JPS55143984A - Novel xanthine derivative - Google Patents

Novel xanthine derivative

Info

Publication number
JPS55143984A
JPS55143984A JP5051079A JP5051079A JPS55143984A JP S55143984 A JPS55143984 A JP S55143984A JP 5051079 A JP5051079 A JP 5051079A JP 5051079 A JP5051079 A JP 5051079A JP S55143984 A JPS55143984 A JP S55143984A
Authority
JP
Japan
Prior art keywords
formula
compound
solvent
xanthine derivative
novel xanthine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5051079A
Other languages
Japanese (ja)
Inventor
Nobunori Takemoto
Kenji Muto
Yoshihiro Nakamizo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KH Neochem Co Ltd
Original Assignee
Kyowa Hakko Kogyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyowa Hakko Kogyo Co Ltd filed Critical Kyowa Hakko Kogyo Co Ltd
Priority to JP5051079A priority Critical patent/JPS55143984A/en
Publication of JPS55143984A publication Critical patent/JPS55143984A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:1-(5-Oxo-3-hexenyl)-3,7-dimethylxanthine of formula I.
USE: Remedy for cardio-vasocular diseases, having vaso-dilating activity. Intermediate of pentoxifylline which is a useful known compound.
PROCESS: Reaction of a β-halo-propionaldehyde dialkyl acetal of formula II with 3,7- dimethyl xanthine of formula III in the presence of a base such as sodium hydroxide in a solvent such as water at 50W130°C, affords a compound of formula IV (R is 1W5C alkyl; X is halogen), which is made to react with isopropenyl acetate in the presence of a Lewis acid in a solvent such as dichloromethane at -70W+150°C to obtain the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
JP5051079A 1979-04-24 1979-04-24 Novel xanthine derivative Pending JPS55143984A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5051079A JPS55143984A (en) 1979-04-24 1979-04-24 Novel xanthine derivative

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5051079A JPS55143984A (en) 1979-04-24 1979-04-24 Novel xanthine derivative

Publications (1)

Publication Number Publication Date
JPS55143984A true JPS55143984A (en) 1980-11-10

Family

ID=12860951

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5051079A Pending JPS55143984A (en) 1979-04-24 1979-04-24 Novel xanthine derivative

Country Status (1)

Country Link
JP (1) JPS55143984A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60264085A (en) * 1984-06-11 1985-12-27 松下電器産業株式会社 Heater

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60264085A (en) * 1984-06-11 1985-12-27 松下電器産業株式会社 Heater
JPH0119753B2 (en) * 1984-06-11 1989-04-12 Matsushita Electric Ind Co Ltd

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