JPH07102148B2 - 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物 - Google Patents

遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物

Info

Publication number
JPH07102148B2
JPH07102148B2 JP4127673A JP12767392A JPH07102148B2 JP H07102148 B2 JPH07102148 B2 JP H07102148B2 JP 4127673 A JP4127673 A JP 4127673A JP 12767392 A JP12767392 A JP 12767392A JP H07102148 B2 JPH07102148 B2 JP H07102148B2
Authority
JP
Japan
Prior art keywords
human serum
serum albumin
salt concentration
hsa
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP4127673A
Other languages
English (en)
Japanese (ja)
Other versions
JPH05317079A (ja
Inventor
孝男 大村
昭典 鷲見
渡 大谷
直人 古畑
一哉 竹島
佳永子 上出
宗宏 野田
雅英 近藤
昭一 石川
和宏 大原
和正 横山
Original Assignee
株式会社ミドリ十字
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 株式会社ミドリ十字 filed Critical 株式会社ミドリ十字
Priority to JP4127673A priority Critical patent/JPH07102148B2/ja
Priority to US08/036,387 priority patent/US5440018A/en
Priority to TW82103548A priority patent/TW275633B/zh
Priority to EP01100133A priority patent/EP1099708A1/en
Priority to DE69331507T priority patent/DE69331507T2/de
Priority to ES93108099T priority patent/ES2170060T3/es
Priority to DK93108099T priority patent/DK0570916T3/da
Priority to EP93108099A priority patent/EP0570916B1/en
Priority to CA002096572A priority patent/CA2096572A1/en
Priority to KR1019930008523A priority patent/KR100386762B1/ko
Priority to KR1019930008523A priority patent/KR940005800A/ko
Publication of JPH05317079A publication Critical patent/JPH05317079A/ja
Priority to US08/202,130 priority patent/US5521287A/en
Priority to US08/538,471 priority patent/US5986062A/en
Publication of JPH07102148B2 publication Critical patent/JPH07102148B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Landscapes

  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
JP4127673A 1992-05-20 1992-05-20 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物 Expired - Lifetime JPH07102148B2 (ja)

Priority Applications (13)

Application Number Priority Date Filing Date Title
JP4127673A JPH07102148B2 (ja) 1992-05-20 1992-05-20 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
US08/036,387 US5440018A (en) 1992-05-20 1993-03-24 Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
TW82103548A TW275633B (enrdf_load_stackoverflow) 1992-05-20 1993-05-06
EP93108099A EP0570916B1 (en) 1992-05-20 1993-05-18 Process for the purification of human recombinant serum albumin
DE69331507T DE69331507T2 (de) 1992-05-20 1993-05-18 Verfahren zur Reinigung von menschlichem, rekombinantem Serumalbumin
ES93108099T ES2170060T3 (es) 1992-05-20 1993-05-18 Procedimiento para la preparacion de albumina serica humana recombinante.
DK93108099T DK0570916T3 (da) 1992-05-20 1993-05-18 Fremgangsmåde til rensning af humant rekombinant serumalbumin
EP01100133A EP1099708A1 (en) 1992-05-20 1993-05-18 Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
KR1019930008523A KR940005800A (ko) 1992-05-20 1993-05-19 재조합 사람 혈청 알부민, 이의 제조 방법 및 이를 함유하는 약제
KR1019930008523A KR100386762B1 (ko) 1992-05-20 1993-05-19 재조합사람혈청알부민의제조방법
CA002096572A CA2096572A1 (en) 1992-05-20 1993-05-19 Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US08/202,130 US5521287A (en) 1992-05-20 1994-02-25 Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US08/538,471 US5986062A (en) 1992-05-20 1995-10-03 Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP4127673A JPH07102148B2 (ja) 1992-05-20 1992-05-20 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP9000440A Division JP2885212B2 (ja) 1997-01-06 1997-01-06 遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物

Publications (2)

Publication Number Publication Date
JPH05317079A JPH05317079A (ja) 1993-12-03
JPH07102148B2 true JPH07102148B2 (ja) 1995-11-08

Family

ID=14965889

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4127673A Expired - Lifetime JPH07102148B2 (ja) 1992-05-20 1992-05-20 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物

Country Status (2)

Country Link
JP (1) JPH07102148B2 (enrdf_load_stackoverflow)
TW (1) TW275633B (enrdf_load_stackoverflow)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH07308199A (ja) 1994-05-18 1995-11-28 Green Cross Corp:The ヒト血清アルブミンの製造方法
JP2885212B2 (ja) * 1997-01-06 1999-04-19 吉富製薬株式会社 遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物
GB9902000D0 (en) * 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process
JP4798832B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の除去方法
JP4798830B2 (ja) * 2000-10-24 2011-10-19 一般財団法人化学及血清療法研究所 ヒト血清アルブミン多量体の単量体化方法
JP2002265383A (ja) * 2001-03-14 2002-09-18 Mitsubishi Pharma Corp インターフェロンα注射用液状製剤
DE60333821D1 (de) * 2002-02-28 2010-09-30 Nipro Corp Stabilisierte albumin-zubereitungen
SE526227C2 (sv) * 2002-05-15 2005-08-02 North China Pharmaceutical Group Metod för rening av rekombinant humant serumalbumin
DE602005013912D1 (de) * 2004-01-20 2009-05-28 Chemo Sero Therapeut Res Inst Verfahren zur herstellung von humanserumalbumin durch wärmebehandlung in gegenwart von zweiwertigem kation
US7307148B2 (en) * 2004-04-23 2007-12-11 Conjuchem Biotechnologies Inc. Method for purification of albumin conjugates
CN102127164B (zh) * 2010-12-20 2013-01-30 武汉禾元生物科技有限公司 一种从水稻种子中提取重组人血清白蛋白的方法
CN102532254B (zh) * 2010-12-24 2015-06-24 武汉禾元生物科技股份有限公司 一种从水稻种子中分离纯化重组人血清白蛋白的方法
CN112210002B (zh) * 2020-10-15 2022-06-10 楚天源创生物技术(长沙)有限公司 重组人血清白蛋白的纯化方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL66614A (en) * 1981-08-28 1985-09-29 Genentech Inc Method of constructing a dna sequence encoding a polypeptide,microbial production of human serum albumin,and pharmaceutical compositions comprising it
JP3554796B2 (ja) * 1988-10-31 2004-08-18 三菱ウェルファーマ株式会社 アルブミン製剤及びその製造方法
CA2022165C (en) * 1989-10-05 1999-11-23 Chong E. Chang Albumin purification
EP0452753B1 (en) * 1990-04-19 2004-06-23 Bayer Corporation Method for preparing essentially monomeric normal serum albumin (human)
JP3230091B2 (ja) * 1990-06-25 2001-11-19 ウェルファイド株式会社 ヒト血清アルブミンの着色抑制方法

Also Published As

Publication number Publication date
TW275633B (enrdf_load_stackoverflow) 1996-05-11
JPH05317079A (ja) 1993-12-03

Similar Documents

Publication Publication Date Title
EP0570916B1 (en) Process for the purification of human recombinant serum albumin
US5986062A (en) Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
US5132404A (en) Method of purifying human serum albumin using organic carboxylic acids and acetyl tryptophan
AU783638B2 (en) Method of producing human serum albumin involving heating step
JPH07102148B2 (ja) 遺伝子操作により得られるヒト血清アルブミンの製造方法、およびそれにより得られるヒト血清アルブミン含有組成物
JP3360315B2 (ja) ヒト血清アルブミンの高度精製方法
AU783871B2 (en) Method of eliminating human serum albumin polymers
JPH07308199A (ja) ヒト血清アルブミンの製造方法
JPH05260986A (ja) ヒト血清アルブミンの着色抑制方法
EP0612761A1 (en) Human serum albumin and process for producing the same
JP2885212B2 (ja) 遺伝子操作由来のヒト血清アルブミンより得られる高純度ヒト血清アルブミン含有組成物
JP3840674B2 (ja) 遺伝子操作に由来するヒト血清アルブミンの精製方法
EP0658569B1 (en) Method for decoloring human serum albumin
JP2869417B2 (ja) 遺伝子操作により得られるヒト血清アルブミン
JP3508149B2 (ja) ヒト血清アルブミンおよびその製造方法
JPH0672891A (ja) ヒト血清アルブミン含有製剤
JP4016999B2 (ja) 遺伝子操作に由来するヒト血清アルブミンの精製方法
JP2004002449A (ja) ヒト血清アルブミンおよびその製造方法
JPH11191A (ja) 遺伝子操作により得られるヒト血清アルブミン
JP2004002450A (ja) ヒト血清アルブミン
JPH06245788A (ja) ヒト血清アルブミンおよびその製造方法
JPH07170993A (ja) ヒト血清アルブミンの脱色方法
JPH05328991A (ja) ヒト血清アルブミンの脱色方法
JPH07170994A (ja) ヒト血清アルブミンの脱色方法
JP2007130025A (ja) 遺伝子操作に由来するヒト血清アルブミンの精製方法

Legal Events

Date Code Title Description
R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

R250 Receipt of annual fees

Free format text: JAPANESE INTERMEDIATE CODE: R250

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20071108

Year of fee payment: 12

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20081108

Year of fee payment: 13

S111 Request for change of ownership or part of ownership

Free format text: JAPANESE INTERMEDIATE CODE: R313111

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20081108

Year of fee payment: 13

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20081108

Year of fee payment: 13

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20091108

Year of fee payment: 14

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101108

Year of fee payment: 15

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101108

Year of fee payment: 15

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101108

Year of fee payment: 15

R371 Transfer withdrawn

Free format text: JAPANESE INTERMEDIATE CODE: R371

S531 Written request for registration of change of domicile

Free format text: JAPANESE INTERMEDIATE CODE: R313531

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101108

Year of fee payment: 15

R350 Written notification of registration of transfer

Free format text: JAPANESE INTERMEDIATE CODE: R350

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20101108

Year of fee payment: 15

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20111108

Year of fee payment: 16

FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121108

Year of fee payment: 17

EXPY Cancellation because of completion of term
FPAY Renewal fee payment (event date is renewal date of database)

Free format text: PAYMENT UNTIL: 20121108

Year of fee payment: 17