JPS55129290A - Manufacture of cephalosporins - Google Patents

Manufacture of cephalosporins

Info

Publication number
JPS55129290A
JPS55129290A JP15129379A JP15129379A JPS55129290A JP S55129290 A JPS55129290 A JP S55129290A JP 15129379 A JP15129379 A JP 15129379A JP 15129379 A JP15129379 A JP 15129379A JP S55129290 A JPS55129290 A JP S55129290A
Authority
JP
Japan
Prior art keywords
cephalosporins
manufacture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP15129379A
Other languages
English (en)
Other versions
JPH0214358B2 (ja
Inventor
Uorukaa Dereku
Eichi Shirubuesutori Haabaato
Sapino Chiesutaa
Ei Jiyonson Deibuitsudo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of JPS55129290A publication Critical patent/JPS55129290A/ja
Publication of JPH0214358B2 publication Critical patent/JPH0214358B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06Acylation of 7-aminocephalosporanic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
JP15129379A 1979-03-19 1979-11-21 Manufacture of cephalosporins Granted JPS55129290A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/021,511 US4223135A (en) 1979-03-19 1979-03-19 Production of cephalosporins

Publications (2)

Publication Number Publication Date
JPS55129290A true JPS55129290A (en) 1980-10-06
JPH0214358B2 JPH0214358B2 (ja) 1990-04-06

Family

ID=21804643

Family Applications (2)

Application Number Title Priority Date Filing Date
JP15129379A Granted JPS55129290A (en) 1979-03-19 1979-11-21 Manufacture of cephalosporins
JP61278500A Granted JPS62161789A (ja) 1979-03-19 1986-11-21 セフアロスポリン類の製造法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP61278500A Granted JPS62161789A (ja) 1979-03-19 1986-11-21 セフアロスポリン類の製造法

Country Status (21)

Country Link
US (1) US4223135A (ja)
JP (2) JPS55129290A (ja)
AR (1) AR231143A1 (ja)
CA (1) CA1130278A (ja)
CH (1) CH642969A5 (ja)
DE (1) DE2951477A1 (ja)
DK (2) DK161522C (ja)
ES (2) ES486463A0 (ja)
FI (1) FI74709C (ja)
FR (1) FR2467213A1 (ja)
GB (1) GB2044248B (ja)
GR (1) GR82675B (ja)
HU (2) HU180687B (ja)
IE (1) IE49212B1 (ja)
IL (1) IL58396A (ja)
IT (1) IT1164907B (ja)
NL (1) NL7907551A (ja)
NO (1) NO158137C (ja)
PH (1) PH15449A (ja)
SE (2) SE445554B (ja)
ZA (1) ZA795132B (ja)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069482B (en) * 1980-02-14 1984-04-04 Gist Brocades Nv Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives
AT381315B (de) * 1984-11-23 1986-09-25 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate
EP1773845A1 (en) * 2004-07-16 2007-04-18 Hetero Drugs Limited Process for preparing pure cephalosporine intermediates
US7207857B2 (en) * 2005-09-20 2007-04-24 Patent Category Corp. Floating assemblies
BRPI0711924B1 (pt) * 2006-05-19 2023-11-28 Centrient Pharmaceuticals Netherlands B.V. Processo para a preparação de cefadroxil monoidratado em forma de cristal

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (ja) 1962-12-14 1969-06-16 Astra Ab
CH527215A (de) * 1967-04-15 1972-08-31 Fujisawa Pharmaceutical Co Verfahren zur Herstellung von 3,7-disubstituierten Cephalosporinderivaten
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
GB1332306A (en) * 1969-12-23 1973-10-03 Glaxo Lab Ltd Antibiotics
US3671449A (en) * 1970-08-19 1972-06-20 Lilly Co Eli Cephalosporin compositions
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3828037A (en) * 1972-07-20 1974-08-06 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US4051131A (en) * 1972-11-29 1977-09-27 American Home Products Corporation (Del.) Intermediates for preparing cephalosporins
US3965098A (en) * 1972-11-29 1976-06-22 American Home Products Corporation Intermediates for preparing cephalosporins and methods of production
US3928336A (en) * 1974-07-29 1975-12-23 Bristol Myers Co 7-{8 D-({60 -amino{60 -phenyl-, 2-thienyl- and 3-thienyl-acetamido){9 -3-(3-methyl-1,2,5-oxadiazol-4-yl)carbonylthiomethyl-3-cephem-4-carboxylic acids
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent

Also Published As

Publication number Publication date
DK406579A (da) 1981-03-28
JPH0351715B2 (ja) 1991-08-07
SE7907902L (sv) 1980-09-20
CA1130278A (en) 1982-08-24
IL58396A (en) 1983-06-15
FR2467213A1 (fr) 1981-04-17
JPS62161789A (ja) 1987-07-17
ES8102577A1 (es) 1981-01-16
DK164365C (da) 1992-11-16
IT7950520A0 (it) 1979-10-10
IE49212B1 (en) 1985-08-21
SE458608B (sv) 1989-04-17
SE445554B (sv) 1986-06-30
NL7907551A (nl) 1980-09-23
DK8891A (da) 1991-01-18
CH642969A5 (de) 1984-05-15
FI74709B (fi) 1987-11-30
FI792995A (fi) 1980-09-20
HU188767B (en) 1986-05-28
NO158137B (no) 1988-04-11
ES8105327A1 (es) 1981-06-01
IL58396A0 (en) 1980-01-31
DK164365B (da) 1992-06-15
US4223135A (en) 1980-09-16
ZA795132B (en) 1981-06-24
DK161522B (da) 1991-07-15
DE2951477C2 (ja) 1987-07-23
JPH0214358B2 (ja) 1990-04-06
AR231143A1 (es) 1984-09-28
GR82675B (ja) 1985-02-07
GB2044248A (en) 1980-10-15
IE792211L (en) 1980-09-19
DE2951477A1 (de) 1980-10-09
FR2467213B1 (ja) 1984-01-06
NO793103L (no) 1980-09-22
NO158137C (no) 1988-07-20
IT1164907B (it) 1987-04-15
SE8404730L (sv) 1984-09-20
ES492956A0 (es) 1981-06-01
SE8404730D0 (sv) 1984-09-20
FI74709C (fi) 1988-03-10
DK161522C (da) 1991-12-23
DK8891D0 (da) 1991-01-18
HU180687B (en) 1983-04-29
GB2044248B (en) 1983-04-20
PH15449A (en) 1983-01-18
ES486463A0 (es) 1981-01-16

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