ZA93802B - Process for the preparation of substituted steroidal dienes - Google Patents

Process for the preparation of substituted steroidal dienes

Info

Publication number
ZA93802B
ZA93802B ZA93802A ZA93802A ZA93802B ZA 93802 B ZA93802 B ZA 93802B ZA 93802 A ZA93802 A ZA 93802A ZA 93802 A ZA93802 A ZA 93802A ZA 93802 B ZA93802 B ZA 93802B
Authority
ZA
South Africa
Prior art keywords
preparation
substituted steroidal
dienes
steroidal dienes
substituted
Prior art date
Application number
ZA93802A
Other languages
English (en)
Inventor
Neil Howard Baine
Michael Maguire
Original Assignee
Smithkline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corp filed Critical Smithkline Beecham Corp
Publication of ZA93802B publication Critical patent/ZA93802B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0066—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by a carbon atom forming part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J3/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom
    • C07J3/005—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by one carbon atom the carbon atom being part of a carboxylic function

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA93802A 1992-02-07 1993-02-05 Process for the preparation of substituted steroidal dienes ZA93802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83227992A 1992-02-07 1992-02-07

Publications (1)

Publication Number Publication Date
ZA93802B true ZA93802B (en) 1993-11-05

Family

ID=25261205

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA93802A ZA93802B (en) 1992-02-07 1993-02-05 Process for the preparation of substituted steroidal dienes

Country Status (13)

Country Link
EP (1) EP0626972A4 (zh)
JP (1) JPH07505618A (zh)
KR (1) KR950700320A (zh)
CN (1) CN1078474A (zh)
AU (1) AU3612893A (zh)
CA (1) CA2129347A1 (zh)
IL (1) IL104601A0 (zh)
MA (1) MA22787A1 (zh)
MX (1) MX9300677A (zh)
SI (1) SI9300067A (zh)
TW (1) TW241266B (zh)
WO (1) WO1993016098A1 (zh)
ZA (1) ZA93802B (zh)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL104602A (en) * 1992-02-07 1997-07-13 Smithkline Beecham Corp Process for the preparation of 3-carbonylandrostadiene- 17-carboxamides and intermediates for this process
US5683995A (en) * 1992-11-18 1997-11-04 Smithkline Beecham Corporation 17 substituted acyl-3-carboxy 3,5-diene steroidals as α-reductase inhibitors
US5641765A (en) * 1992-11-18 1997-06-24 Smithkline Beecham Corporation 17-αand 17-βsubstituted acyl-3-carboxy-3,5-dienes and use in inhibiting 5-α-reductase

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4946834A (en) * 1988-12-23 1990-08-07 Smithkline Beecham Corporation Phosphonic acid substituted steroids as steroid 5α-reductase inhibitors
US5032586A (en) * 1989-08-24 1991-07-16 Smithkline Beecham Corporation 7-keto or hydroxy 3,5-diene steroids as inhibitors of steroid 5-alpha reductase
US5091380A (en) * 1990-06-28 1992-02-25 Merck & Co., Inc. N-monosubstituted adamantyl/norbornanyl 17β-carbamides of 3-carboxy-androst-3,5-dienes as testosterone 5α-reductase inhibitors

Also Published As

Publication number Publication date
IL104601A0 (en) 1993-07-08
SI9300067A (en) 1993-09-30
CN1078474A (zh) 1993-11-17
MA22787A1 (fr) 1993-10-01
EP0626972A4 (en) 1995-01-04
KR950700320A (ko) 1995-01-16
CA2129347A1 (en) 1993-08-19
AU3612893A (en) 1993-09-03
MX9300677A (es) 1994-07-29
WO1993016098A1 (en) 1993-08-19
JPH07505618A (ja) 1995-06-22
EP0626972A1 (en) 1994-12-07
TW241266B (zh) 1995-02-21

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