JPH10507406A - 不混和性流体間の拡散移動のための方法及び装置 - Google Patents
不混和性流体間の拡散移動のための方法及び装置Info
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Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.第1不混和性流体と第2不混和性流体の間での拡散移動工程を実施するた めの装置であって、有孔シート手段の両側に配置された第1及び第2流体のそれ ぞれのための第1及び第2流路を具備し、界面に隣接して各流体の実質的な成分 の流体流れが可能になるように、前記シート手段が使用の際に前記流体間の界面 が各開口部に又は開口部内に形成されるようなものであり、そして界面で流体流 れの方向及びシート手段の厚さ方向の双方に垂直な方向において測定した場合に 少なくとも開口部のより大きな部分のそれぞれの高さが200マイクロメートル 以下である装置。 2.前記高さが1〜30マイクロメートルである請求項1記載の装置。 3.シート手段の領域におけるシート手段に垂直な方向の第1及び第2流体流 路の幅(1)が、(a)10〜500マイクロメートル、又は(b)以下の不等 式: 12<D・t・x-1 (Dは各流体の拡散係数であり、tはシート手段の領域内での各流体の滞留時間 であり、そしてxは0.005以上の値を有する定数である) により決定される所定の値以下のいずれかである、請求項1又は2のいずれか一 項に記載の装置。 4.xが0.01以上の値を有する請求項3記載の装置。 5.xが0.1以上の値を有する請求項3記載の装置。 6.第3流体のための第3流路及び第2シート手段を具備し、前記第3流路が 前記第2シート手段を通って第1又は第2流路と連通し、前記第3流体が第1又 は第2流体のそれぞれと不混和性である 、請求項1〜5のいずれか一項に記載の装置。 7.シート手段が立体構造物中に組み込まれて形成された請求項1〜6のいず れか一項に記載の装置。 8.前記構造物が、前記シート手段からなるシート部分により分けられた一連 のブロック部材を具備し、前記ブロック部材が前記シート部分のための支持体を 形成している、請求項7記載の装置。 9.シート手段が、メッシュ、有孔シート、又は多孔質膜として形成された、 請求項1〜6のいずれか一項に記載の装置。 10.シートが、間隔を置いて配置された開口部を具備するようにエッチングさ れた固体平面シートから形成された、請求項9記載の装置。 11.シートか、一方の層が他方の層とは異なる表面特性若しくは導電性又は他 の内部特性を有する第1及び第2シート層から形成された、請求項9又は10のい ずれか一項に記載の装置。 12.第1層が親水性であり、且つ第2層が疎水性であるか、又は、第1層が電 気的に絶縁性であり、且つ第2層が導電性である、請求項11記載の装置。 13.第3層を具備し、第1層と第3層の間に配置された第2層を有する、請求 項11又は12のいずれか一項に記載の装置。 14.各開口部の内壁がシート手段の幅の方向に対して本質的に平行であり、そ して前記シート手段の厚さ方向を横切る開口部の幅の開口部の高さに対するアス ペクト比が1以下である、請求項1〜13のいずれか一項に記載の装置。 15.開口部が片側の端においてもう一方の端よりも広くなるように各開口部の 壁にテーパーがつけられた、請求項1〜13のいずれか一項に記載の装置。 16.開口部の中央領域に高さが最低の開口部領域を具備するよう に、各開口部の内壁が各端から内側にテーパーがつけられた、請求項1〜13のい ずれか一項に記載の装置。 17.シートの面を横切って流体を運ぶ溝内の流れの方向に開口部が延びている 、請求項1〜16のいずれか一項に記載の装置。 18.シート手段が、第1及び第2流体をモニターするため又は第1及び第2流 体に影響を及ぼすための電極手段を具備し、且つカウンター及び/又は参照電極 手段を具備している、請求項1〜17のいずれか一項に記載の装置。 19.第1流体から第1流体とは不混和性の第2流体への存在物の拡散移動の工 程を実施するための方法であって、 (1)有孔シート手段を通して互いに連通している第1及び第2流路を提供す ること、ただし当該シート手段内の開口部の少なくとも大きい部分の高さは界面 位置で流体流れの方向及び当該シート手段の幅の方向の双方に垂直な方向におい て測定した場合に各々200マイクロメートル以下である; (2)少なくともシート手段の領域で、流体の流れが本質的に層流であり、且 つ安定な界面がシート手段の開口部又は開口部内の前記界面位置で形成され、各 流体の流体流れの実質的な成分が界面に隣接するように、第1及び第2流路の各 々に第1及び第2流体を流すこと; (3)移動しうる前記存在物の合計量の実質的な量(少なくとも1%)を拡散 移動させること;次いで (4)流体を混合させずにシート手段から各流路に流出させること; を含む方法。 20.前記高さが1〜30マイクロメートルである請求項19記載の方法。 21.シート手段の領域におけるシート手段に垂直な方向の第1及び第2流体流 路の幅(1)が、(a)10〜500マイクロメートル、又は(b)以下の不等 式 12<D・t・x-1 (Dは各流体の拡散係数であり、tはシート手段の領域内での各流体の滞留時間 であり、そしてxは0.005以上の値を有する定数である) により決定される所定の値以下のいずれかである、請求項19又は20のいずれか一 項に記載の方法。 22.xが0.01以上の値を有する請求項21記載の方法。 23.xが0.1以上の値を有する請求項21記載の方法。 24.第3流体のための第3流路及び第2シート手段を具備し、前記第3流路が 前記第2シート手段を通って第1又は第2流路と連通し、前記第3流体が第1又 は第2流体のそれぞれと不混和性である、請求項19〜23のいずれか一項に記載の 方法。 25.シート手段が立体構造物中に組み込まれて形成される請求項19〜24のいず れか一項に記載の方法。 26.前記構造物が、前記シート手段からなるシート部分により分けられた一連 のブロック部材を具備し、前記ブロック部材が前記シート部分のための支持体を 形成する、請求項25記載の方法。 27.シート手段が、メッシュ、有孔シート、又は多孔質膜として形成される、 請求項19〜25のいずれか一項に記載の方法。 28.シートが、間隔を置いて配置された開口部を具備するようにエッチングさ れた固体平面シートから形成される、請求項27記載の方法。 29.シートが、一方の層が他方の層とは異なる表面特性若しくは導電性又は他 の内部特性を有する第1及び第2シート層から形成さ れる、請求項27又は28のいずれか一項に記載の方法。 30.第3層を提供し、第1層と第3層の間に第2層を配置させる、請求項29記 載の方法。 31.第1層が親水性であり、且つ第2層が疎水性であるか、又は第1層が電気 的に絶縁性であり、且つ第2層が導電性である、請求項29又は30のいずれか一項 に記載の方法。 32.各開口部の内壁がシート手段の幅の方向に対して本質的に平行であり、そ して前記シート手段を横切る開口部の幅の開口部の高さに対するアスペクト比が 1以下である、請求項19〜31のいずれか一項に記載の方法。 33.開口部が片側の端においてもう一方の端よりも広くなるように各開口部の 壁にテーパーがつけられた、請求項19〜31のいずれか一項に記載の方法。 34.開口部の中央領域に高さが最低の開口部領域を具備するように、各開口部 の内壁が各端から内側にテーパーかつけられた、請求項19〜31のいずれか一項に 記載の方法。 35.シートの面を横切って流体を運ぶ溝内の流れの方向に開口部が延びる、請 求項19〜34のいずれか一項に記載の方法。 36.シート手段が、電極手段及びカウンター及び/又は参照電極手段により第 1及び第2流体をモニター又は第1及び第2流体に影響を及ぼすことを含む、請 求項19〜35のいずれか一項に記載の方法。
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9421313.9 | 1994-10-22 | ||
GB9421313A GB9421313D0 (en) | 1994-10-22 | 1994-10-22 | Method and apparatus for process |
GBGB9515357.3A GB9515357D0 (en) | 1995-07-26 | 1995-07-26 | Method and apparatus for process |
GB9515357.3 | 1995-07-26 | ||
PCT/GB1995/002488 WO1996012540A1 (en) | 1994-10-22 | 1995-10-20 | Method and apparatus for diffusive transfer between immiscible fluids |
Publications (2)
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JP4015187B2 JP4015187B2 (ja) | 2007-11-28 |
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EP (1) | EP0787029B1 (ja) |
JP (1) | JP4015187B2 (ja) |
KR (1) | KR100367063B1 (ja) |
CN (1) | CN1088385C (ja) |
AT (1) | ATE175362T1 (ja) |
AU (1) | AU695237B2 (ja) |
CA (1) | CA2203283A1 (ja) |
DE (1) | DE69507157T2 (ja) |
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JP2006272231A (ja) * | 2005-03-30 | 2006-10-12 | Hitachi Ltd | マイクロ流路 |
JP2014087747A (ja) * | 2012-10-30 | 2014-05-15 | Mitsui Eng & Shipbuild Co Ltd | 液間溶質移送装置及び液間溶質移送方法 |
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Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2001281233A (ja) * | 2000-03-28 | 2001-10-10 | Inst Of Physical & Chemical Res | 水性分配用マイクロチップおよびそれを用いた水性分配方法 |
WO2002075324A1 (fr) * | 2001-03-15 | 2002-09-26 | Kanagawa Academy Of Science And Technology | Procede de fabrication d'un corps structurel a micro-canaux et film de polymere a haute fonctionnalite |
JP2005007352A (ja) * | 2003-06-20 | 2005-01-13 | Sharp Corp | 粒子の分離方法及び分離装置並びに検出装置 |
JP2006272231A (ja) * | 2005-03-30 | 2006-10-12 | Hitachi Ltd | マイクロ流路 |
JP4481859B2 (ja) * | 2005-03-30 | 2010-06-16 | 株式会社日立製作所 | マイクロ流路 |
JP2014087747A (ja) * | 2012-10-30 | 2014-05-15 | Mitsui Eng & Shipbuild Co Ltd | 液間溶質移送装置及び液間溶質移送方法 |
Also Published As
Publication number | Publication date |
---|---|
KR100367063B1 (ko) | 2003-02-19 |
EP0787029B1 (en) | 1999-01-07 |
CA2203283A1 (en) | 1996-05-02 |
JP4015187B2 (ja) | 2007-11-28 |
KR970706875A (ko) | 1997-12-01 |
ATE175362T1 (de) | 1999-01-15 |
CN1161659A (zh) | 1997-10-08 |
DE69507157D1 (de) | 1999-02-18 |
EP0787029A1 (en) | 1997-08-06 |
DE69507157T2 (de) | 1999-09-02 |
US5961832A (en) | 1999-10-05 |
AU695237B2 (en) | 1998-08-13 |
WO1996012540A1 (en) | 1996-05-02 |
ES2130659T3 (es) | 1999-07-01 |
CN1088385C (zh) | 2002-07-31 |
AU3703095A (en) | 1996-05-15 |
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