JPS5148659A - - Google Patents
Info
- Publication number
- JPS5148659A JPS5148659A JP50096316A JP9631675A JPS5148659A JP S5148659 A JPS5148659 A JP S5148659A JP 50096316 A JP50096316 A JP 50096316A JP 9631675 A JP9631675 A JP 9631675A JP S5148659 A JPS5148659 A JP S5148659A
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1002—Tetrapeptides with the first amino acid being neutral
- C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/13—Luteinizing hormone-releasing hormone; related peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Endocrinology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2438350A DE2438350C3 (de) | 1974-08-09 | 1974-08-09 | Peptide mit starker LH-RH/FSH-RH-Wirkung, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5148659A true JPS5148659A (US08124630-20120228-C00102.png) | 1976-04-26 |
| JPS5761268B2 JPS5761268B2 (US08124630-20120228-C00102.png) | 1982-12-23 |
Family
ID=5922833
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP50096316A Expired JPS5761268B2 (US08124630-20120228-C00102.png) | 1974-08-09 | 1975-08-09 |
Country Status (15)
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60218399A (ja) * | 1984-03-27 | 1985-11-01 | ヘキスト・アクチエンゲゼルシヤフト | ペプチド中間体の製法 |
| JPS6299397A (ja) * | 1985-10-22 | 1987-05-08 | リヒタ− ゲデオン ベジエセテイ ジヤ−ル ア−ル．テ−． | 高活性のゴナドリベリン類似体 |
Families Citing this family (52)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2617646C2 (de) * | 1976-04-22 | 1986-07-31 | Hoechst Ag, 6230 Frankfurt | Nonapeptid-amide und Decapeptid-amide mit Gonadoliberin-Wirkung, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate |
| GB1524747A (en) * | 1976-05-11 | 1978-09-13 | Ici Ltd | Polypeptide |
| DE2735515A1 (de) * | 1977-08-06 | 1979-02-22 | Hoechst Ag | Verwendung von lh-rh-peptiden als antikonzeptive |
| FR2450109B1 (fr) * | 1977-11-08 | 1986-03-28 | Roussel Uclaf | Nouvelle methode de traitement utilisant la lh-rh, ou des agonistes |
| US4234571A (en) * | 1979-06-11 | 1980-11-18 | Syntex (U.S.A.) Inc. | Nonapeptide and decapeptide derivatives of luteinizing hormone releasing hormone |
| IT1149971B (it) * | 1979-06-11 | 1986-12-10 | Syntex Inc | Derivati nonapeptide e decapeptide dell'ormone che rilascia l'ormone luteinizzante |
| DE3020941A1 (de) * | 1980-06-03 | 1981-12-17 | Hoechst Ag, 6000 Frankfurt | Nonapeptid, verfahren zu seiner herstellung, dieses enthaltendes mittel und seine verwendung |
| HU185535B (en) * | 1982-05-25 | 1985-02-28 | Mta Koezponti Hivatala | Process for preparing new gonadoliberin derivatives |
| AT390066B (de) * | 1983-03-29 | 1990-03-12 | Richter Gedeon Vegyeszet | Verfahren zur herstellung von neuen gonadoliberin-derivaten |
| HU187503B (en) * | 1983-03-29 | 1986-01-28 | Magyar Tudomanyos Akademia,Hu | Process for preparing gonadoliberine derivatives containing beta-aspartyl group |
| US4775660A (en) * | 1984-08-02 | 1988-10-04 | Fernand Labrie | Treatment of breast cancer by combination therapy |
| US4666885A (en) * | 1985-02-08 | 1987-05-19 | Fernand Labrie | Combination therapy for treatment of female breast cancer |
| US4760053A (en) * | 1984-08-02 | 1988-07-26 | Fernand Labrie | Combination therapy for selected sex steroid dependent cancers |
| HU193093B (en) * | 1985-04-16 | 1987-08-28 | Innofinance | Process for stimulating sexual activity of birds and domestic mammalians and process for producing spermatocytes for their propagation |
| PH30747A (en) * | 1989-03-10 | 1997-10-17 | Endorech Inc | Combination therapy for the treatment of estrogen sensitive disease. |
| US5372996A (en) * | 1989-03-10 | 1994-12-13 | Endorecherche, Inc. | Method of treatment of androgen-related diseases |
| JPH0235232A (ja) * | 1989-06-29 | 1990-02-05 | Nhk Spring Co Ltd | 気室と液室を有する圧力容器 |
| EP0485392B1 (en) * | 1989-07-07 | 1998-09-09 | Endorecherche Inc. | Androgen derivatives for use in the inhibition of sex steroid activity |
| CA2062792C (en) * | 1989-07-07 | 2006-03-21 | Fernard Labrie | Treatment of androgen-related diseases |
| CA2029018A1 (en) * | 1989-11-01 | 1991-05-02 | Robert P. Millar | Analogues of gonadotropin releasing hormone |
| JPH0474770U (US08124630-20120228-C00102.png) * | 1990-10-31 | 1992-06-30 | ||
| KR950701527A (ko) * | 1992-05-21 | 1995-04-28 | 라브리 페르낭 | 테스토스테론 5α 환원효소 활성 저해제(INHIBITORS OF TESTOSTERONE 5α-REDUCTASE ACTIVITY) |
| US7833543B2 (en) * | 1995-06-07 | 2010-11-16 | Durect Corporation | High viscosity liquid controlled delivery system and medical or surgical device |
| US6413536B1 (en) | 1995-06-07 | 2002-07-02 | Southern Biosystems, Inc. | High viscosity liquid controlled delivery system and medical or surgical device |
| CA2192773C (en) | 1995-12-15 | 2008-09-23 | Hiroaki Okada | Production of sustained-release preparation for injection |
| CA2192782C (en) | 1995-12-15 | 2008-10-14 | Nobuyuki Takechi | Production of microspheres |
| US6051558A (en) * | 1997-05-28 | 2000-04-18 | Southern Biosystems, Inc. | Compositions suitable for controlled release of the hormone GnRH and its analogs |
| US20060025328A1 (en) * | 1997-05-28 | 2006-02-02 | Burns Patrick J | Compositions suitable for controlled release of the hormone GnRH and its analogs |
| US6242421B1 (en) | 1997-11-06 | 2001-06-05 | Richard Lloyd Bowen | Methods for preventing and treating Alzheimer's disease |
| ES2154590B1 (es) | 1999-05-20 | 2001-11-01 | Lipotec Sa | Procedimiento de sintesis de peptidos en fase solida |
| AR023940A1 (es) | 2000-05-03 | 2002-09-04 | Eriochem Sa | Procedimiento para la produccion de microcapsulas de liberacion prolongada de peptidos solubles en agua |
| CA2451187C (en) | 2001-06-22 | 2012-08-14 | Southern Biosystems, Inc. | Zero-order prolonged release coaxial implants |
| US20060287282A1 (en) * | 2001-06-25 | 2006-12-21 | Steiner Mitchell S | Compositions comprising a SARM ad GnRH agonist or a GnRH antagonist, and methods of use thereof |
| US20050215528A1 (en) * | 2001-08-10 | 2005-09-29 | Shuichi Furuya | Gnrh agonist combination drugs |
| US7812044B2 (en) | 2001-11-13 | 2010-10-12 | Takeda Pharmaceutical Company Limited | Anticancer agents |
| US20030144203A1 (en) * | 2001-12-19 | 2003-07-31 | Voyager Pharmaceutical Corporation | Methods for slowing senescence and treating and preventing diseases associated with senescence |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| ATE482695T1 (de) * | 2002-12-13 | 2010-10-15 | Durect Corp | Orale darreichungsform mit flüssigen hochviskosen trägersystemen |
| GB0307777D0 (en) * | 2003-04-04 | 2003-05-07 | Medical Res Council | Conjugate compounds |
| LT2767292T (lt) * | 2004-09-17 | 2016-12-12 | Durect Corporation | Palaikomosios vietinės anestezijos mišinys su saib |
| MX2007008781A (es) | 2005-01-21 | 2007-09-11 | Astex Therapeutics Ltd | Compuestos farmaceuticos. |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| US8882747B2 (en) * | 2005-11-09 | 2014-11-11 | The Invention Science Fund I, Llc | Substance delivery system |
| JP5528806B2 (ja) | 2006-10-12 | 2014-06-25 | アステックス、セラピューティックス、リミテッド | 複合薬剤 |
| EP2073807A1 (en) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
| DK2117521T3 (da) | 2006-11-03 | 2012-09-03 | Durect Corp | Transdermale indgivelsessystemer omfattende bupivacain |
| AU2008335809A1 (en) * | 2007-12-06 | 2009-06-18 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| RU2444525C2 (ru) * | 2010-06-09 | 2012-03-10 | Закрытое Акционерное Общество "Фарм-Синтез" | Способ получения нонапептидэтиламида и промежуточные соединения для его получения |
| KR101731008B1 (ko) | 2010-06-16 | 2017-04-27 | 앙도르쉐르슈 인코포레이티드 | 에스트로겐-관련 질병의 치료 또는 예방 방법 |
| TW201521769A (zh) | 2013-03-15 | 2015-06-16 | Durect Corp | 具有流變改質劑以減少溶解變異性之組成物 |
| BR112022013784A2 (pt) | 2020-01-13 | 2022-10-11 | Durect Corp | Sistemas de distribuição de fármacos de liberação prolongada com impurezas reduzidas e métodos relacionados |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50121277A (US08124630-20120228-C00102.png) * | 1974-03-08 | 1975-09-23 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3914412A (en) * | 1973-10-11 | 1975-10-21 | Abbott Lab | {8 Des{13 Gly{9 {0 10 -Gn{13 RH nonapeptide amide analogs in position 6 having ovulation-inducing activity |
| US3901872A (en) * | 1974-03-13 | 1975-08-26 | American Home Prod | P-glu-his-trp-ser-tyr-d-pgl-leu-arg-pro-gly-nh' 2 'and intermediates |
| US3896104A (en) * | 1974-05-22 | 1975-07-22 | American Home Prod | P-glu-his-trp-ser-tyr-d-lys-leu-arg-pro-gly-nh' 2 'and intermediates |
-
1974
- 1974-08-09 DE DE2438350A patent/DE2438350C3/de not_active Expired
-
1975
- 1975-08-04 NL NLAANVRAGE7509260,A patent/NL182051C/xx not_active IP Right Cessation
- 1975-08-05 IL IL47880A patent/IL47880A/xx unknown
- 1975-08-06 CH CH1028175A patent/CH613186A5/xx active Protection Beyond IP Right Term
- 1975-08-07 US US05/602,910 patent/US4024248A/en not_active Expired - Lifetime
- 1975-08-07 LU LU73166A patent/LU73166A1/xx unknown
- 1975-08-07 SE SE7508926A patent/SE424184B/xx not_active IP Right Cessation
- 1975-08-07 CA CA233,179A patent/CA1069888A/en not_active Expired
- 1975-08-08 AT AT0618975A patent/AT364093B/de not_active IP Right Cessation
- 1975-08-08 DK DK361875A patent/DK148905C/da not_active IP Right Cessation
- 1975-08-08 IE IE1771/75A patent/IE41510B1/en unknown
- 1975-08-09 JP JP50096316A patent/JPS5761268B2/ja not_active Expired
- 1975-08-11 FR FR7524951A patent/FR2281132A1/fr active Granted
- 1975-08-11 BE BE159095A patent/BE832310A/xx not_active IP Right Cessation
-
1976
- 1976-08-11 GB GB33426/75A patent/GB1523623A/en not_active Expired
-
1978
- 1978-05-16 SE SE7805545A patent/SE7805545L/sv unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS50121277A (US08124630-20120228-C00102.png) * | 1974-03-08 | 1975-09-23 |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60218399A (ja) * | 1984-03-27 | 1985-11-01 | ヘキスト・アクチエンゲゼルシヤフト | ペプチド中間体の製法 |
| JPS6299397A (ja) * | 1985-10-22 | 1987-05-08 | リヒタ− ゲデオン ベジエセテイ ジヤ−ル ア−ル．テ−． | 高活性のゴナドリベリン類似体 |
Also Published As
| Publication number | Publication date |
|---|---|
| CA1069888A (en) | 1980-01-15 |
| CH613186A5 (US08124630-20120228-C00102.png) | 1979-09-14 |
| IL47880A0 (en) | 1975-11-25 |
| US4024248A (en) | 1977-05-17 |
| BE832310A (fr) | 1976-02-11 |
| DK361875A (da) | 1976-02-10 |
| DK148905C (da) | 1986-04-07 |
| DE2438350C3 (de) | 1979-06-13 |
| LU73166A1 (US08124630-20120228-C00102.png) | 1977-04-13 |
| ATA618975A (de) | 1981-02-15 |
| SE7805545L (US08124630-20120228-C00102.png) | 1978-05-16 |
| DE2438350A1 (de) | 1976-02-26 |
| DE2438350B2 (de) | 1978-10-26 |
| SE424184B (sv) | 1982-07-05 |
| IL47880A (en) | 1978-10-31 |
| IE41510B1 (en) | 1980-01-16 |
| NL7509260A (nl) | 1976-02-11 |
| NL182051C (nl) | 1988-01-04 |
| AU8374475A (en) | 1977-02-10 |
| GB1523623A (en) | 1978-09-06 |
| NL182051B (nl) | 1987-08-03 |
| IE41510L (en) | 1976-02-09 |
| SE7508926L (sv) | 1976-02-10 |
| JPS5761268B2 (US08124630-20120228-C00102.png) | 1982-12-23 |
| FR2281132B1 (US08124630-20120228-C00102.png) | 1979-09-14 |
| FR2281132A1 (fr) | 1976-03-05 |
| AT364093B (de) | 1981-09-25 |
| DK148905B (da) | 1985-11-11 |
