GB1032362A - Chromone derivatives - Google Patents

Chromone derivatives

Info

Publication number
GB1032362A
GB1032362A GB1222162A GB1222162A GB1032362A GB 1032362 A GB1032362 A GB 1032362A GB 1222162 A GB1222162 A GB 1222162A GB 1222162 A GB1222162 A GB 1222162A GB 1032362 A GB1032362 A GB 1032362A
Authority
GB
United Kingdom
Prior art keywords
hydrogen
sodium
chromone derivatives
cyclizing
hydrolysed
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1222162A
Inventor
Colin Fitzmaurice
Arthur Hedley Wragg
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BENGER LAB Ltd
Original Assignee
BENGER LAB Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BENGER LAB Ltd filed Critical BENGER LAB Ltd
Priority to GB1222162A priority Critical patent/GB1032362A/en
Publication of GB1032362A publication Critical patent/GB1032362A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/24—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

New compounds of formula <FORM:1032362/C2/1> and salts and esters thereof, where R2 and R3 are hydrogen or alkoxy (except both hydrogen or both methoxy) are prepared by condensing a 2-OH-3-R2-6-R3-acetophenone with diethyl oxalate in the presence of sodium hydride or sodium and cyclizing the intermediate either by heating to form the ethyl ester which is then hydrolysed or by reacting with acetic and hydrochloric acids to form the free acid. Pharmaceutical compositions comprise compounds I with carriers or diluents. Oral, parenteral and topical (including aerosol) preparations inhibiting antigen-antibody reactions are mentioned.
GB1222162A 1962-03-30 1962-03-30 Chromone derivatives Expired GB1032362A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1222162A GB1032362A (en) 1962-03-30 1962-03-30 Chromone derivatives

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1222162A GB1032362A (en) 1962-03-30 1962-03-30 Chromone derivatives

Publications (1)

Publication Number Publication Date
GB1032362A true GB1032362A (en) 1966-06-08

Family

ID=10000582

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1222162A Expired GB1032362A (en) 1962-03-30 1962-03-30 Chromone derivatives

Country Status (1)

Country Link
GB (1) GB1032362A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4920177A (en) * 1972-06-21 1974-02-22
JPS4920179A (en) * 1972-06-24 1974-02-22

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4920177A (en) * 1972-06-21 1974-02-22
JPS4920179A (en) * 1972-06-24 1974-02-22

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