JPS5527163A - Tetrahydroxanthene-2-carboxylic derivative - Google Patents

Tetrahydroxanthene-2-carboxylic derivative

Info

Publication number
JPS5527163A
JPS5527163A JP10037278A JP10037278A JPS5527163A JP S5527163 A JPS5527163 A JP S5527163A JP 10037278 A JP10037278 A JP 10037278A JP 10037278 A JP10037278 A JP 10037278A JP S5527163 A JPS5527163 A JP S5527163A
Authority
JP
Japan
Prior art keywords
formula
compound
tetrahydroxanthene
antiallergic
cooh
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP10037278A
Other languages
Japanese (ja)
Other versions
JPS625153B2 (en
Inventor
Kazuhiro Onoki
Hisashi Kunieda
Kiyoshi Kawamura
Naoki Machida
Shozo Shirato
Masahiko Nagakura
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kowa Co Ltd
Original Assignee
Kowa Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kowa Co Ltd filed Critical Kowa Co Ltd
Priority to JP10037278A priority Critical patent/JPS5527163A/en
Publication of JPS5527163A publication Critical patent/JPS5527163A/en
Publication of JPS625153B2 publication Critical patent/JPS625153B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Pyrane Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

NEW MATERIAL:Compounds of formula I (R1 is H, NO2, COOH, CN; R2 is H, lower alkyl; where both R1 and R2 are not H at a time).
EXAMPLE: 7-Nitro-1,2,3,4-tetrahydro-9-oxoxanthene-2-carboxylic methyl ester.
USE: Antiallergic, anti-inflammatory, analgesic and inhibitor against PCA reaction. Synthetic intermediate of antiallergic and antiasthamtic.
PREPARATION: The acylation of a compound of formula II (R3 is halogen, H) gives a compound of formula III (R4 is lower alkyl). The product or its reactive derivative is made to react with a compound of formula IV to form a compound of formula Ia, which is, when necessary, converted into the compound of formula I where R1 is NO2, CN, or COOH.
COPYRIGHT: (C)1980,JPO&Japio
JP10037278A 1978-08-17 1978-08-17 Tetrahydroxanthene-2-carboxylic derivative Granted JPS5527163A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP10037278A JPS5527163A (en) 1978-08-17 1978-08-17 Tetrahydroxanthene-2-carboxylic derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10037278A JPS5527163A (en) 1978-08-17 1978-08-17 Tetrahydroxanthene-2-carboxylic derivative

Publications (2)

Publication Number Publication Date
JPS5527163A true JPS5527163A (en) 1980-02-27
JPS625153B2 JPS625153B2 (en) 1987-02-03

Family

ID=14272202

Family Applications (1)

Application Number Title Priority Date Filing Date
JP10037278A Granted JPS5527163A (en) 1978-08-17 1978-08-17 Tetrahydroxanthene-2-carboxylic derivative

Country Status (1)

Country Link
JP (1) JPS5527163A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5239677A (en) * 1975-09-22 1977-03-28 Kowa Co Preparation of xanthene derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5239677A (en) * 1975-09-22 1977-03-28 Kowa Co Preparation of xanthene derivatives

Also Published As

Publication number Publication date
JPS625153B2 (en) 1987-02-03

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