JPS6470431A - 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal - Google Patents

1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal

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Publication number
JPS6470431A
JPS6470431A JP18017288A JP18017288A JPS6470431A JP S6470431 A JPS6470431 A JP S6470431A JP 18017288 A JP18017288 A JP 18017288A JP 18017288 A JP18017288 A JP 18017288A JP S6470431 A JPS6470431 A JP S6470431A
Authority
JP
Japan
Prior art keywords
formula
compound
naphthyl
methoxy
acetal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP18017288A
Other languages
Japanese (ja)
Other versions
JPH0341456B2 (en
Inventor
Genichi Dobashi
Shuichi Mitamura
Atsuji Kitajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP18017288A priority Critical patent/JPS6470431A/en
Publication of JPS6470431A publication Critical patent/JPS6470431A/en
Publication of JPH0341456B2 publication Critical patent/JPH0341456B2/ja
Granted legal-status Critical Current

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

NEW MATERIAL:The compound of formula I [R<1>-R<3> are lower alkyl; Y is H or group of formula II (R is aromatic group, or substituted or unsubstituted alkyl); R<1> and R<2> may together form a cyclic acetal]. EXAMPLE:1-(6-Methoxy-2-naphthyl)-2-hydroxy-1-propanone dimethylacetal. USE:An intermediate for safely producing alpha-(6-methoxy-2-naphthyl)propionic acid useful as an anti-inflammatory agent and analgesic agent in high yield and purity in a short time. PREPARATION:The compound of formula Ia is produced by reacting a compound of formula III (X is halogen) with a compound of formula R<1>OM (M is alkalis metal) in the presence of a compound of formula R<1>OH. The product can be converted to a compound of formula Ib by reacting with an O- sulfonylation agent. The above medicine of formula IV (R<4> is H or lower alkyl) can be easily produced by the hydrolysis of the compound of formula Ib.
JP18017288A 1988-07-21 1988-07-21 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal Granted JPS6470431A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP18017288A JPS6470431A (en) 1988-07-21 1988-07-21 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP18017288A JPS6470431A (en) 1988-07-21 1988-07-21 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal

Publications (2)

Publication Number Publication Date
JPS6470431A true JPS6470431A (en) 1989-03-15
JPH0341456B2 JPH0341456B2 (en) 1991-06-24

Family

ID=16078654

Family Applications (1)

Application Number Title Priority Date Filing Date
JP18017288A Granted JPS6470431A (en) 1988-07-21 1988-07-21 1-(6-methoxy-2-naphthyl)-2-oxy-1-alkanone acetal

Country Status (1)

Country Link
JP (1) JPS6470431A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020517590A (en) * 2017-04-24 2020-06-18 アイジーエム グループ ビー．ヴィ． A convenient oxidative functionalization of alkyl aryl ketones.

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020517590A (en) * 2017-04-24 2020-06-18 アイジーエム グループ ビー．ヴィ． A convenient oxidative functionalization of alkyl aryl ketones.
US11203580B2 (en) 2017-04-24 2021-12-21 Igm Group B.V. Simple oxidative functionalized of alkyl aryl ketones

Also Published As

Publication number Publication date
JPH0341456B2 (en) 1991-06-24

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