JPS54154786A - Cephalosporin compound - Google Patents

Cephalosporin compound

Info

Publication number
JPS54154786A
JPS54154786A JP6669579A JP6669579A JPS54154786A JP S54154786 A JPS54154786 A JP S54154786A JP 6669579 A JP6669579 A JP 6669579A JP 6669579 A JP6669579 A JP 6669579A JP S54154786 A JPS54154786 A JP S54154786A
Authority
JP
Japan
Prior art keywords
cephalosporin compound
cephalosporin
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP6669579A
Other languages
English (en)
Japanese (ja)
Other versions
JPS625916B2 (de
Inventor
Hiruda Okiyarahan Shinshia
Jiyooji Hiyuubaato Deibitsudo
Aaru Niyuuooru Kurisutofuaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of JPS54154786A publication Critical patent/JPS54154786A/ja
Publication of JPS625916B2 publication Critical patent/JPS625916B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
    • C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP6669579A 1978-05-26 1979-05-25 Cephalosporin compound Granted JPS54154786A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB2291178 1978-05-26

Publications (2)

Publication Number Publication Date
JPS54154786A true JPS54154786A (en) 1979-12-06
JPS625916B2 JPS625916B2 (de) 1987-02-07

Family

ID=10187065

Family Applications (6)

Application Number Title Priority Date Filing Date
JP6669579A Granted JPS54154786A (en) 1978-05-26 1979-05-25 Cephalosporin compound
JP3813280A Pending JPS55149289A (en) 1978-05-26 1980-03-24 Cephalosporin compound
JP6315985A Granted JPS6127990A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物
JP6315885A Granted JPS6127989A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物の製法
JP6315785A Granted JPS6127921A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物を有効成分とする薬学的組成物
JP62142418A Granted JPS6322093A (ja) 1978-05-26 1987-06-09 セフアロスポリン化合物の製法

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP3813280A Pending JPS55149289A (en) 1978-05-26 1980-03-24 Cephalosporin compound
JP6315985A Granted JPS6127990A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物
JP6315885A Granted JPS6127989A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物の製法
JP6315785A Granted JPS6127921A (ja) 1978-05-26 1985-03-27 セフアロスポリン化合物を有効成分とする薬学的組成物
JP62142418A Granted JPS6322093A (ja) 1978-05-26 1987-06-09 セフアロスポリン化合物の製法

Country Status (10)

Country Link
JP (6) JPS54154786A (de)
KR (2) KR830000606B1 (de)
AT (2) AT369381B (de)
BE (1) BE876538A (de)
CA (1) CA1132538A (de)
CY (1) CY1168A (de)
GB (2) GB2025398B (de)
HU (1) HU184631B (de)
IT (1) IT1210588B (de)
ZA (2) ZA807323B (de)

Cited By (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5756486A (en) * 1980-08-11 1982-04-05 Fujisawa Pharmaceut Co Ltd Novel cephem compound or its salt, their preparation and prophylactic or remedy for microbism containing the same as active ingredient
JPS58162592A (ja) * 1982-03-04 1983-09-27 ヘキスト　アクチェンゲゼルシャフト セフアロスポリン誘導体およびその製造方法
JPS5993086A (ja) * 1982-10-23 1984-05-29 バイエル・アクチエンゲゼルシヤフト セフアロスポリン類およびそれらの製造法
JPS59130889A (ja) * 1982-12-27 1984-07-27 イーライ・リリー・アンド・カンパニー 新規なセフアロスポリン中間体
JPS6117590A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製法
JPS6117591A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製造法
JPS6117587A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製造方法
EP0238060A2 (de) 1986-03-19 1987-09-23 Banyu Pharmaceutical Co., Ltd. Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und antibakterielle Mittel
JPS63152388A (ja) * 1979-11-19 1988-06-24 Fujisawa Pharmaceut Co Ltd 新規なセフェム化合物
JPH0242085A (ja) * 1979-05-25 1990-02-13 Glaxo Group Ltd セフアロスポリン抗生物質の製法
US5675003A (en) * 1995-04-04 1997-10-07 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3006888A1 (de) * 1980-02-23 1981-09-10 Hoechst Ag, 6000 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4336253A (en) 1981-03-11 1982-06-22 Eli Lilly And Company Cephalosporin antibiotics
EP0097961B1 (de) 1982-06-28 1987-11-11 Bristol-Myers Company Cephalosporinderivate, Verfahren zu ihrer Herstellung und pharmazeutische Zusammensetzungen die sie enthalten
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
GB8413152D0 (en) * 1983-06-03 1984-06-27 Ici Pharma Cephalosporin derivatives
US4855420A (en) * 1983-06-03 1989-08-08 Ici Pharma Cephalosporin derivatives
GB8406218D0 (en) * 1984-03-09 1984-04-11 Glaxo Group Ltd Process
FI851934L (fi) * 1984-05-30 1985-12-01 Ici Plc Kefalosporinderivat.
JPH09110877A (ja) 1995-10-17 1997-04-28 Katayama Seiyakushiyo:Kk セフェム化合物、その製造法及びそれを含有する抗菌剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597717B2 (ja) * 1976-09-08 1984-02-20 武田薬品工業株式会社 セフアロスポリン誘導体およびその製造法

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0242085A (ja) * 1979-05-25 1990-02-13 Glaxo Group Ltd セフアロスポリン抗生物質の製法
JPS63152388A (ja) * 1979-11-19 1988-06-24 Fujisawa Pharmaceut Co Ltd 新規なセフェム化合物
JPH0369353B2 (de) * 1979-11-19 1991-10-31 Fujisawa Pharmaceutical Co
JPS5756486A (en) * 1980-08-11 1982-04-05 Fujisawa Pharmaceut Co Ltd Novel cephem compound or its salt, their preparation and prophylactic or remedy for microbism containing the same as active ingredient
JPH0330597B2 (de) * 1980-08-11 1991-04-30
JPS58162592A (ja) * 1982-03-04 1983-09-27 ヘキスト　アクチェンゲゼルシャフト セフアロスポリン誘導体およびその製造方法
JPS5993086A (ja) * 1982-10-23 1984-05-29 バイエル・アクチエンゲゼルシヤフト セフアロスポリン類およびそれらの製造法
JPS59130889A (ja) * 1982-12-27 1984-07-27 イーライ・リリー・アンド・カンパニー 新規なセフアロスポリン中間体
JPH069647A (ja) * 1982-12-27 1994-01-18 Eli Lilly & Co 新規なセファロスポリン中間体
JPS6117587A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製造方法
JPS6117591A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製造法
JPS6117590A (ja) * 1984-04-30 1986-01-25 グラクソ・グル−プ・リミテツド セフアロスポリン化合物の製法
EP0238060A2 (de) 1986-03-19 1987-09-23 Banyu Pharmaceutical Co., Ltd. Cephalosporinverbindungen, Verfahren zu ihrer Herstellung und antibakterielle Mittel
US5675003A (en) * 1995-04-04 1997-10-07 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same

Also Published As

Publication number Publication date
ZA792581B (en) 1981-01-28
CA1132538A (en) 1982-09-28
JPS6354689B2 (de) 1988-10-28
JPS6127921A (ja) 1986-02-07
GB2025398B (en) 1982-08-11
JPS6127989A (ja) 1986-02-07
JPS625916B2 (de) 1987-02-07
CY1168A (en) 1983-06-10
JPS55149289A (en) 1980-11-20
ATA173981A (de) 1982-05-15
KR830000606B1 (ko) 1983-03-17
JPS6127990A (ja) 1986-02-07
KR830000835B1 (ko) 1983-04-20
AT369381B (de) 1982-12-27
JPH0257554B2 (de) 1990-12-05
AT369380B (de) 1982-12-27
GB2058791B (en) 1982-11-24
JPS6322093A (ja) 1988-01-29
ZA807323B (en) 1981-02-25
IT8149648A0 (it) 1981-11-06
BE876538A (fr) 1979-11-26
GB2025398A (en) 1980-01-23
JPH0257073B2 (de) 1990-12-03
GB2058791A (en) 1981-04-15
IT1210588B (it) 1989-09-14
ATA173881A (de) 1982-05-15
HU184631B (en) 1984-09-28
JPH0257069B2 (de) 1990-12-03

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Legal Events

Date Code Title Description
EXPY Cancellation because of completion of term