IT1164907B - Procedimento per la produzione di cefalosporine - Google Patents

Procedimento per la produzione di cefalosporine

Info

Publication number
IT1164907B
IT1164907B IT50520/79A IT5052079A IT1164907B IT 1164907 B IT1164907 B IT 1164907B IT 50520/79 A IT50520/79 A IT 50520/79A IT 5052079 A IT5052079 A IT 5052079A IT 1164907 B IT1164907 B IT 1164907B
Authority
IT
Italy
Prior art keywords
cephalosporins
procedure
production
Prior art date
Application number
IT50520/79A
Other languages
English (en)
Other versions
IT7950520A0 (it
Inventor
Derek Walker
Herbert H Silvestri
Chester Sapino
David A Johnson
Original Assignee
Bristol Myers Co Societa Dello
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co Societa Dello filed Critical Bristol Myers Co Societa Dello
Publication of IT7950520A0 publication Critical patent/IT7950520A0/it
Application granted granted Critical
Publication of IT1164907B publication Critical patent/IT1164907B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02Preparation
    • C07D501/04Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C07D501/06Acylation of 7-aminocephalosporanic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/10Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)
IT50520/79A 1979-03-19 1979-10-10 Procedimento per la produzione di cefalosporine IT1164907B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/021,511 US4223135A (en) 1979-03-19 1979-03-19 Production of cephalosporins

Publications (2)

Publication Number Publication Date
IT7950520A0 IT7950520A0 (it) 1979-10-10
IT1164907B true IT1164907B (it) 1987-04-15

Family

ID=21804643

Family Applications (1)

Application Number Title Priority Date Filing Date
IT50520/79A IT1164907B (it) 1979-03-19 1979-10-10 Procedimento per la produzione di cefalosporine

Country Status (21)

Country Link
US (1) US4223135A (it)
JP (2) JPS55129290A (it)
AR (1) AR231143A1 (it)
CA (1) CA1130278A (it)
CH (1) CH642969A5 (it)
DE (1) DE2951477A1 (it)
DK (2) DK161522C (it)
ES (2) ES486463A0 (it)
FI (1) FI74709C (it)
FR (1) FR2467213A1 (it)
GB (1) GB2044248B (it)
GR (1) GR82675B (it)
HU (2) HU180687B (it)
IE (1) IE49212B1 (it)
IL (1) IL58396A (it)
IT (1) IT1164907B (it)
NL (1) NL7907551A (it)
NO (1) NO158137C (it)
PH (1) PH15449A (it)
SE (2) SE445554B (it)
ZA (1) ZA795132B (it)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2069482B (en) * 1980-02-14 1984-04-04 Gist Brocades Nv Process for the preparation of 3'-bromosubstituted deacetoxycephalosporanic acid sulphoxide derivatives
AT381315B (de) * 1984-11-23 1986-09-25 Biochemie Gmbh Verfahren zur herstellung von cephalosporinderivaten
US4868294A (en) * 1986-07-11 1989-09-19 Bristol-Myers Company Process for preparing cephalosporin intermediates
US5142043A (en) * 1990-05-10 1992-08-25 Biocraft Laboratories, Inc. Process for preparing cephalexin monohydrate
WO2006008749A1 (en) * 2004-07-16 2006-01-26 Hetero Drugs Limited Process for preparing pure cephalosporine intermediates
US7207857B2 (en) * 2005-09-20 2007-04-24 Patent Category Corp. Floating assemblies
CN101448842A (zh) * 2006-05-19 2009-06-03 帝斯曼知识产权资产管理有限公司 一种用于结晶头孢羟氨苄的方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE311519B (it) 1962-12-14 1969-06-16 Astra Ab
CH557381A (de) * 1967-04-15 1974-12-31 Fujisawa Pharmaceutical Co Verfahren zur herstellung von (delta)3-cephemverbindungen.
US3819623A (en) * 1968-04-12 1974-06-25 Fujisawa Pharmaceutical Co 3,7-disubstituted cephalosporin compounds
US3641021A (en) * 1969-04-18 1972-02-08 Lilly Co Eli 3 7-(ring-substituted) cephalosporin compounds
GB1332306A (en) * 1969-12-23 1973-10-03 Glaxo Lab Ltd Antibiotics
US3694437A (en) * 1970-08-19 1972-09-26 Lilly Co Eli Process for preparing cephalosporin compounds
US3671449A (en) * 1970-08-19 1972-06-20 Lilly Co Eli Cephalosporin compositions
US3867380A (en) * 1971-02-18 1975-02-18 Smithkline Corp 3-Heterocyclic thiomethylcephalosporins
US3828037A (en) * 1972-07-20 1974-08-06 Smithkline Corp Trifluoromethylmercaptoacetamidocephalosporins
US4051131A (en) * 1972-11-29 1977-09-27 American Home Products Corporation (Del.) Intermediates for preparing cephalosporins
US3965098A (en) * 1972-11-29 1976-06-22 American Home Products Corporation Intermediates for preparing cephalosporins and methods of production
US3928336A (en) * 1974-07-29 1975-12-23 Bristol Myers Co 7-{8 D-({60 -amino{60 -phenyl-, 2-thienyl- and 3-thienyl-acetamido){9 -3-(3-methyl-1,2,5-oxadiazol-4-yl)carbonylthiomethyl-3-cephem-4-carboxylic acids
JPS525787A (en) * 1975-06-27 1977-01-17 Bristol Myers Co Antiibacterial agent

Also Published As

Publication number Publication date
NO793103L (no) 1980-09-22
NL7907551A (nl) 1980-09-23
SE445554B (sv) 1986-06-30
IL58396A0 (en) 1980-01-31
ES492956A0 (es) 1981-06-01
DE2951477C2 (it) 1987-07-23
GB2044248A (en) 1980-10-15
SE7907902L (sv) 1980-09-20
PH15449A (en) 1983-01-18
ZA795132B (en) 1981-06-24
DK164365B (da) 1992-06-15
FR2467213B1 (it) 1984-01-06
CH642969A5 (de) 1984-05-15
GB2044248B (en) 1983-04-20
ES8102577A1 (es) 1981-01-16
NO158137B (no) 1988-04-11
IE49212B1 (en) 1985-08-21
IE792211L (en) 1980-09-19
GR82675B (it) 1985-02-07
DK406579A (da) 1981-03-28
IT7950520A0 (it) 1979-10-10
US4223135A (en) 1980-09-16
FR2467213A1 (fr) 1981-04-17
DK8891A (da) 1991-01-18
HU188767B (en) 1986-05-28
FI74709B (fi) 1987-11-30
CA1130278A (en) 1982-08-24
DK161522B (da) 1991-07-15
DK8891D0 (da) 1991-01-18
DK161522C (da) 1991-12-23
SE458608B (sv) 1989-04-17
SE8404730L (sv) 1984-09-20
AR231143A1 (es) 1984-09-28
FI792995A (fi) 1980-09-20
DE2951477A1 (de) 1980-10-09
NO158137C (no) 1988-07-20
JPS55129290A (en) 1980-10-06
FI74709C (fi) 1988-03-10
IL58396A (en) 1983-06-15
JPS62161789A (ja) 1987-07-17
ES8105327A1 (es) 1981-06-01
SE8404730D0 (sv) 1984-09-20
ES486463A0 (es) 1981-01-16
JPH0351715B2 (it) 1991-08-07
HU180687B (en) 1983-04-29
DK164365C (da) 1992-11-16
JPH0214358B2 (it) 1990-04-06

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