JPH10504027A - ＮＭＤＡ拮抗物質としての４−ヒドロキシ−３−フェニル−インデノ（１，２−ｂ）ピリジン−２（１Ｈ）−オン誘導体類 - Google Patents

ＮＭＤＡ拮抗物質としての４−ヒドロキシ−３−フェニル−インデノ（１，２−ｂ）ピリジン−２（１Ｈ）−オン誘導体類

Info

Publication number
JPH10504027A
JPH10504027A JP8504757A JP50475796A JPH10504027A JP H10504027 A JPH10504027 A JP H10504027A JP 8504757 A JP8504757 A JP 8504757A JP 50475796 A JP50475796 A JP 50475796A JP H10504027 A JPH10504027 A JP H10504027A
Authority
JP
Japan
Prior art keywords
group
formula
alkyl
atom
alk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP8504757A
Other languages
English (en)
Japanese (ja)
Inventor
ジヤン−クロード アルー，
フランソワ オデイオ，
ミシエル バロ，
ドミニク ダムール，
アリエル ジユヌボワ−ボレラ，
パトリク ジモネ，
セルジユ ミニヤニ，
イブ リベーユ，
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH10504027A publication Critical patent/JPH10504027A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/06—Ring systems of three rings
    • C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP8504757A 1994-07-20 1995-07-17 ＮＭＤＡ拮抗物質としての４−ヒドロキシ−３−フェニル−インデノ（１，２−ｂ）ピリジン−２（１Ｈ）−オン誘導体類 Pending JPH10504027A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR94/08999 1994-07-20
FR9408999A FR2722786B1 (fr) 1994-07-20 1994-07-20 Derives de 4-hydroxy-3-phenyl-indeno(1,2-b)pyridine-2(1h)- one, leur preparation et les medicaments les contenant
PCT/FR1995/000952 WO1996002536A1 (fr) 1994-07-20 1995-07-17 Derives de 4-hydroxy-3-phenyl-indeno(1,2-b)pyridine-2(1h)-one comme nmda antagonistes

Publications (1)

Publication Number Publication Date
JPH10504027A true JPH10504027A (ja) 1998-04-14

Family

ID=9465588

Family Applications (1)

Application Number Title Priority Date Filing Date
JP8504757A Pending JPH10504027A (ja) 1994-07-20 1995-07-17 ＮＭＤＡ拮抗物質としての４−ヒドロキシ−３−フェニル−インデノ（１，２−ｂ）ピリジン−２（１Ｈ）−オン誘導体類

Country Status (6)

Country Link
EP (1) EP0772612A1 (xx)
JP (1) JPH10504027A (xx)
AU (1) AU2984695A (xx)
FR (1) FR2722786B1 (xx)
WO (1) WO1996002536A1 (xx)
ZA (1) ZA955942B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030082982A (ko) * 2001-03-14 2003-10-23 그뤼넨탈 게엠베하 치환된 피라졸로피리미딘 및 티아졸로피리미딘
WO2015088564A1 (en) * 2013-12-13 2015-06-18 Sunovion Pharmaceuticals Inc. P2x4 receptor modulating compounds
WO2015088565A1 (en) * 2013-12-13 2015-06-18 Sunovion Pharmaceuticals Inc. P2x4 receptor modulating compounds and methods of use thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA903588B (en) * 1989-05-16 1991-02-27 Merrell Dow Pharma Excitatory amino acid antagonists
GB9022785D0 (en) * 1990-10-19 1990-12-05 Merck Sharp & Dohme Therapeutic agents

Also Published As

Publication number Publication date
WO1996002536A1 (fr) 1996-02-01
EP0772612A1 (fr) 1997-05-14
AU2984695A (en) 1996-02-16
FR2722786A1 (fr) 1996-01-26
FR2722786B1 (fr) 1996-08-23
ZA955942B (en) 1996-02-21

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