US4336373A (en) | 1982-06-22 |
GB2067989B (en) | 1984-01-25 |
GB2067989A (en) | 1981-08-05 |
FR2474498A1 (fr) | 1981-07-31 |
JPS6312063B2 (en, 2012) | 1988-03-17 |
CH643830A5 (de) | 1984-06-29 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IE40858B1 (en) | New benzimidazole derivatives,their preparation,and their use in affecting gastric acid secretion | |
JPS56108767A (en) | Bismoranoline derivative | |
US4191776A (en) | Biphenyl derivatives | |
JPS56147746A (en) | Quinones and their preparation | |
IE44211L (en) | Acylamino (alkyl) benzenes. | |
JPS5598163A (en) | Cinnamylmoranoline derivative | |
FR2369288A1 (fr) | Procede de preparation de composes organiques d'etain | |
JPS56108768A (en) | Cinnamylmoranoline derivative | |
JPS5585520A (en) | Remedy for peptic ulcer | |
JPS56123932A (en) | Preparation of 4-hydroxycyclopentenone | |
IE43501L (en) | Hydroxyacids. | |
JPS5640669A (en) | Imidazole derivative and its preparation | |
JPS5592343A (en) | Preparation of optically active substituted isovaleric acid | |
JPS5520740A (en) | Aminoalkoxybibenzyl and its acid addition salt | |
JPS5489037A (en) | Anti-ulcer agent | |
FR2449680A1 (fr) | Analogues de la prostaglandine i2 et compositions pharmaceutiques les contenant | |
FR2365569A1 (fr) | Nouveaux acides carboxyliques pyrimido (1,2a)-heterocycliques, procede de preparation de ces corps et compositions pharmaceutiques qui les contiennent | |
JPS5598200A (en) | Preparation of 24xi, 25-dihydroxycholesta-1,4,6-trien-3-one | |
JPS559051A (en) | Substituted moranoline derivative | |
JPS55143960A (en) | Novel acetal compound and its preparation | |
JPS5515419A (en) | Novel oxabicyclo(3,2,1)-octane derivative and its preparation | |
JPS5728038A (en) | Octadecenoic acid amide | |
JPS5770884A (en) | Novel piperidine derivative and its preparation | |
JPS5728061A (en) | Pyridazinone derivative | |
FR2379505A1 (fr) | Nouveaux produits doues notamment de proprietes therapeutiques, leurs procedes de preparation, et medicaments a base de ces produits |