JPS5441867A - Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation - Google Patents
Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparationInfo
- Publication number
- JPS5441867A JPS5441867A JP10682677A JP10682677A JPS5441867A JP S5441867 A JPS5441867 A JP S5441867A JP 10682677 A JP10682677 A JP 10682677A JP 10682677 A JP10682677 A JP 10682677A JP S5441867 A JPS5441867 A JP S5441867A
- Authority
- JP
- Japan
- Prior art keywords
- thienyl
- alpha
- compound
- formula
- thio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Abstract
NEW MATERIAL:α-Thio-α-(2-thienyl)alkanoic acid derivatives of formulaI(R1, R2 are H, halogen, lower alkyl: R3 is alkyl, aryl: R is H, lower alkyl).
EXAMPLE: α-Phenylthio-thiophene-2-acetic acid.
USE: Intermediates of thioprophenic acid, and antiflammatory agent, and α-(2-thienyl) alkanoic esters, strong insectides of new pyrethroxide.
PREPARATION: A compound of formula II is condensed with a haloform and a compound of formula III to form the objective compound of formula Iin which R is H and then, when necessary, a conventional alkylating agent of formula IV (X is I, Br) is reacted with the resulting product in the presence of at least 2 moles of a base to a compound of formulaIin which R is lower alkyl. The reduction of said compound gives α-(2-thienyl)-alkanoic acid.
COPYRIGHT: (C)1979,JPO&Japio
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10682677A JPS5441867A (en) | 1977-09-07 | 1977-09-07 | Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation |
GB7833298A GB2007220B (en) | 1977-08-18 | 1978-08-14 | Process for preparing 2-thio-2-substituted alkanoic acid dricatives |
US05/934,553 US4245108A (en) | 1977-08-18 | 1978-08-17 | Process for preparing 2-thio-2-substituted-alkanoic acid derivatives |
DE19782836257 DE2836257A1 (en) | 1977-08-18 | 1978-08-18 | PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 2-THIOALCANIC ACID DERIVATIVES |
FR7824142A FR2400507A1 (en) | 1977-08-18 | 1978-08-18 | PROCESS FOR PREPARING 2-THIOALCANOIC ACID DERIVATIVES SUBSTITUTED IN POSITION 2 |
CA309,676A CA1103684A (en) | 1977-08-18 | 1978-08-18 | Process for preparing 2-thio-2-substituted-alkanoic acid derivatives |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10682677A JPS5441867A (en) | 1977-09-07 | 1977-09-07 | Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS5441867A true JPS5441867A (en) | 1979-04-03 |
JPS5538348B2 JPS5538348B2 (en) | 1980-10-03 |
Family
ID=14443566
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP10682677A Granted JPS5441867A (en) | 1977-08-18 | 1977-09-07 | Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS5441867A (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52106862A (en) * | 1976-03-04 | 1977-09-07 | Sagami Chem Res Center | Furyl-or thienyl-acetic acids having sulfur-containing functional grou ps at alpha-position |
-
1977
- 1977-09-07 JP JP10682677A patent/JPS5441867A/en active Granted
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS52106862A (en) * | 1976-03-04 | 1977-09-07 | Sagami Chem Res Center | Furyl-or thienyl-acetic acids having sulfur-containing functional grou ps at alpha-position |
Also Published As
Publication number | Publication date |
---|---|
JPS5538348B2 (en) | 1980-10-03 |
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