JPH07504203A - 腫瘍壊死因子アンタゴニストを用いるtnf−依存性炎症の治療方法 - Google Patents

腫瘍壊死因子アンタゴニストを用いるtnf−依存性炎症の治療方法

Info

Publication number
JPH07504203A
JPH07504203A JP6508252A JP50825294A JPH07504203A JP H07504203 A JPH07504203 A JP H07504203A JP 6508252 A JP6508252 A JP 6508252A JP 50825294 A JP50825294 A JP 50825294A JP H07504203 A JPH07504203 A JP H07504203A
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JP
Japan
Prior art keywords
tnfr
tnf
sequence
soluble
cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6508252A
Other languages
English (en)
Japanese (ja)
Inventor
スミス,クレイグ・エイ
ヤコブス,シンディー・エイ
Original Assignee
イミュネックス・コーポレーション
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25484181&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH07504203(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by イミュネックス・コーポレーション filed Critical イミュネックス・コーポレーション
Publication of JPH07504203A publication Critical patent/JPH07504203A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Pain & Pain Management (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
JP6508252A 1992-09-15 1993-09-14 腫瘍壊死因子アンタゴニストを用いるtnf−依存性炎症の治療方法 Pending JPH07504203A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US946,236 1978-09-27
US94623692A 1992-09-15 1992-09-15
PCT/US1993/008666 WO1994006476A1 (en) 1992-09-15 1993-09-14 Method of treating tnf-dependent inflammation using tumor necrosis factor antagonists

Publications (1)

Publication Number Publication Date
JPH07504203A true JPH07504203A (ja) 1995-05-11

Family

ID=25484181

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6508252A Pending JPH07504203A (ja) 1992-09-15 1993-09-14 腫瘍壊死因子アンタゴニストを用いるtnf−依存性炎症の治療方法

Country Status (8)

Country Link
EP (1) EP0620739A4 (no)
JP (1) JPH07504203A (no)
KR (1) KR100232688B1 (no)
AU (1) AU670125B2 (no)
CA (1) CA2123593C (no)
NO (1) NO941780L (no)
NZ (1) NZ256293A (no)
WO (1) WO1994006476A1 (no)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002534375A (ja) * 1998-12-30 2002-10-15 アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ 活性阻害
JP2003501043A (ja) * 1999-05-28 2003-01-14 ターゲティッド ジェネティクス コーポレイション 腫瘍壊死因子(tnf)関連障害において、tnfのレベルを低下させるための方法および組成物
JP2006500927A (ja) * 2002-09-13 2006-01-12 ザ・ユニバーシティ・オブ・クイーンズランド コドン翻訳効率に基づく遺伝子発現系
JP2006512900A (ja) * 2002-08-16 2006-04-20 ワイス Rage関連疾患の治療用組成物及び方法
JP2007084558A (ja) * 1998-10-23 2007-04-05 Amgen 治療薬としての修飾ペプチド
US7229962B2 (en) 2001-07-26 2007-06-12 Medexgen Co., Ltd. Tetravalent etanercept
JPWO2005035586A1 (ja) * 2003-10-08 2007-11-22 協和醗酵工業株式会社 融合蛋白質組成物
JP2010501622A (ja) * 2006-08-28 2010-01-21 アレス トレーディング ソシエテ アノニム Fc−融合タンパク質の精製法

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JP2007084558A (ja) * 1998-10-23 2007-04-05 Amgen 治療薬としての修飾ペプチド
JP2002534375A (ja) * 1998-12-30 2002-10-15 アプライド・リサーチ・システムズ・エイアールエス・ホールディング・ナムローゼ・フェンノートシャップ 活性阻害
JP2003501043A (ja) * 1999-05-28 2003-01-14 ターゲティッド ジェネティクス コーポレイション 腫瘍壊死因子(tnf)関連障害において、tnfのレベルを低下させるための方法および組成物
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US7670602B2 (en) 2001-07-26 2010-03-02 Medexgen Co., Ltd Concatameric immunoadhesion molecule
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EP0620739A4 (en) 1997-01-15
NZ256293A (en) 1997-06-24
KR100232688B1 (ko) 1999-12-01
CA2123593A1 (en) 1994-03-31
NO941780L (no) 1994-07-15
CA2123593C (en) 2000-03-14
EP0620739A1 (en) 1994-10-26
AU670125B2 (en) 1996-07-04

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