JPS5592349A - New cyclohexane derivative - Google Patents
New cyclohexane derivativeInfo
- Publication number
- JPS5592349A JPS5592349A JP16531878A JP16531878A JPS5592349A JP S5592349 A JPS5592349 A JP S5592349A JP 16531878 A JP16531878 A JP 16531878A JP 16531878 A JP16531878 A JP 16531878A JP S5592349 A JPS5592349 A JP S5592349A
- Authority
- JP
- Japan
- Prior art keywords
- action
- compounds
- formula
- formulae
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
NEW MATERIAL:New cyclohexane derivatives of formula I (R1 is cyano or carbamoyl; R2 is H or OH).
EXAMPLE: 1-Methyl-4-isobexylcyclohexanecarbonitrile.
USE: Medicines having pharmacological actions, such as antiallergic action, antitumorigenic action, antirheumatic action and anti-inflammatory action, and their intermediates.
PROCESS: Compounds of formula I are obtained as follows: (1) preparation of compounds of formulae X and III according to a reaction formula, (2) catalytic hydrogenation of the compounds of formulae II and III in an alcohol in the presence of platinum oxide or palladium on carbon, and if necessary, (3) hydrolysis of the product with hydrochloric acid, potassium hydroxide, sodium hydroxide, etc, in an alcohol solvent in the presence of hydrogen peroxide.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16531878A JPS5949220B2 (en) | 1978-12-29 | 1978-12-29 | Novel cyclohexane derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16531878A JPS5949220B2 (en) | 1978-12-29 | 1978-12-29 | Novel cyclohexane derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5592349A true JPS5592349A (en) | 1980-07-12 |
JPS5949220B2 JPS5949220B2 (en) | 1984-12-01 |
Family
ID=15810043
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP16531878A Expired JPS5949220B2 (en) | 1978-12-29 | 1978-12-29 | Novel cyclohexane derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5949220B2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140349901A1 (en) * | 2013-05-23 | 2014-11-27 | Kao Corporation | 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile |
-
1978
- 1978-12-29 JP JP16531878A patent/JPS5949220B2/en not_active Expired
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20140349901A1 (en) * | 2013-05-23 | 2014-11-27 | Kao Corporation | 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile |
JP2014227385A (en) * | 2013-05-23 | 2014-12-08 | 花王株式会社 | 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile |
US8980819B2 (en) * | 2013-05-23 | 2015-03-17 | Kao Corporation | 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile |
Also Published As
Publication number | Publication date |
---|---|
JPS5949220B2 (en) | 1984-12-01 |
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