JPH07505618A - ３−アシルアンドロスタジエンの製法 - Google Patents

３−アシルアンドロスタジエンの製法

Info

Publication number
JPH07505618A
JPH07505618A JP5514211A JP51421193A JPH07505618A JP H07505618 A JPH07505618 A JP H07505618A JP 5514211 A JP5514211 A JP 5514211A JP 51421193 A JP51421193 A JP 51421193A JP H07505618 A JPH07505618 A JP H07505618A
Authority
JP
Japan
Prior art keywords
formula
compound
tables
reaction
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP5514211A
Other languages
English (en)
Japanese (ja)
Inventor
ベイン，ニール・ハワード
マクガイア，マイケル
Original Assignee
スミスクライン・ビーチャム・コーポレイション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by スミスクライン・ビーチャム・コーポレイション filed Critical スミスクライン・ビーチャム・コーポレイション
Publication of JPH07505618A publication Critical patent/JPH07505618A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP5514211A 1992-02-07 1993-02-05 ３−アシルアンドロスタジエンの製法 Pending JPH07505618A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83227992A 1992-02-07 1992-02-07
US832,279 1992-02-07
PCT/US1993/001071 WO1993016098A1 (en) 1992-02-07 1993-02-05 Process of preparing 3-acylandrostadienes

Publications (1)

Publication Number Publication Date
JPH07505618A true JPH07505618A (ja) 1995-06-22

Family

ID=25261205

Family Applications (1)

Application Number Title Priority Date Filing Date
JP5514211A Pending JPH07505618A (ja) 1992-02-07 1993-02-05 ３−アシルアンドロスタジエンの製法

Country Status (13)

Country Link
EP (1) EP0626972A4 (zh)
JP (1) JPH07505618A (zh)
KR (1) KR950700320A (zh)
CN (1) CN1078474A (zh)
AU (1) AU3612893A (zh)
CA (1) CA2129347A1 (zh)
IL (1) IL104601A0 (zh)
MA (1) MA22787A1 (zh)
MX (1) MX9300677A (zh)
SI (1) SI9300067A (zh)
TW (1) TW241266B (zh)
WO (1) WO1993016098A1 (zh)
ZA (1) ZA93802B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104602A (en) * 1992-02-07 1997-07-13 Smithkline Beecham Corp Process for the preparation of 3-carbonylandrostadiene- 17-carboxamides and intermediates for this process
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946834A (en) * 1988-12-23 1990-08-07 Smithkline Beecham Corporation Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase
US5091380A (en) * 1990-06-28 1992-02-25 Merck & Co., Inc. N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors

Also Published As

Publication number Publication date
EP0626972A1 (en) 1994-12-07
IL104601A0 (en) 1993-07-08
MX9300677A (es) 1994-07-29
TW241266B (zh) 1995-02-21
KR950700320A (ko) 1995-01-16
ZA93802B (en) 1993-11-05
CN1078474A (zh) 1993-11-17
EP0626972A4 (en) 1995-01-04
MA22787A1 (fr) 1993-10-01
WO1993016098A1 (en) 1993-08-19
AU3612893A (en) 1993-09-03
SI9300067A (en) 1993-09-30
CA2129347A1 (en) 1993-08-19

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