JPS55104296A - Antibiotic substance c-19393s2 and its preparation - Google Patents
Antibiotic substance c-19393s2 and its preparationInfo
- Publication number
- JPS55104296A JPS55104296A JP1156079A JP1156079A JPS55104296A JP S55104296 A JPS55104296 A JP S55104296A JP 1156079 A JP1156079 A JP 1156079A JP 1156079 A JP1156079 A JP 1156079A JP S55104296 A JPS55104296 A JP S55104296A
- Authority
- JP
- Japan
- Prior art keywords
- gram
- positive
- supernatant liquid
- cultivation product
- soluble
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000126 substance Substances 0.000 title abstract 3
- 230000003115 biocidal effect Effects 0.000 title abstract 2
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 abstract 3
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 abstract 3
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- 238000006243 chemical reaction Methods 0.000 abstract 3
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 abstract 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 2
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 abstract 2
- 239000007788 liquid Substances 0.000 abstract 2
- 239000000047 product Substances 0.000 abstract 2
- 239000006228 supernatant Substances 0.000 abstract 2
- 241000894006 Bacteria Species 0.000 abstract 1
- 229930186147 Cephalosporin Natural products 0.000 abstract 1
- 208000035473 Communicable disease Diseases 0.000 abstract 1
- 229930182555 Penicillin Natural products 0.000 abstract 1
- JGSARLDLIJGVTE-MBNYWOFBSA-N Penicillin G Chemical compound N([C@H]1[C@H]2SC([C@@H](N2C1=O)C(O)=O)(C)C)C(=O)CC1=CC=CC=C1 JGSARLDLIJGVTE-MBNYWOFBSA-N 0.000 abstract 1
- 241000187180 Streptomyces sp. Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 239000004599 antimicrobial Substances 0.000 abstract 1
- 230000001580 bacterial effect Effects 0.000 abstract 1
- 229940124587 cephalosporin Drugs 0.000 abstract 1
- 150000001780 cephalosporins Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 abstract 1
- 229940049954 penicillin Drugs 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 abstract 1
- 238000000926 separation method Methods 0.000 abstract 1
- 230000002195 synergetic effect Effects 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
- C07D477/20—Sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/182—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system
- C12P17/184—Heterocyclic compounds containing nitrogen atoms as the only ring heteroatoms in the condensed system containing a beta-lactam ring, e.g. thienamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Compounds Of Unknown Constitution (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (19)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1156079A JPS55104296A (en) | 1979-02-02 | 1979-02-02 | Antibiotic substance c-19393s2 and its preparation |
| AU54518/80A AU534530B2 (en) | 1979-02-02 | 1980-01-10 | 5-aza-(3.2.0)-heptane derivatives |
| DK12580A DK12580A (da) | 1979-02-02 | 1980-01-11 | Antibiotika c-19393s2 og h2 |
| GR60953A GR73818B (enrdf_load_stackoverflow) | 1979-02-02 | 1980-01-14 | |
| US06/113,132 US4518529A (en) | 1979-02-02 | 1980-01-17 | Antibiotics C-19393S2 |
| PT70710A PT70710A (en) | 1979-02-02 | 1980-01-18 | Antibiotics c-19393 s2 and h2 |
| HU80180A HU181721B (en) | 1979-02-02 | 1980-01-28 | Process for preparing antibiotics c-19393sdown 2 and c-1939hdown 2 |
| ZA00800496A ZA80496B (en) | 1979-02-02 | 1980-01-28 | Antibiotics c-19393s2 and h2 |
| CH67680A CH646432A5 (de) | 1979-02-02 | 1980-01-28 | Beta-lactam-antibiotika. |
| NL8000628A NL8000628A (nl) | 1979-02-02 | 1980-01-31 | Antibiotica c-19393s2 en h2. |
| FR8002162A FR2447922A1 (fr) | 1979-02-02 | 1980-01-31 | Antibiotiques c-19393 s2 et c-19393 h2 et leurs sels, leur procede de preparation a partir de micro-organismes du genre streptomyces et leur utilisation dans des preparations medicinales |
| ES488836A ES8102590A1 (es) | 1979-02-02 | 1980-01-31 | Metodo de producir antibioticos del tipo basado en streptomyces. |
| SE8000842A SE8000842L (sv) | 1979-02-02 | 1980-02-01 | Nya antibiotika |
| BE0/199232A BE881509A (fr) | 1979-02-02 | 1980-02-01 | Antibiotiques c-19393 s2 et c-19393 h2 et leurs sels, leur procede de preparation a partir de micro-organismes et leur utilisation |
| IT19645/80A IT1130246B (it) | 1979-02-02 | 1980-02-01 | Antibiotico e procedimento microbiologico per produrlo |
| GB8003402A GB2042532B (en) | 1979-02-02 | 1980-02-01 | Antibiotics c-19393 s2 and 'i |
| DE19803003624 DE3003624A1 (de) | 1979-02-02 | 1980-02-01 | Antibiotica c-19393 s tief 2 und h tief 2 |
| SU802878699A SU1075984A3 (ru) | 1979-02-02 | 1980-02-01 | Способ получени антибиотика @ -19393 @ и/или @ -19393 @ |
| PH23567A PH14316A (en) | 1979-02-02 | 1980-02-01 | Antibiotics c-19393 s2 and h2 and method of preparation thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP1156079A JPS55104296A (en) | 1979-02-02 | 1979-02-02 | Antibiotic substance c-19393s2 and its preparation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS55104296A true JPS55104296A (en) | 1980-08-09 |
| JPS6125356B2 JPS6125356B2 (enrdf_load_stackoverflow) | 1986-06-14 |
Family
ID=11781312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1156079A Granted JPS55104296A (en) | 1979-02-02 | 1979-02-02 | Antibiotic substance c-19393s2 and its preparation |
Country Status (3)
| Country | Link |
|---|---|
| JP (1) | JPS55104296A (enrdf_load_stackoverflow) |
| BE (1) | BE881509A (enrdf_load_stackoverflow) |
| ZA (1) | ZA80496B (enrdf_load_stackoverflow) |
-
1979
- 1979-02-02 JP JP1156079A patent/JPS55104296A/ja active Granted
-
1980
- 1980-01-28 ZA ZA00800496A patent/ZA80496B/xx unknown
- 1980-02-01 BE BE0/199232A patent/BE881509A/fr not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6125356B2 (enrdf_load_stackoverflow) | 1986-06-14 |
| ZA80496B (en) | 1981-02-25 |
| BE881509A (fr) | 1980-08-01 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JPS5549394A (en) | Antibiotic substance sb-72310 | |
| JPS54163501A (en) | Antibiotic substance g-6302 | |
| JPS5661398A (en) | Substance dc-45 and its preparation | |
| JPS55104296A (en) | Antibiotic substance c-19393s2 and its preparation | |
| JPS568688A (en) | Antitumor substance 1166a and its preparation | |
| JPS568687A (en) | Preparation of creatinase | |
| IE37892B1 (en) | Antibiotic a-2315 and process for preparation thereof | |
| JPS5788195A (en) | Antibiotic, oxanosine, and its preparation | |
| JPS54154792A (en) | Novel antibiotic a-11079-b1b and its preparation | |
| JPS57154195A (en) | Novel antibiotic lysopeptin a and b and their preparations | |
| JPS57109798A (en) | Antibiotic substance and its preparation | |
| JPS56142250A (en) | Antibiotic, mycoplanecin c, and its preparation | |
| JPS55124794A (en) | Cytophagin and its preparation | |
| SU440847A1 (ru) | Способ получения антибиотика | |
| JPS5699495A (en) | Novel antibiotic substance, its preparation, and pharmaceutical containing said substance as effective component | |
| IE42705L (en) | Cephalosporin compounds. | |
| JPS5782397A (en) | Novel antibiotic 5057b substance and its preparation | |
| JPS5785397A (en) | Novel antibiotic sf-2140 substance and its preparation | |
| JPS5643295A (en) | Istamycin ao and/or istamycin bo, and their preparation | |
| JPS54126793A (en) | Novel antibiotic no.49a substance and its preparation | |
| JPS5770890A (en) | Novel antibiotic oa-6129b and its preparation | |
| JPS5579396A (en) | Novel antibiotic, sf-2012-l substance, and its preparation | |
| JPS5791993A (en) | Novel antibiotic substance, its preparation and microorganism capable of producing the same | |
| IE37401L (en) | Acne preparation for oral administration. | |
| JPS55100395A (en) | Novel substance tpj-b and its preparation |