JPS5441867A - Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation - Google Patents

Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation

Info

Publication number
JPS5441867A
JPS5441867A JP10682677A JP10682677A JPS5441867A JP S5441867 A JPS5441867 A JP S5441867A JP 10682677 A JP10682677 A JP 10682677A JP 10682677 A JP10682677 A JP 10682677A JP S5441867 A JPS5441867 A JP S5441867A
Authority
JP
Japan
Prior art keywords
thienyl
alpha
compound
formula
thio
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10682677A
Other languages
Japanese (ja)
Other versions
JPS5538348B2 (en
Inventor
Sei Kondo
Minoru Suda
Daiei Tsunemoto
Akira Negishi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sagami Chemical Research Institute
Original Assignee
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sagami Chemical Research Institute filed Critical Sagami Chemical Research Institute
Priority to JP10682677A priority Critical patent/JPS5441867A/en
Priority to GB7833298A priority patent/GB2007220B/en
Priority to US05/934,553 priority patent/US4245108A/en
Priority to DE19782836257 priority patent/DE2836257A1/en
Priority to FR7824142A priority patent/FR2400507A1/en
Priority to CA309,676A priority patent/CA1103684A/en
Publication of JPS5441867A publication Critical patent/JPS5441867A/en
Publication of JPS5538348B2 publication Critical patent/JPS5538348B2/ja
Granted legal-status Critical Current

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  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)

Abstract

NEW MATERIAL:α-Thio-α-(2-thienyl)alkanoic acid derivatives of formulaI(R1, R2 are H, halogen, lower alkyl: R3 is alkyl, aryl: R is H, lower alkyl).
EXAMPLE: α-Phenylthio-thiophene-2-acetic acid.
USE: Intermediates of thioprophenic acid, and antiflammatory agent, and α-(2-thienyl) alkanoic esters, strong insectides of new pyrethroxide.
PREPARATION: A compound of formula II is condensed with a haloform and a compound of formula III to form the objective compound of formula Iin which R is H and then, when necessary, a conventional alkylating agent of formula IV (X is I, Br) is reacted with the resulting product in the presence of at least 2 moles of a base to a compound of formulaIin which R is lower alkyl. The reduction of said compound gives α-(2-thienyl)-alkanoic acid.
COPYRIGHT: (C)1979,JPO&Japio
JP10682677A 1977-08-18 1977-09-07 Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation Granted JPS5441867A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP10682677A JPS5441867A (en) 1977-09-07 1977-09-07 Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation
GB7833298A GB2007220B (en) 1977-08-18 1978-08-14 Process for preparing 2-thio-2-substituted alkanoic acid dricatives
US05/934,553 US4245108A (en) 1977-08-18 1978-08-17 Process for preparing 2-thio-2-substituted-alkanoic acid derivatives
DE19782836257 DE2836257A1 (en) 1977-08-18 1978-08-18 PROCESS FOR THE PRODUCTION OF 2-SUBSTITUTED 2-THIOALCANIC ACID DERIVATIVES
FR7824142A FR2400507A1 (en) 1977-08-18 1978-08-18 PROCESS FOR PREPARING 2-THIOALCANOIC ACID DERIVATIVES SUBSTITUTED IN POSITION 2
CA309,676A CA1103684A (en) 1977-08-18 1978-08-18 Process for preparing 2-thio-2-substituted-alkanoic acid derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10682677A JPS5441867A (en) 1977-09-07 1977-09-07 Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5441867A true JPS5441867A (en) 1979-04-03
JPS5538348B2 JPS5538348B2 (en) 1980-10-03

Family

ID=14443566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10682677A Granted JPS5441867A (en) 1977-08-18 1977-09-07 Alpha-thio--alpha(2-thienyl)alkanoic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5441867A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106862A (en) * 1976-03-04 1977-09-07 Sagami Chem Res Center Furyl-or thienyl-acetic acids having sulfur-containing functional grou ps at alpha-position

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS52106862A (en) * 1976-03-04 1977-09-07 Sagami Chem Res Center Furyl-or thienyl-acetic acids having sulfur-containing functional grou ps at alpha-position

Also Published As

Publication number Publication date
JPS5538348B2 (en) 1980-10-03

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