JPS5592349A - New cyclohexane derivative - Google Patents

New cyclohexane derivative

Info

Publication number
JPS5592349A
JPS5592349A JP16531878A JP16531878A JPS5592349A JP S5592349 A JPS5592349 A JP S5592349A JP 16531878 A JP16531878 A JP 16531878A JP 16531878 A JP16531878 A JP 16531878A JP S5592349 A JPS5592349 A JP S5592349A
Authority
JP
Japan
Prior art keywords
action
compounds
formula
formulae
new
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP16531878A
Other languages
Japanese (ja)
Other versions
JPS5949220B2 (en
Inventor
Kanji Noda
Akira Nakagawa
Munehiko Hirano
Kenji Yamagata
Yoichi Nakajima
Terumi Yatani
Hiroyuki Ide
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hisamitsu Pharmaceutical Co Inc
Original Assignee
Hisamitsu Pharmaceutical Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hisamitsu Pharmaceutical Co Inc filed Critical Hisamitsu Pharmaceutical Co Inc
Priority to JP16531878A priority Critical patent/JPS5949220B2/en
Publication of JPS5592349A publication Critical patent/JPS5592349A/en
Publication of JPS5949220B2 publication Critical patent/JPS5949220B2/en
Expired legal-status Critical Current

Links

Landscapes

  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:New cyclohexane derivatives of formula I (R1 is cyano or carbamoyl; R2 is H or OH).
EXAMPLE: 1-Methyl-4-isobexylcyclohexanecarbonitrile.
USE: Medicines having pharmacological actions, such as antiallergic action, antitumorigenic action, antirheumatic action and anti-inflammatory action, and their intermediates.
PROCESS: Compounds of formula I are obtained as follows: (1) preparation of compounds of formulae X and III according to a reaction formula, (2) catalytic hydrogenation of the compounds of formulae II and III in an alcohol in the presence of platinum oxide or palladium on carbon, and if necessary, (3) hydrolysis of the product with hydrochloric acid, potassium hydroxide, sodium hydroxide, etc, in an alcohol solvent in the presence of hydrogen peroxide.
COPYRIGHT: (C)1980,JPO&Japio
JP16531878A 1978-12-29 1978-12-29 Novel cyclohexane derivative Expired JPS5949220B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16531878A JPS5949220B2 (en) 1978-12-29 1978-12-29 Novel cyclohexane derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16531878A JPS5949220B2 (en) 1978-12-29 1978-12-29 Novel cyclohexane derivative

Publications (2)

Publication Number Publication Date
JPS5592349A true JPS5592349A (en) 1980-07-12
JPS5949220B2 JPS5949220B2 (en) 1984-12-01

Family

ID=15810043

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16531878A Expired JPS5949220B2 (en) 1978-12-29 1978-12-29 Novel cyclohexane derivative

Country Status (1)

Country Link
JP (1) JPS5949220B2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140349901A1 (en) * 2013-05-23 2014-11-27 Kao Corporation 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140349901A1 (en) * 2013-05-23 2014-11-27 Kao Corporation 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile
JP2014227385A (en) * 2013-05-23 2014-12-08 花王株式会社 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile
US8980819B2 (en) * 2013-05-23 2015-03-17 Kao Corporation 4(3)-(4-hydroxy-4-methylpentyl)-3-cyclohexene-1-carbonitrile

Also Published As

Publication number Publication date
JPS5949220B2 (en) 1984-12-01

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