JPH11507026A5 - - Google Patents

Info

Publication number
JPH11507026A5
JPH11507026A5 JP1997500146A JP50014697A JPH11507026A5 JP H11507026 A5 JPH11507026 A5 JP H11507026A5 JP 1997500146 A JP1997500146 A JP 1997500146A JP 50014697 A JP50014697 A JP 50014697A JP H11507026 A5 JPH11507026 A5 JP H11507026A5
Authority
JP
Japan
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997500146A
Other languages
English (en)
Japanese (ja)
Other versions
JP4233113B2 (ja
JPH11507026A (ja
Filing date
Publication date
Priority claimed from GBGB9512827.8A external-priority patent/GB9512827D0/en
Priority claimed from GBGB9513443.3A external-priority patent/GB9513443D0/en
Priority claimed from GBGB9525657.4A external-priority patent/GB9525657D0/en
Application filed filed Critical
Priority claimed from PCT/EP1996/002436 external-priority patent/WO1996040242A1/en
Publication of JPH11507026A publication Critical patent/JPH11507026A/ja
Publication of JPH11507026A5 publication Critical patent/JPH11507026A5/ja
Application granted granted Critical
Publication of JP4233113B2 publication Critical patent/JP4233113B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP50014697A 1995-06-07 1996-06-04 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン Expired - Lifetime JP4233113B2 (ja)

Applications Claiming Priority (9)

Application Number Priority Date Filing Date Title
US47263995A 1995-06-07 1995-06-07
GB9512827.8 1995-06-23
GBGB9512827.8A GB9512827D0 (en) 1995-06-23 1995-06-23 Vaccines
GBGB9513443.3A GB9513443D0 (en) 1995-07-01 1995-07-01 Vaccines
GBGB9525657.4A GB9525657D0 (en) 1995-12-15 1995-12-15 Vaccines
GB08/472,639 1995-12-15
GB9525657.4 1995-12-15
PCT/EP1996/002436 WO1996040242A1 (en) 1995-06-07 1996-06-04 Vaccine comprising a polysaccharide antigen-carrier protein conjugate and free carrier protein
GB9513443.3 1996-07-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2007061946A Division JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Publications (3)

Publication Number Publication Date
JPH11507026A JPH11507026A (ja) 1999-06-22
JPH11507026A5 true JPH11507026A5 (enExample) 2004-07-08
JP4233113B2 JP4233113B2 (ja) 2009-03-04

Family

ID=27451300

Family Applications (2)

Application Number Title Priority Date Filing Date
JP50014697A Expired - Lifetime JP4233113B2 (ja) 1995-06-07 1996-06-04 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン
JP2007061946A Expired - Lifetime JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2007061946A Expired - Lifetime JP4653131B2 (ja) 1995-06-07 2007-03-12 多糖類抗原−キャリア蛋白接合体および遊離キャリア蛋白を有してなるワクチン

Country Status (18)

Country Link
EP (2) EP1090642B8 (enExample)
JP (2) JP4233113B2 (enExample)
AT (2) ATE400295T1 (enExample)
AU (1) AU695720B2 (enExample)
BR (1) BR9608612A (enExample)
CA (1) CA2221511C (enExample)
CZ (1) CZ390297A3 (enExample)
DE (2) DE69615362T3 (enExample)
DK (1) DK1090642T3 (enExample)
ES (2) ES2164251T5 (enExample)
HU (1) HUP9802199A3 (enExample)
IL (1) IL122431A0 (enExample)
NO (1) NO975555L (enExample)
NZ (1) NZ311000A (enExample)
PT (1) PT1090642E (enExample)
SI (1) SI1090642T1 (enExample)
TR (1) TR199701547T1 (enExample)
WO (1) WO1996040242A1 (enExample)

Families Citing this family (71)

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TR199802783T2 (xx) * 1996-07-02 1999-03-22 Connaught Laboratories Limited �ok de�erli DTP polyo a��lar.
US6248334B1 (en) 1997-01-08 2001-06-19 Henry M. Jackson Foundation For The Advancement Of Military Medicine Process for preparing conjugate vaccines including free protein and the conjugate vaccines, immunogens, and immunogenic reagents produced by this process
ATE421339T1 (de) 1998-02-05 2009-02-15 Jackson H M Found Military Med Vereinfachte methode zur entfernung von freiem protein während der herstellung von protein- polysaccharid-konjugaten und impfstoffen unter verwendung von medien mit limitierter durchlässigkeit
US7018637B2 (en) * 1998-02-23 2006-03-28 Aventis Pasteur, Inc Multi-oligosaccharide glycoconjugate bacterial meningitis vaccines
EP1162999B1 (en) 1999-03-19 2006-11-29 Glaxosmithkline Biologicals S.A. Vaccine against Streptococcus pneumoniae
FR2806304B1 (fr) * 2000-03-17 2002-05-10 Aventis Pasteur Conjugues polysaccharidiques du pneumocoque a usage vaccinal contre le tetanos et la diphterie
JP2005504718A (ja) 2001-01-23 2005-02-17 アヴェンティス パストゥール 多価髄膜炎菌多糖−タンパク質複合ワクチン
GB0115176D0 (en) 2001-06-20 2001-08-15 Chiron Spa Capular polysaccharide solubilisation and combination vaccines
DE60335477D1 (de) 2002-10-11 2011-02-03 Novartis Vaccines & Diagnostic Polypeptidimpstoffe zum breiten schutz gegen hypervirulente meningokokken-linien
HUE034801T2 (en) 2002-11-01 2018-02-28 Glaxosmithkline Biologicals Sa Drying procedure
GB0227346D0 (en) 2002-11-22 2002-12-31 Chiron Spa 741
PT2172213E (pt) 2003-01-30 2013-06-03 Novartis Ag Vacinas injetáveis contra múltiplos serogrupos meningocócicos
WO2005030140A2 (en) 2003-09-26 2005-04-07 Exelixis, Inc. C-met modulators and methods of use
ATE506963T1 (de) 2003-10-02 2011-05-15 Novartis Vaccines & Diagnostic Kombinationsimpfstoffe gegen meningitis
GB0323103D0 (en) 2003-10-02 2003-11-05 Chiron Srl De-acetylated saccharides
GB0406013D0 (en) 2004-03-17 2004-04-21 Chiron Srl Analysis of saccharide vaccines without interference
GB0500787D0 (en) 2005-01-14 2005-02-23 Chiron Srl Integration of meningococcal conjugate vaccination
GB0409745D0 (en) 2004-04-30 2004-06-09 Chiron Srl Compositions including unconjugated carrier proteins
JP5718545B2 (ja) 2004-04-30 2015-05-13 ノバルティス ヴァクシンズ アンド ダイアグノスティクス エスアールエル 髄膜炎菌結合体ワクチン接種
GB0411387D0 (en) 2004-05-21 2004-06-23 Chiron Srl Analysis of saccharide length
GB0413868D0 (en) 2004-06-21 2004-07-21 Chiron Srl Dimensional anlaysis of saccharide conjugates
GB0428394D0 (en) * 2004-12-24 2005-02-02 Chiron Srl Saccharide conjugate vaccines
GB0502095D0 (en) 2005-02-01 2005-03-09 Chiron Srl Conjugation of streptococcal capsular saccharides
GB0502096D0 (en) 2005-02-01 2005-03-09 Chiron Srl Purification of streptococcal capsular polysaccharide
GB0505518D0 (en) 2005-03-17 2005-04-27 Chiron Srl Combination vaccines with whole cell pertussis antigen
CA2605179A1 (en) 2005-04-18 2006-10-26 Novartis Vaccines And Diagnostics, Inc. Expressing hepatitis b virus surface antigen for vaccine preparation
PL2878307T3 (pl) 2005-06-27 2020-01-31 Glaxosmithkline Biologicals S.A. Kompozycja immunogenna
CN101287488B (zh) 2005-09-01 2013-01-30 诺华疫苗和诊断有限两合公司 含血清群c脑膜炎球菌的多价疫苗
GB0524066D0 (en) 2005-11-25 2006-01-04 Chiron Srl 741 ii
US10828361B2 (en) 2006-03-22 2020-11-10 Glaxosmithkline Biologicals Sa Regimens for immunisation with meningococcal conjugates
CA2646993C (en) 2006-03-22 2016-01-26 Novartis Ag Regimens for immunisation with meningococcal conjugates
CN103357003A (zh) 2006-09-07 2013-10-23 葛兰素史密丝克莱恩生物有限公司 疫苗
GB0700136D0 (en) 2007-01-04 2007-02-14 Glaxosmithkline Biolog Sa Process for manufacturing vaccines
AU2009309416B2 (en) 2008-10-27 2015-05-28 Glaxosmithkline Biologicals S.A. Purification method
GB0822634D0 (en) 2008-12-11 2009-01-21 Novartis Ag Meningitis vaccines
GB0822633D0 (en) 2008-12-11 2009-01-21 Novartis Ag Formulation
MX373250B (es) 2009-09-30 2020-05-04 Glaxosmithkline Biologicals S A Star Conjugación de polisacáridos capsulares de tipo 5 y de tipo 8 de staphylococcus aureus.
SMT201700275T1 (it) 2009-10-30 2017-07-18 Glaxosmithkline Biologicals Sa Purificazione di saccaridi capsulari di staphylococcus aureus tipo 5 e tipo 8
WO2011080595A2 (en) 2009-12-30 2011-07-07 Novartis Ag Polysaccharide immunogens conjugated to e. coli carrier proteins
WO2012020326A1 (en) 2010-03-18 2012-02-16 Novartis Ag Adjuvanted vaccines for serogroup b meningococcus
WO2012031271A1 (en) 2010-09-04 2012-03-08 Novartis Ag Bactericidal antibody assays to assess immunogenicity and potency of meningococcal capsular saccharide vaccines
GB201101665D0 (en) 2011-01-31 2011-03-16 Novartis Ag Immunogenic compositions
CA2860331A1 (en) 2010-12-24 2012-06-28 Novartis Ag Compounds
US20140112950A1 (en) 2011-03-02 2014-04-24 Manmohan Singh Combination vaccines with lower doses of antigen and/or adjuvant
GB201106340D0 (en) * 2011-04-14 2011-06-01 Isis Innovation Composition
CN103917245B (zh) 2011-09-14 2017-06-06 葛兰素史密丝克莱恩生物有限公司 用于制备糖‑蛋白质糖缀合物的方法
JP6170932B2 (ja) 2011-11-07 2017-07-26 ノバルティス アーゲー spr0096抗原およびspr2021抗原を含むキャリア分子
EP2592137A1 (en) 2011-11-11 2013-05-15 Novartis AG Fermentation media free of animal-derived components for production of diphtheria toxoids suitable for human vaccine use
DE102011122891B4 (de) 2011-11-11 2014-12-24 Novartis Ag Fermentationsmedium, das frei von tierischen Bestandteilen ist, zur Herstellung von Diphtherie-Toxoiden zur Verwendung bei der Impfung von Menschen
GB2495341B (en) 2011-11-11 2013-09-18 Novartis Ag Fermentation methods and their products
DE102011118371B4 (de) 2011-11-11 2014-02-13 Novartis Ag Zur Impfung von Menschen geeignete Zusammensetzung, die ein Diphtherie-Toxoid umfasst, sowie Verfahren zu deren Herstellung
GB201121301D0 (en) 2011-12-12 2012-01-25 Novartis Ag Method
US20150125486A1 (en) 2012-03-08 2015-05-07 Novartis Ag Adjuvanted formulations of pediatric antigens
AU2013265336A1 (en) 2012-05-22 2014-12-04 Novartis Ag Meningococcus serogroup X conjugate
RU2015106930A (ru) 2012-09-06 2016-10-20 Новартис Аг Комбинированные вакцины с менингококком серогруппы в и к/д/с
SG11201500978TA (en) 2012-10-03 2015-07-30 Glaxosmithkline Biolog Sa Immunogenic compositions
EP2906239A1 (en) 2012-10-12 2015-08-19 GlaxoSmithKline Biologicals SA Non-cross-linked acellular pertussis antigens for use in combination vaccines
US20150320852A1 (en) 2012-12-18 2015-11-12 Glaxosmithkline Biologicals Sa Conjugates for protecting against diphtheria and/or tetanus
CA3044471C (en) * 2013-01-04 2021-05-11 Obi Pharma, Inc. Vaccines with higher carbohydrate antigen density and novel saponin adjuvant
CN104174019A (zh) * 2014-09-23 2014-12-03 成都康华生物制品有限公司 四价脑膜炎球菌多糖载体蛋白结合疫苗
US9107906B1 (en) 2014-10-28 2015-08-18 Adma Biologics, Inc. Compositions and methods for the treatment of immunodeficiency
EP3034516A1 (en) 2014-12-19 2016-06-22 Novartis AG Purification of streptococcal capsular polysaccharide
EP3439704A1 (en) 2016-04-05 2019-02-13 GSK Vaccines S.r.l. Immunogenic compositions
JP6944946B2 (ja) 2016-10-20 2021-10-06 Kmバイオロジクス株式会社 低分子化PRPを用いたHibコンジュゲートワクチンの製造方法
US10259865B2 (en) 2017-03-15 2019-04-16 Adma Biologics, Inc. Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection
EP3799884A1 (en) 2019-10-01 2021-04-07 GlaxoSmithKline Biologicals S.A. Immunogenic compositions
US11173199B2 (en) * 2019-11-13 2021-11-16 Alopexx Inc. Low contaminant compositions
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