JPS5515476B1 - - Google Patents
Info
- Publication number
- JPS5515476B1 JPS5515476B1 JP7194A JP9471A JPS5515476B1 JP S5515476 B1 JPS5515476 B1 JP S5515476B1 JP 7194 A JP7194 A JP 7194A JP 9471 A JP9471 A JP 9471A JP S5515476 B1 JPS5515476 B1 JP S5515476B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/18—Aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH10370A CH527194A (de) | 1970-01-06 | 1970-01-06 | Verfahren zur Herstellung von Isochinolin-Derivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5515476B1 true JPS5515476B1 (nl) | 1980-04-23 |
Family
ID=4179328
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP7194A Pending JPS5515476B1 (nl) | 1970-01-06 | 1971-01-06 |
Country Status (19)
| Country | Link |
|---|---|
| JP (1) | JPS5515476B1 (nl) |
| AT (1) | AT303041B (nl) |
| BE (1) | BE761219A (nl) |
| CA (1) | CA999866A (nl) |
| CH (2) | CH538477A (nl) |
| DE (1) | DE2062001C2 (nl) |
| DK (1) | DK125021B (nl) |
| ES (1) | ES387016A1 (nl) |
| FI (1) | FI49503C (nl) |
| FR (1) | FR2081412B1 (nl) |
| GB (1) | GB1335261A (nl) |
| IE (1) | IE34859B1 (nl) |
| IL (1) | IL35916A (nl) |
| NL (1) | NL171444C (nl) |
| NO (1) | NO135315C (nl) |
| PH (1) | PH9682A (nl) |
| SE (3) | SE368401B (nl) |
| YU (1) | YU33660B (nl) |
| ZA (1) | ZA708590B (nl) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003513074A (ja) * | 1999-11-03 | 2003-04-08 | アルバニー モレキュラー リサーチ インコーポレーティッド | アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用 |
| JP2004501860A (ja) * | 1999-11-03 | 2004-01-22 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | ノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するための、４−フェニル置換テトラヒドロイソキノリン類およびその利用 |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4595688A (en) * | 1983-06-23 | 1986-06-17 | Mcneilab, Inc. | Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof |
| ZA844402B (en) * | 1983-06-23 | 1986-01-29 | Mcneil Pharmaceutical | Hexahydropyrrolo(2,1-a)isoquinoline derivatives |
| US4719216A (en) * | 1983-06-23 | 1988-01-12 | Mcneilab, Inc. | Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants |
| GB2271566A (en) * | 1992-10-14 | 1994-04-20 | Merck & Co Inc | HIV integrase inhibitors |
| US7163949B1 (en) * | 1999-11-03 | 2007-01-16 | Amr Technology, Inc. | 4-phenyl substituted tetrahydroisoquinolines and use thereof |
| EP1113007A1 (en) * | 1999-12-24 | 2001-07-04 | Pfizer Inc. | Tetrahydroisoquinoline compounds as estrogen agonists/antagonists |
| BR0112350A (pt) | 2000-07-11 | 2003-06-24 | Albany Molecular Res Inc | Composto, composição farmacêutica, e, método de tratar um animal afligido por um distúrbio neurológico ou psicológico |
| ZA200701232B (en) | 2004-07-15 | 2008-08-27 | Amr Technology Inc | Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin |
| DK1899334T3 (da) | 2005-06-17 | 2008-11-24 | Janssen Pharmaceutica Nv | Naphthyridinforbindelser |
| US7956050B2 (en) | 2005-07-15 | 2011-06-07 | Albany Molecular Research, Inc. | Aryl- and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| AR071997A1 (es) | 2008-06-04 | 2010-07-28 | Bristol Myers Squibb Co | Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina |
| US9156812B2 (en) | 2008-06-04 | 2015-10-13 | Bristol-Myers Squibb Company | Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine |
| JP5739415B2 (ja) | 2009-05-12 | 2015-06-24 | ブリストル−マイヤーズ スクウィブ カンパニー | （Ｓ）−７−（［１，２，４］トリアゾロ［１，５−ａ］ピリジン−６−イル）−４−（３，４−ジクロロフェニル）−１，２，３，４−テトラヒドロイソキノリンの結晶形態およびその使用 |
| WO2010132437A1 (en) | 2009-05-12 | 2010-11-18 | Albany Molecular Research, Inc. | Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof |
| CA2760837C (en) | 2009-05-12 | 2018-04-03 | Albany Molecular Research, Inc. | 7-([1,2,4]triazolo[1,5-.alpha.]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE1670694B2 (de) * | 1966-05-05 | 1976-07-22 | Hoechst Ag, 6000 Frankfurt | Verfahren zur herstellung von tetrahydroisochinolinen |
-
1970
- 1970-01-06 CH CH1011872A patent/CH538477A/de not_active IP Right Cessation
- 1970-01-06 CH CH10370A patent/CH527194A/de not_active IP Right Cessation
- 1970-12-16 SE SE17063/70A patent/SE368401B/xx unknown
- 1970-12-16 DE DE2062001A patent/DE2062001C2/de not_active Expired
- 1970-12-16 SE SE7313623A patent/SE386672B/xx unknown
- 1970-12-21 ZA ZA708590A patent/ZA708590B/xx unknown
- 1970-12-28 IL IL35916A patent/IL35916A/xx unknown
- 1970-12-29 NL NLAANVRAGE7018956,A patent/NL171444C/nl not_active IP Right Cessation
- 1970-12-31 FI FI703519A patent/FI49503C/fi active
-
1971
- 1971-01-04 IE IE6/71A patent/IE34859B1/xx unknown
- 1971-01-05 DK DK2571AA patent/DK125021B/da not_active IP Right Cessation
- 1971-01-05 BE BE761219A patent/BE761219A/xx not_active IP Right Cessation
- 1971-01-05 NO NO7121A patent/NO135315C/no unknown
- 1971-01-05 ES ES387016A patent/ES387016A1/es not_active Expired
- 1971-01-05 AT AT4571A patent/AT303041B/de not_active IP Right Cessation
- 1971-01-05 GB GB45471A patent/GB1335261A/en not_active Expired
- 1971-01-05 FR FR7100097A patent/FR2081412B1/fr not_active Expired
- 1971-01-06 CA CA102,060A patent/CA999866A/en not_active Expired
- 1971-01-06 YU YU19/71A patent/YU33660B/xx unknown
- 1971-01-06 JP JP7194A patent/JPS5515476B1/ja active Pending
- 1971-01-07 PH PH12087*UA patent/PH9682A/en unknown
-
1973
- 1973-10-05 SE SE7313622A patent/SE399879B/xx unknown
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003513074A (ja) * | 1999-11-03 | 2003-04-08 | アルバニー モレキュラー リサーチ インコーポレーティッド | アリールおよびヘテロアリール置換テトラヒドロイソキノリン、ならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを阻止するためのそれらの使用 |
| JP2004501860A (ja) * | 1999-11-03 | 2004-01-22 | ブリストル−マイヤーズ・スクイブ・ファーマ・カンパニー | ノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するための、４−フェニル置換テトラヒドロイソキノリン類およびその利用 |
Also Published As
| Publication number | Publication date |
|---|---|
| FI49503C (fi) | 1975-07-10 |
| CH538477A (de) | 1973-06-30 |
| IE34859L (en) | 1971-07-06 |
| CH527194A (de) | 1972-08-31 |
| DE2062001A1 (de) | 1971-07-15 |
| DE2062001C2 (de) | 1986-10-16 |
| IL35916A0 (en) | 1971-02-25 |
| NL7018956A (nl) | 1971-07-08 |
| ZA708590B (en) | 1971-09-29 |
| NO135315C (nl) | 1977-03-23 |
| FR2081412B1 (nl) | 1974-04-12 |
| CA999866A (en) | 1976-11-16 |
| SE386672B (sv) | 1976-08-16 |
| PH9682A (en) | 1976-02-10 |
| YU33660B (en) | 1977-12-31 |
| NO135315B (nl) | 1976-12-13 |
| FI49503B (nl) | 1975-04-01 |
| FR2081412A1 (nl) | 1971-12-03 |
| IE34859B1 (en) | 1975-09-03 |
| NL171444B (nl) | 1982-11-01 |
| SE399879B (sv) | 1978-03-06 |
| BE761219A (fr) | 1971-07-05 |
| NL171444C (nl) | 1983-04-05 |
| SE368401B (nl) | 1974-07-01 |
| AT303041B (de) | 1972-11-10 |
| GB1335261A (en) | 1973-10-24 |
| IL35916A (en) | 1973-11-28 |
| YU1971A (en) | 1977-06-30 |
| DK125021B (da) | 1972-12-18 |
| ES387016A1 (es) | 1976-05-01 |