IE42705L - Cephalosporin compounds. - Google Patents
Cephalosporin compounds.Info
- Publication number
- IE42705L IE42705L IE750705A IE70575A IE42705L IE 42705 L IE42705 L IE 42705L IE 750705 A IE750705 A IE 750705A IE 70575 A IE70575 A IE 70575A IE 42705 L IE42705 L IE 42705L
- Authority
- IE
- Ireland
- Prior art keywords
- formula
- compounds
- compound
- cephalosporin compounds
- gb1504589a
- Prior art date
Links
- 229930186147 Cephalosporin Natural products 0.000 title abstract 2
- -1 Cephalosporin compounds Chemical class 0.000 title abstract 2
- 229940124587 cephalosporin Drugs 0.000 title abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 4
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
- C07C273/1863—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety from urea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C273/00—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C273/18—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas
- C07C273/1854—Preparation of urea or its derivatives, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups of substituted ureas by reactions not involving the formation of the N-C(O)-N- moiety
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
A process is described for the preparation of novel cephalosporin compounds of the formula I, which are substituted by a ureido radical, by reaction of a compound of the formula II with a compound of the formula (III) R''-NH-CO-N(R')-CO-A. These can be converted into the esters of the formula IV which are likewise new. The substituents in the compounds of the formula I and IV have the meanings stated in Claim 1 and Claim 10 respectively. The compounds of the formula I and IV have a high activity and a broad spectrum of action as antibiotics and are particularly suitable for the treatment of infections caused by Gram-negative microorganisms. <IMAGE>
[GB1504589A]
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US45651674A | 1974-04-01 | 1974-04-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE42705L true IE42705L (en) | 1975-10-01 |
| IE42705B1 IE42705B1 (en) | 1980-10-08 |
Family
ID=23813076
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE705/75A IE42705B1 (en) | 1974-04-01 | 1975-04-02 | Substituted cephalosporin antibiotics |
Country Status (23)
| Country | Link |
|---|---|
| JP (1) | JPS614837B2 (en) |
| AR (1) | AR210258A1 (en) |
| AT (1) | AT337896B (en) |
| BE (1) | BE827408A (en) |
| BG (1) | BG27376A3 (en) |
| CA (1) | CA1096373A (en) |
| CH (1) | CH627471A5 (en) |
| CS (1) | CS196261B2 (en) |
| DD (1) | DD118648A5 (en) |
| DE (1) | DE2514019A1 (en) |
| DK (1) | DK130375A (en) |
| ES (1) | ES436198A1 (en) |
| FR (1) | FR2265394B1 (en) |
| GB (1) | GB1504589A (en) |
| HU (1) | HU170816B (en) |
| IE (1) | IE42705B1 (en) |
| IL (1) | IL46956A (en) |
| NL (1) | NL7503883A (en) |
| PH (1) | PH13642A (en) |
| PL (1) | PL101400B1 (en) |
| RO (1) | RO67392A (en) |
| SE (1) | SE423392B (en) |
| ZA (1) | ZA752004B (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4063019A (en) | 1976-03-30 | 1977-12-13 | E. R. Squibb & Sons, Inc. | [[[(2,4-Dioxo-1-imidazolidinyl)amino]carbonyl]amino]-acetylcephalosporin derivatives |
| CN1069639C (en) * | 1998-06-19 | 2001-08-15 | 山东沂蒙新华制药厂 | Preparation process of 1-chloroformyl-3-mesyl imidazolyl alkyl ketone |
-
1975
- 1975-03-26 DK DK130375A patent/DK130375A/da not_active Application Discontinuation
- 1975-03-28 IL IL46956A patent/IL46956A/en unknown
- 1975-03-28 HU HU75EI00000607A patent/HU170816B/en unknown
- 1975-03-29 PL PL1975179227A patent/PL101400B1/en unknown
- 1975-03-29 BG BG029484A patent/BG27376A3/en unknown
- 1975-03-29 DE DE19752514019 patent/DE2514019A1/en not_active Ceased
- 1975-03-31 PH PH16988A patent/PH13642A/en unknown
- 1975-03-31 RO RO7581853A patent/RO67392A/en unknown
- 1975-04-01 NL NL7503883A patent/NL7503883A/en not_active Application Discontinuation
- 1975-04-01 GB GB13383/75A patent/GB1504589A/en not_active Expired
- 1975-04-01 CH CH411575A patent/CH627471A5/en not_active IP Right Cessation
- 1975-04-01 JP JP50040203A patent/JPS614837B2/ja not_active Expired
- 1975-04-01 FR FR7510143A patent/FR2265394B1/fr not_active Expired
- 1975-04-01 SE SE7503707-7A patent/SE423392B/en unknown
- 1975-04-01 BE BE1006559A patent/BE827408A/en not_active IP Right Cessation
- 1975-04-01 DD DD185120A patent/DD118648A5/xx unknown
- 1975-04-01 ZA ZA752004A patent/ZA752004B/en unknown
- 1975-04-01 AT AT247675A patent/AT337896B/en not_active IP Right Cessation
- 1975-04-01 CS CS752206A patent/CS196261B2/en unknown
- 1975-04-01 CA CA223,530A patent/CA1096373A/en not_active Expired
- 1975-04-01 ES ES436198A patent/ES436198A1/en not_active Expired
- 1975-04-02 IE IE705/75A patent/IE42705B1/en unknown
- 1975-04-10 AR AR258200A patent/AR210258A1/en active
Also Published As
| Publication number | Publication date |
|---|---|
| AU7963775A (en) | 1976-09-30 |
| IE42705B1 (en) | 1980-10-08 |
| IL46956A0 (en) | 1975-05-22 |
| ES436198A1 (en) | 1977-01-01 |
| DE2514019A1 (en) | 1975-10-02 |
| SE7503707L (en) | 1975-10-02 |
| FR2265394B1 (en) | 1978-07-28 |
| HU170816B (en) | 1977-09-28 |
| CA1096373A (en) | 1981-02-24 |
| BE827408A (en) | 1975-10-01 |
| CH627471A5 (en) | 1982-01-15 |
| AR210258A1 (en) | 1977-07-15 |
| DD118648A5 (en) | 1976-03-12 |
| GB1504589A (en) | 1978-03-22 |
| NL7503883A (en) | 1975-10-03 |
| IL46956A (en) | 1979-10-31 |
| JPS614837B2 (en) | 1986-02-13 |
| SE423392B (en) | 1985-05-03 |
| ZA752004B (en) | 1976-11-24 |
| CS196261B2 (en) | 1980-03-31 |
| BG27376A3 (en) | 1979-10-12 |
| PH13642A (en) | 1980-08-18 |
| DK130375A (en) | 1975-10-02 |
| PL101400B1 (en) | 1978-12-30 |
| JPS50137995A (en) | 1975-11-01 |
| FR2265394A1 (en) | 1975-10-24 |
| AT337896B (en) | 1977-07-25 |
| ATA247675A (en) | 1976-11-15 |
| RO67392A (en) | 1981-04-30 |
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