JPS54128596A - Novel heptanoic ester and its preparation - Google Patents

Novel heptanoic ester and its preparation

Info

Publication number
JPS54128596A
JPS54128596A JP3636478A JP3636478A JPS54128596A JP S54128596 A JPS54128596 A JP S54128596A JP 3636478 A JP3636478 A JP 3636478A JP 3636478 A JP3636478 A JP 3636478A JP S54128596 A JPS54128596 A JP S54128596A
Authority
JP
Japan
Prior art keywords
formula
heptanoic
theobromine
ester
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP3636478A
Other languages
Japanese (ja)
Other versions
JPS5826914B2 (en
Inventor
Takanori Sone
Yukinari Kobayashi
Mikio Wakabayashi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Chemical Industry Co Ltd
Original Assignee
Asahi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Industry Co Ltd filed Critical Asahi Chemical Industry Co Ltd
Priority to JP3636478A priority Critical patent/JPS5826914B2/en
Publication of JPS54128596A publication Critical patent/JPS54128596A/en
Publication of JPS5826914B2 publication Critical patent/JPS5826914B2/en
Expired legal-status Critical Current

Links

Abstract

NEW MATERIAL:A heptanoic ester derivative of formula I: (R is 1W5C alkyl group).
EXAMPLE: 7-(Theobromin-1-yl)-3-oxo-heptanoic methyl ester.
USE: An intermediate for preparing 1-(5-oxohexyl)theobromine, which is a medicine having vesodilator and hematocytolysis actions with slight side effects.
PROCESS: A 1-(3-substituted-propyl)theobromine of formula II: (X is halogen, p- toluene sulfonyloxy) is reacted with dianions of acetoacetate of formula III: (M and M' are alkali metals) at a low temperature to give the desired compound of formula I. The compound of formula II can be obtained by reacting 1-(3-phenoxy-propyl) theobromine with a hydrohalogenic acid.
COPYRIGHT: (C)1979,JPO&Japio
JP3636478A 1978-03-29 1978-03-29 New heptanoic acid ester derivatives and their production method Expired JPS5826914B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP3636478A JPS5826914B2 (en) 1978-03-29 1978-03-29 New heptanoic acid ester derivatives and their production method

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP3636478A JPS5826914B2 (en) 1978-03-29 1978-03-29 New heptanoic acid ester derivatives and their production method

Publications (2)

Publication Number Publication Date
JPS54128596A true JPS54128596A (en) 1979-10-05
JPS5826914B2 JPS5826914B2 (en) 1983-06-06

Family

ID=12467769

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3636478A Expired JPS5826914B2 (en) 1978-03-29 1978-03-29 New heptanoic acid ester derivatives and their production method

Country Status (1)

Country Link
JP (1) JPS5826914B2 (en)

Also Published As

Publication number Publication date
JPS5826914B2 (en) 1983-06-06

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