JPS5780380A - Alpha-oxyalkanothienone acetal - Google Patents

Alpha-oxyalkanothienone acetal

Info

Publication number
JPS5780380A
JPS5780380A JP15518580A JP15518580A JPS5780380A JP S5780380 A JPS5780380 A JP S5780380A JP 15518580 A JP15518580 A JP 15518580A JP 15518580 A JP15518580 A JP 15518580A JP S5780380 A JPS5780380 A JP S5780380A
Authority
JP
Japan
Prior art keywords
formula
compound
acetal
thienyl
oxyalkanothienone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP15518580A
Other languages
Japanese (ja)
Inventor
Genichi Dobashi
Shuichi Mitamura
Atsuji Kitajima
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP15518580A priority Critical patent/JPS5780380A/en
Publication of JPS5780380A publication Critical patent/JPS5780380A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:An α-oxyalkanothienone acetal of formula I[R1, R2 and R3 are lower alkyl; Y is H or formula II (R is aromatic group or substituted or unsubstituted alkyl) or R1 and R2 together form a cyclic acetal].
EXAMPLE: 1-(2-Thienyl)-2-hydroxyl-1-propanone dimethyl acetal.
USE: A raw material for a compound useful as a synthetic intermediate for medicines, particularly capable of easily giving an α-(5-benzoly-2-thienyl)propionic acid having anti-inflammatory and analgesic actions by reacting an α-(2-thienyl) propionic acid which is an intermediate therefor with benzoyl chloride in the presence of a Lewis acid.
PROCESS: An α-haloketone of formula III (X is halogen) is reacted with a compound of the formula R1OM (M is alkaline metallic atom) in the presence of an alcohol to give the compound of formula IV which is the compound of formula I (Y is H).
COPYRIGHT: (C)1982,JPO&Japio
JP15518580A 1980-11-06 1980-11-06 Alpha-oxyalkanothienone acetal Pending JPS5780380A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP15518580A JPS5780380A (en) 1980-11-06 1980-11-06 Alpha-oxyalkanothienone acetal

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP15518580A JPS5780380A (en) 1980-11-06 1980-11-06 Alpha-oxyalkanothienone acetal

Publications (1)

Publication Number Publication Date
JPS5780380A true JPS5780380A (en) 1982-05-19

Family

ID=15600334

Family Applications (1)

Application Number Title Priority Date Filing Date
JP15518580A Pending JPS5780380A (en) 1980-11-06 1980-11-06 Alpha-oxyalkanothienone acetal

Country Status (1)

Country Link
JP (1) JPS5780380A (en)

Similar Documents

Publication Publication Date Title
JPS5780380A (en) Alpha-oxyalkanothienone acetal
JPS5576871A (en) Chromanyloxy fatty acid homolog
JPS5535066A (en) Novel pyrazole derivative
JPS5461159A (en) Alpha-thio-alpha-(acylphenyl) carboxylic acid derivatives
JPS5424888A (en) Novel 7alpha-methoxycephalosporins and their preparation
JPS5553281A (en) Acylaminoacetal
JPS5585568A (en) Quinolinone-imine derivative and its preparation
JPS5639074A (en) Pyrimidine derivative
JPS54144320A (en) Preparation of ureidomethylene malonic ester
JPS5772963A (en) Alpha-(2-pyridyl)arylacetaldehyde
JPS6468A (en) Tertiary amino-alcohol compound and production of optically active secondary alcohol using said compound
JPS5770883A (en) (2-thienylseleno)acetic acid and its preparation
JPS5555168A (en) Novel 4-carboxy-2-phenyl-1-phthalazone derivative
JPS54119428A (en) Novel benzoic acid derivative
JPS5515407A (en) 2-phenyl substituted 1-phthalazone derivative
JPS5555169A (en) Novel 4-hydroxymethyl-2-phenyl-1-phthalazone derivative
JPS56164144A (en) Preparation of novel aryloxyacid derivative
JPS5481253A (en) 2-methyl-2-hydroxyperhydrotriquinacene
JPS52102274A (en) 8-azaprostanic acid derivatives
JPS5513242A (en) N-isobutylamide derivative
JPS54128596A (en) Novel heptanoic ester and its preparation
JPS5441867A (en) Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation
JPS56135462A (en) Preparation of alpha-sulfenylacetic acid and aromatic compound having related functional group
JPS5511501A (en) Novel 7-methoxycephalosporin
JPS5412356A (en) Novel 2-(2-fluoro-4-biphenyl)-propionic acid ester derivatives