JPS56156280A - Theobromine derivative and its preparation - Google Patents

Theobromine derivative and its preparation

Info

Publication number
JPS56156280A
JPS56156280A JP5951180A JP5951180A JPS56156280A JP S56156280 A JPS56156280 A JP S56156280A JP 5951180 A JP5951180 A JP 5951180A JP 5951180 A JP5951180 A JP 5951180A JP S56156280 A JPS56156280 A JP S56156280A
Authority
JP
Japan
Prior art keywords
formula
compound
preparation
theobromine
give
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5951180A
Other languages
Japanese (ja)
Inventor
Toshiyuki Takashima
Sei Kondo
Eiko Taima
Naoto Hatanaka
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nissan Chemical Corp
Sagami Chemical Research Institute
Original Assignee
Nissan Chemical Corp
Sagami Chemical Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nissan Chemical Corp, Sagami Chemical Research Institute filed Critical Nissan Chemical Corp
Priority to JP5951180A priority Critical patent/JPS56156280A/en
Publication of JPS56156280A publication Critical patent/JPS56156280A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:Compounds of formula I [R is group of formula II (R1 is lower alkyl, aryl)].
EXAMPLE: 1-(5'-Ethylthio-5'-hexenyl)-3,7-dimethylxanthine.
USE: A precursor of pentoxyfylline.
PREPARATION: The reaction of a compound of formula III such as methyl 1-methylthioethylsulfoxide with another compound of formula IV (X and X' are halogen) such as 1,4-dibromobutane is conducted in the presence of a base such as lithium diisopropylamide in a solvent such as diethyl ether at -78W150°C to give a compound of formula V. The product is made to react with theobromine in the presence of a base such as sodium hydroxide in a solvent such as diethyl ether at -78W 150°C to give the compound of formula I.
COPYRIGHT: (C)1981,JPO&Japio
JP5951180A 1980-05-07 1980-05-07 Theobromine derivative and its preparation Pending JPS56156280A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP5951180A JPS56156280A (en) 1980-05-07 1980-05-07 Theobromine derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5951180A JPS56156280A (en) 1980-05-07 1980-05-07 Theobromine derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS56156280A true JPS56156280A (en) 1981-12-02

Family

ID=13115349

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5951180A Pending JPS56156280A (en) 1980-05-07 1980-05-07 Theobromine derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS56156280A (en)

Similar Documents

Publication Publication Date Title
JPS5432460A (en) Cycloalkylidenemethylphenylacetic acid derivative and their preparation
JPS5795964A (en) Preparation of 2-substituted-3(2h)-pyridazinone derivative
JPS57116074A (en) Novel camptothecin derivative and its preparation
JPS57176982A (en) Dioxolanylazetidinone compound, its preparation and use
JPS56156280A (en) Theobromine derivative and its preparation
JPS5711981A (en) Theobromine derivative and its preparation
JPS5731671A (en) Preparation of homopiperazine derivative
JPS5762278A (en) Theobromine derivative and its preparation
JPS5798284A (en) Preparation of 1-(5-oxohexyl)-3,7-dimethylxanthine
JPS56127378A (en) 2-alkoxyindolizine derivative and its preparation
JPS56156263A (en) Carbostyril derivative
JPS5639074A (en) Pyrimidine derivative
JPS5742643A (en) 6,10,14,18-tetramethyl-5,9,13,17-nonadecatetraene-2-ol
JPS5566560A (en) Quinolone derivative
JPS55143984A (en) Novel xanthine derivative
JPS5714585A (en) 1-cycloalkylmethylpiperazine derivative
JPS55115868A (en) Beta,beta,beta-trihalo-alpha-hydroxyethyl substituted-2-aroyl pyrrole derivative
JPS5758890A (en) Preparation of glucosylmoranoline derivative
JPS5285175A (en) Amino-substituted propiophenone derivatives and medicaments containing same
JPS5625166A (en) 5-fluorouracil derivative
JPS5262280A (en) Preparation of novel butyrophenone derivatives
JPS56120669A (en) Allophanoylpiperazine compound and analgesic agent containing the same as active constituent
JPS5495580A (en) Isocarbostyril derivative
JPS5668673A (en) Substituted methylidenehydrazinopyrimidine derivative and its preparation
JPS568385A (en) 2-allyl-imidazo 1,2-a imidazole derivative