JPS5780380A - Alpha-oxyalkanothienone acetal - Google Patents
Alpha-oxyalkanothienone acetalInfo
- Publication number
- JPS5780380A JPS5780380A JP15518580A JP15518580A JPS5780380A JP S5780380 A JPS5780380 A JP S5780380A JP 15518580 A JP15518580 A JP 15518580A JP 15518580 A JP15518580 A JP 15518580A JP S5780380 A JPS5780380 A JP S5780380A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- acetal
- thienyl
- oxyalkanothienone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:An α-oxyalkanothienone acetal of formula I[R1, R2 and R3 are lower alkyl; Y is H or formula II (R is aromatic group or substituted or unsubstituted alkyl) or R1 and R2 together form a cyclic acetal].
EXAMPLE: 1-(2-Thienyl)-2-hydroxyl-1-propanone dimethyl acetal.
USE: A raw material for a compound useful as a synthetic intermediate for medicines, particularly capable of easily giving an α-(5-benzoly-2-thienyl)propionic acid having anti-inflammatory and analgesic actions by reacting an α-(2-thienyl) propionic acid which is an intermediate therefor with benzoyl chloride in the presence of a Lewis acid.
PROCESS: An α-haloketone of formula III (X is halogen) is reacted with a compound of the formula R1OM (M is alkaline metallic atom) in the presence of an alcohol to give the compound of formula IV which is the compound of formula I (Y is H).
COPYRIGHT: (C)1982,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15518580A JPS5780380A (en) | 1980-11-06 | 1980-11-06 | Alpha-oxyalkanothienone acetal |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15518580A JPS5780380A (en) | 1980-11-06 | 1980-11-06 | Alpha-oxyalkanothienone acetal |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS5780380A true JPS5780380A (en) | 1982-05-19 |
Family
ID=15600334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP15518580A Pending JPS5780380A (en) | 1980-11-06 | 1980-11-06 | Alpha-oxyalkanothienone acetal |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5780380A (en) |
-
1980
- 1980-11-06 JP JP15518580A patent/JPS5780380A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5780380A (en) | Alpha-oxyalkanothienone acetal | |
JPS5576871A (en) | Chromanyloxy fatty acid homolog | |
JPS5535066A (en) | Novel pyrazole derivative | |
JPS5461159A (en) | Alpha-thio-alpha-(acylphenyl) carboxylic acid derivatives | |
JPS5424888A (en) | Novel 7alpha-methoxycephalosporins and their preparation | |
JPS5553281A (en) | Acylaminoacetal | |
JPS5585568A (en) | Quinolinone-imine derivative and its preparation | |
JPS5639074A (en) | Pyrimidine derivative | |
JPS54144320A (en) | Preparation of ureidomethylene malonic ester | |
JPS5772963A (en) | Alpha-(2-pyridyl)arylacetaldehyde | |
JPS6468A (en) | Tertiary amino-alcohol compound and production of optically active secondary alcohol using said compound | |
JPS5770883A (en) | (2-thienylseleno)acetic acid and its preparation | |
JPS5555168A (en) | Novel 4-carboxy-2-phenyl-1-phthalazone derivative | |
JPS54119428A (en) | Novel benzoic acid derivative | |
JPS5515407A (en) | 2-phenyl substituted 1-phthalazone derivative | |
JPS5555169A (en) | Novel 4-hydroxymethyl-2-phenyl-1-phthalazone derivative | |
JPS56164144A (en) | Preparation of novel aryloxyacid derivative | |
JPS5481253A (en) | 2-methyl-2-hydroxyperhydrotriquinacene | |
JPS52102274A (en) | 8-azaprostanic acid derivatives | |
JPS5513242A (en) | N-isobutylamide derivative | |
JPS54128596A (en) | Novel heptanoic ester and its preparation | |
JPS5441867A (en) | Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation | |
JPS56135462A (en) | Preparation of alpha-sulfenylacetic acid and aromatic compound having related functional group | |
JPS5511501A (en) | Novel 7-methoxycephalosporin | |
JPS5412356A (en) | Novel 2-(2-fluoro-4-biphenyl)-propionic acid ester derivatives |