JPH1129545A5 - - Google Patents

Info

Publication number
JPH1129545A5
JPH1129545A5 JP1997202756A JP20275697A JPH1129545A5 JP H1129545 A5 JPH1129545 A5 JP H1129545A5 JP 1997202756 A JP1997202756 A JP 1997202756A JP 20275697 A JP20275697 A JP 20275697A JP H1129545 A5 JPH1129545 A5 JP H1129545A5
Authority
JP
Japan
Prior art keywords
alkyl
aryl
alkylaryl
formula
substituted aryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1997202756A
Other languages
English (en)
Japanese (ja)
Other versions
JP4039589B2 (ja
JPH1129545A (ja
Filing date
Publication date
Priority claimed from EP96112275A external-priority patent/EP0837055A1/en
Application filed filed Critical
Publication of JPH1129545A publication Critical patent/JPH1129545A/ja
Publication of JPH1129545A5 publication Critical patent/JPH1129545A5/ja
Application granted granted Critical
Publication of JP4039589B2 publication Critical patent/JP4039589B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP20275697A 1996-07-30 1997-07-29 置換インダニリジンアセチルグアニジン類、それらの製造方法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬 Expired - Fee Related JP4039589B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP96112275A EP0837055A1 (en) 1996-07-30 1996-07-30 Substituted Indanylidineacetylguanidines, process for their preparation, their use as medicaments or diagnostic and medicaments containing them
DE96112275:1 1996-07-30

Publications (3)

Publication Number Publication Date
JPH1129545A JPH1129545A (ja) 1999-02-02
JPH1129545A5 true JPH1129545A5 (https=) 2005-05-26
JP4039589B2 JP4039589B2 (ja) 2008-01-30

Family

ID=8223055

Family Applications (1)

Application Number Title Priority Date Filing Date
JP20275697A Expired - Fee Related JP4039589B2 (ja) 1996-07-30 1997-07-29 置換インダニリジンアセチルグアニジン類、それらの製造方法、医薬または診断剤としてのそれらの使用およびそれらを含有する医薬

Country Status (29)

Country Link
US (1) US5900436A (https=)
EP (2) EP0837055A1 (https=)
JP (1) JP4039589B2 (https=)
KR (1) KR980009236A (https=)
CN (1) CN1064351C (https=)
AR (1) AR008095A1 (https=)
AT (1) ATE207888T1 (https=)
AU (1) AU715187B2 (https=)
BR (1) BR9704131A (https=)
CA (1) CA2211982C (https=)
CZ (1) CZ241197A3 (https=)
DE (1) DE69707777T2 (https=)
DK (1) DK0822182T3 (https=)
ES (1) ES2164283T3 (https=)
HR (1) HRP970424B1 (https=)
HU (1) HUP9701316A3 (https=)
ID (1) ID17565A (https=)
IL (1) IL121407A0 (https=)
MX (1) MX9705737A (https=)
NO (1) NO308213B1 (https=)
NZ (1) NZ328440A (https=)
PL (1) PL321392A1 (https=)
PT (1) PT822182E (https=)
RU (1) RU2176638C2 (https=)
SI (1) SI0822182T1 (https=)
SK (1) SK282128B6 (https=)
TR (1) TR199700704A2 (https=)
TW (1) TW445251B (https=)
ZA (1) ZA976735B (https=)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX381407B (es) 2008-12-31 2025-03-12 Ardelyx Inc Compuestos y métodos para inhibir el antiporte mediado por intercambiador de iones de sodio/iones de hidrógeno (nhe) en el tratamiento de trastornos asociados con retención de fluido o sobrecarga de sal y trastornos del tracto gastrointestinal.
WO2018129556A1 (en) 2017-01-09 2018-07-12 Ardelyx, Inc. Compounds and methods for inhibiting nhe-mediated antiport in the treatment of disorders associated with fluid retention or salt overload and gastrointestinal tract disorders
GB0916163D0 (en) * 2009-09-15 2009-10-28 Shire Llc Prodrugs of guanfacine
HRP20191000T1 (hr) 2013-04-12 2019-09-20 Ardelyx, Inc. Spojevi za vezanje nhe3 i metode inhibiranja transporta fosfata
MX395405B (es) 2017-01-09 2025-03-25 Ardelyx Inc Compuestos útiles para tratar trastornos del tracto gastrointestinal.
MX2019008171A (es) 2017-01-09 2020-02-05 Ardelyx Inc Inhibidores del antiporte mediado por nhe.
EP4706758A3 (en) 2019-05-21 2026-05-06 Ardelyx, Inc. Methods for inhibiting phosphate transport
CN116492469A (zh) * 2023-05-22 2023-07-28 遵义医科大学附属医院 一种通道阻滞剂在制备治疗和/或预防肝纤维疾病药物中的应用
CN119118881B (zh) * 2024-07-25 2026-01-02 中国农业大学 含胍基的5-氯茚满化合物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
DE4421536A1 (de) * 1994-06-20 1995-12-21 Hoechst Ag Perfluoralkylgruppen tragende phenylsubstituierte Alkenylcarbonsäure-guanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
EP0738712B1 (en) * 1995-04-18 1999-08-18 Hoechst Aktiengesellschaft Anti-arrhythmic and cardioprotective substituted indenoylguanidines

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