JPS56156280A - Theobromine derivative and its preparation - Google Patents
Theobromine derivative and its preparationInfo
- Publication number
- JPS56156280A JPS56156280A JP5951180A JP5951180A JPS56156280A JP S56156280 A JPS56156280 A JP S56156280A JP 5951180 A JP5951180 A JP 5951180A JP 5951180 A JP5951180 A JP 5951180A JP S56156280 A JPS56156280 A JP S56156280A
- Authority
- JP
- Japan
- Prior art keywords
- formula
- compound
- preparation
- theobromine
- give
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
NEW MATERIAL:Compounds of formula I [R is group of formula II (R1 is lower alkyl, aryl)].
EXAMPLE: 1-(5'-Ethylthio-5'-hexenyl)-3,7-dimethylxanthine.
USE: A precursor of pentoxyfylline.
PREPARATION: The reaction of a compound of formula III such as methyl 1-methylthioethylsulfoxide with another compound of formula IV (X and X' are halogen) such as 1,4-dibromobutane is conducted in the presence of a base such as lithium diisopropylamide in a solvent such as diethyl ether at -78W150°C to give a compound of formula V. The product is made to react with theobromine in the presence of a base such as sodium hydroxide in a solvent such as diethyl ether at -78W 150°C to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5951180A JPS56156280A (en) | 1980-05-07 | 1980-05-07 | Theobromine derivative and its preparation |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP5951180A JPS56156280A (en) | 1980-05-07 | 1980-05-07 | Theobromine derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
JPS56156280A true JPS56156280A (en) | 1981-12-02 |
Family
ID=13115349
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP5951180A Pending JPS56156280A (en) | 1980-05-07 | 1980-05-07 | Theobromine derivative and its preparation |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS56156280A (en) |
-
1980
- 1980-05-07 JP JP5951180A patent/JPS56156280A/en active Pending
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPS5432460A (en) | Cycloalkylidenemethylphenylacetic acid derivative and their preparation | |
JPS5795964A (en) | Preparation of 2-substituted-3(2h)-pyridazinone derivative | |
JPS57116074A (en) | Novel camptothecin derivative and its preparation | |
JPS57176982A (en) | Dioxolanylazetidinone compound, its preparation and use | |
JPS56156280A (en) | Theobromine derivative and its preparation | |
JPS5711981A (en) | Theobromine derivative and its preparation | |
JPS5731671A (en) | Preparation of homopiperazine derivative | |
JPS5762278A (en) | Theobromine derivative and its preparation | |
JPS5798284A (en) | Preparation of 1-(5-oxohexyl)-3,7-dimethylxanthine | |
JPS56127378A (en) | 2-alkoxyindolizine derivative and its preparation | |
JPS56156263A (en) | Carbostyril derivative | |
JPS5639074A (en) | Pyrimidine derivative | |
JPS5742643A (en) | 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol | |
JPS5566560A (en) | Quinolone derivative | |
JPS55143984A (en) | Novel xanthine derivative | |
JPS5714585A (en) | 1-cycloalkylmethylpiperazine derivative | |
JPS55115868A (en) | Beta,beta,beta-trihalo-alpha-hydroxyethyl substituted-2-aroyl pyrrole derivative | |
JPS5758890A (en) | Preparation of glucosylmoranoline derivative | |
JPS5285175A (en) | Amino-substituted propiophenone derivatives and medicaments containing same | |
JPS5625166A (en) | 5-fluorouracil derivative | |
JPS5262280A (en) | Preparation of novel butyrophenone derivatives | |
JPS56120669A (en) | Allophanoylpiperazine compound and analgesic agent containing the same as active constituent | |
JPS5495580A (en) | Isocarbostyril derivative | |
JPS5668673A (en) | Substituted methylidenehydrazinopyrimidine derivative and its preparation | |
JPS568385A (en) | 2-allyl-imidazo 1,2-a imidazole derivative |