JPH0772171B2 - 心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物 - Google Patents

心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物

Info

Publication number
JPH0772171B2
JPH0772171B2 JP61169673A JP16967386A JPH0772171B2 JP H0772171 B2 JPH0772171 B2 JP H0772171B2 JP 61169673 A JP61169673 A JP 61169673A JP 16967386 A JP16967386 A JP 16967386A JP H0772171 B2 JPH0772171 B2 JP H0772171B2
Authority
JP
Japan
Prior art keywords
mol
bis
fluorophenyl
pharmaceutically acceptable
acceptable salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP61169673A
Other languages
English (en)
Japanese (ja)
Other versions
JPS62169763A (ja
Inventor
ジェームス・ロバート・シャンクリン・ジュニアー
アントニー・ジョージ・プロアキンス
Original Assignee
エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド filed Critical エイ・エイチ・ロビンス・カンパニー・インコーポレーテッド
Publication of JPS62169763A publication Critical patent/JPS62169763A/ja
Publication of JPH0772171B2 publication Critical patent/JPH0772171B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
JP61169673A 1986-01-17 1986-07-18 心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物 Expired - Lifetime JPH0772171B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81970186A 1986-01-17 1986-01-17
US819701 1986-01-17

Publications (2)

Publication Number Publication Date
JPS62169763A JPS62169763A (ja) 1987-07-25
JPH0772171B2 true JPH0772171B2 (ja) 1995-08-02

Family

ID=25228814

Family Applications (1)

Application Number Title Priority Date Filing Date
JP61169673A Expired - Lifetime JPH0772171B2 (ja) 1986-01-17 1986-07-18 心血管薬、抗ヒスタミン薬および分泌抑制薬としてのｎ−置換−アリ−ルアルキル−および−アリ−ルアルキレン−アミノ複素環化合物

Country Status (11)

Country Link
JP (1) JPH0772171B2 (en, 2012)
KR (1) KR900005368B1 (en, 2012)
AU (1) AU594972B2 (en, 2012)
DK (1) DK347986A (en, 2012)
GR (1) GR862024B (en, 2012)
IL (1) IL78939A (en, 2012)
IN (1) IN163948B (en, 2012)
NZ (1) NZ217408A (en, 2012)
PH (3) PH23843A (en, 2012)
PT (1) PT84128B (en, 2012)
ZA (1) ZA864522B (en, 2012)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH23283A (en) * 1986-02-26 1989-06-30 Eisai Co Ltd Piperidine derivative, pharmaceutical composition containing the same and method of use thereof
KR890012971A (ko) * 1988-02-10 1989-09-20 원본미기재 심장혈관 항히스타민제 및 분비억제제로서의 n-치환된-아릴알킬 및 아릴알킬렌 아미노헤테로사이클릭 화합물
AU629534B2 (en) * 1988-02-24 1992-10-08 A.H. Robins Company, Incorporated New methods and related compounds
GB8825505D0 (en) * 1988-11-01 1988-12-07 Pfizer Ltd Therapeutic agents
GB8906166D0 (en) * 1989-03-17 1989-05-04 Pfizer Ltd Therapeutic agents
GB8928042D0 (en) * 1989-12-12 1990-02-14 Pfizer Ltd Muscarinic receptor antagonists
US6004980A (en) * 1990-06-01 1999-12-21 Merrell Pharmaceuticals, Inc. (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl)ethyl]-4-piperidinemethanol
PH31566A (en) * 1990-10-10 1998-11-03 Schering Corp Pyridine and pyridine n-oxide derivatives for diaryl methyl piperidines or piperazines and compositions and methods of use thereof.
DE4111861A1 (de) * 1991-04-11 1992-10-15 Schwabe Willmar Gmbh & Co Benzopyranone, verfahren zu ihrer herstellung und verwendung
AU2931792A (en) * 1991-11-29 1993-06-28 Zeria Pharmaceutical Co., Ltd. Piperidine derivative and medicine containing the same
US5681830A (en) * 1992-02-03 1997-10-28 Delta Pharmaceuticals, Inc. Opioid compounds
US5807858A (en) * 1996-06-05 1998-09-15 Delta Pharmaceutical, Inc. Compositions and methods for reducing respiratory depression
ATE140224T1 (de) * 1992-03-27 1996-07-15 Schering Corp Unverbrückte bis-aryl-carbinol-derivate, zusammensetzungen und ihre verwendung
HUT71132A (en) * 1992-03-27 1995-11-28 Schering Corp Bis-aryl-carbinol derivatives, pharmaceutical compositions containing them and process for producing
JPH09501156A (ja) 1993-07-30 1997-02-04 ザ．ウェルカム．ファウンデーション．リミテッド 治療法で使用するピペラジン化合物
JP4057088B2 (ja) * 1996-04-22 2008-03-05 株式会社カネカ ピロリジン誘導体の製造方法
US6028083A (en) * 1997-07-25 2000-02-22 Hoechst Marion Roussel, Inc. Esters of (+)-α-(2,3-dimethoxyphenyl)-1-[2-(4-fluorophenyl) ethyl]-4-piperidinemethanol
TW200510298A (en) * 2003-06-13 2005-03-16 Theravance Inc Substituted pyrrolidine and related compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4035372A (en) * 1976-08-13 1977-07-12 G. D. Searle & Co. 4-{[4-(Diphenylmethyl)-1-piperidinyl]methyl}benzenamines
US4632925A (en) * 1985-10-07 1986-12-30 Hoffmann-La Roche Inc. N-substituted diphenylpiperidines and antiobesity use thereof
US4810713A (en) * 1985-12-20 1989-03-07 A. H. Robins Company, Incorporated Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl groups used in a method for allergy treatment

Also Published As

Publication number Publication date
NZ217408A (en) 1990-03-27
PH23843A (en) 1989-11-23
JPS62169763A (ja) 1987-07-25
IN163948B (en, 2012) 1988-12-10
PT84128B (pt) 1989-05-31
AU594972B2 (en) 1990-03-22
KR870007131A (ko) 1987-08-17
KR900005368B1 (ko) 1990-07-28
PT84128A (en) 1987-02-01
IL78939A0 (en) 1986-09-30
PH24983A (en) 1990-12-26
PH24904A (en) 1990-12-26
GR862024B (en) 1986-12-24
AU6247386A (en) 1987-07-23
IL78939A (en) 1990-04-29
DK347986A (da) 1987-07-18
ZA864522B (en) 1987-02-25
DK347986D0 (da) 1986-07-22

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