JPS55143984A - Novel xanthine derivative - Google Patents
Novel xanthine derivativeInfo
- Publication number
- JPS55143984A JPS55143984A JP5051079A JP5051079A JPS55143984A JP S55143984 A JPS55143984 A JP S55143984A JP 5051079 A JP5051079 A JP 5051079A JP 5051079 A JP5051079 A JP 5051079A JP S55143984 A JPS55143984 A JP S55143984A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- solvent
- xanthine derivative
- novel xanthine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:1-(5-Oxo-3-hexenyl)-3,7-dimethylxanthine of formula I.
USE: Remedy for cardio-vasocular diseases, having vaso-dilating activity. Intermediate of pentoxifylline which is a useful known compound.
PROCESS: Reaction of a β-halo-propionaldehyde dialkyl acetal of formula II with 3,7- dimethyl xanthine of formula III in the presence of a base such as sodium hydroxide in a solvent such as water at 50W130°C, affords a compound of formula IV (R is 1W5C alkyl; X is halogen), which is made to react with isopropenyl acetate in the presence of a Lewis acid in a solvent such as dichloromethane at -70W+150°C to obtain the compound of formula I.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5051079A JPS55143984A (en) | 1979-04-24 | 1979-04-24 | Novel xanthine derivative |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5051079A JPS55143984A (en) | 1979-04-24 | 1979-04-24 | Novel xanthine derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS55143984A true JPS55143984A (en) | 1980-11-10 |
Family
ID=12860951
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5051079A Pending JPS55143984A (en) | 1979-04-24 | 1979-04-24 | Novel xanthine derivative |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55143984A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60264085A (en) * | 1984-06-11 | 1985-12-27 | 松下電器産業株式会社 | Heater |
-
1979
- 1979-04-24 JP JP5051079A patent/JPS55143984A/en active Pending
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60264085A (en) * | 1984-06-11 | 1985-12-27 | 松下電器産業株式会社 | Heater |
JPH0119753B2 (en) * | 1984-06-11 | 1989-04-12 | Matsushita Electric Ind Co Ltd |
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