JPS5513227A - Production of 2-(2,6-dichloroanilino)phenyl acetic acid - Google Patents

Production of 2-(2,6-dichloroanilino)phenyl acetic acid

Info

Publication number
JPS5513227A
JPS5513227A JP8591978A JP8591978A JPS5513227A JP S5513227 A JPS5513227 A JP S5513227A JP 8591978 A JP8591978 A JP 8591978A JP 8591978 A JP8591978 A JP 8591978A JP S5513227 A JPS5513227 A JP S5513227A
Authority
JP
Japan
Prior art keywords
compound
formula
acid
dichloroanilino
acetic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8591978A
Other languages
Japanese (ja)
Inventor
Fujio Nohara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IKEDA MOHANDO CO
IKEDA MOHANDOU KK
Original Assignee
IKEDA MOHANDO CO
IKEDA MOHANDOU KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IKEDA MOHANDO CO, IKEDA MOHANDOU KK filed Critical IKEDA MOHANDO CO
Priority to JP8591978A priority Critical patent/JPS5513227A/en
Publication of JPS5513227A publication Critical patent/JPS5513227A/en
Pending legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PURPOSE: The catalytic reduction of 2-(2,6-dichloroanilino)phenylglycolic acid is effected in the presence of a catalyst under acidic conditions to produce with industrial safety title compound used as nonsteroidal anti-inflammatory analgesic.
CONSTITUTION: The compound of formula I is hydrogenated in a lower aliphatic acid, preferably acetic acid, containing a mineral acid, preferably sulfuric acid, in the presence of a noble metal catalyst, preferably palldium on carbon, under normal pressure to 80 atmospheric pressure, preferably 30-50 atmospheric pressure, to give the objective compound of formula II. The compound of formula I is obtained from the compound of formula III through similar reactions to the above and the compound of formula III is prepraed by the hydrolysis of the compound of formula IV with 1.2W3 moles of alkali, preferably caustic soda, in an organic solvent as ethanol under heating.
COPYRIGHT: (C)1980,JPO&Japio
JP8591978A 1978-07-14 1978-07-14 Production of 2-(2,6-dichloroanilino)phenyl acetic acid Pending JPS5513227A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP8591978A JPS5513227A (en) 1978-07-14 1978-07-14 Production of 2-(2,6-dichloroanilino)phenyl acetic acid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP8591978A JPS5513227A (en) 1978-07-14 1978-07-14 Production of 2-(2,6-dichloroanilino)phenyl acetic acid

Publications (1)

Publication Number Publication Date
JPS5513227A true JPS5513227A (en) 1980-01-30

Family

ID=13872187

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8591978A Pending JPS5513227A (en) 1978-07-14 1978-07-14 Production of 2-(2,6-dichloroanilino)phenyl acetic acid

Country Status (1)

Country Link
JP (1) JPS5513227A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5687117A (en) * 1979-12-19 1981-07-15 Fujitsu Ltd Switching regulator
JPS5947940A (en) * 1982-09-10 1984-03-17 株式会社明電舎 Chopper type charger

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5412342A (en) * 1977-06-29 1979-01-30 Iwaki Seiyaku Kk Process for preparing oo*nnarylamino*phenyacetate derivative

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5412342A (en) * 1977-06-29 1979-01-30 Iwaki Seiyaku Kk Process for preparing oo*nnarylamino*phenyacetate derivative

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5687117A (en) * 1979-12-19 1981-07-15 Fujitsu Ltd Switching regulator
JPS6337408B2 (en) * 1979-12-19 1988-07-25 Fujitsu Ltd
JPS5947940A (en) * 1982-09-10 1984-03-17 株式会社明電舎 Chopper type charger

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