JPH0649649B2 - 腎臓障害の阻止治療薬 - Google Patents

腎臓障害の阻止治療薬

Info

Publication number
JPH0649649B2
JPH0649649B2 JP60503369A JP50336985A JPH0649649B2 JP H0649649 B2 JPH0649649 B2 JP H0649649B2 JP 60503369 A JP60503369 A JP 60503369A JP 50336985 A JP50336985 A JP 50336985A JP H0649649 B2 JPH0649649 B2 JP H0649649B2
Authority
JP
Japan
Prior art keywords
iloprost
ccl
medium
cells
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60503369A
Other languages
English (en)
Japanese (ja)
Other versions
JPS61502819A (ja
Inventor
アドラー,ギド
シユルテ‐ヘルマン,ロルフ
ローゲ,オラフ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS61502819A publication Critical patent/JPS61502819A/ja
Publication of JPH0649649B2 publication Critical patent/JPH0649649B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/557Eicosanoids, e.g. leukotrienes or prostaglandins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
JP60503369A 1984-07-25 1985-07-18 腎臓障害の阻止治療薬 Expired - Lifetime JPH0649649B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19843427797 DE3427797A1 (de) 1984-07-25 1984-07-25 Zytoprotektive wirkung von prostacyclin-derivaten an leber, bauchspeicheldruese und niere
DE3427797.8 1984-07-25
PCT/DE1985/000245 WO1986000808A1 (en) 1984-07-25 1985-07-18 Prostacycline derivatives with a cytoprotective action on the liver, the pancreas and the kidney

Publications (2)

Publication Number Publication Date
JPS61502819A JPS61502819A (ja) 1986-12-04
JPH0649649B2 true JPH0649649B2 (ja) 1994-06-29

Family

ID=6241773

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60503369A Expired - Lifetime JPH0649649B2 (ja) 1984-07-25 1985-07-18 腎臓障害の阻止治療薬

Country Status (5)

Country Link
US (1) US5049582A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0191792B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPH0649649B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (3) DE3427797A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
WO (1) WO1986000808A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3631169A1 (de) * 1986-09-11 1988-03-24 Schering Ag Prostacyclinderivate enthaltende mittel fuer die topische anwendung
DE3740838A1 (de) * 1987-11-27 1989-06-08 Schering Ag Cyclodextrinclathrate von 5-cyano-prostacyclinderivaten und ihre verwendung als arzneimittel
KR0154101B1 (ko) * 1988-12-23 1998-11-16 이다가끼 히로시 이소카르바사이클린류를함유하는간장해의예방또는치료용조성물
US5364883A (en) * 1988-12-23 1994-11-15 Teijin Limited Isocarbocyclins for the treatment of liver and kidney diseases
JPH089544B2 (ja) * 1989-08-09 1996-01-31 株式会社上野製薬応用研究所 腸内排泄剤
DE4135193C1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * 1991-10-22 1993-03-11 Schering Ag Berlin Und Bergkamen, 1000 Berlin, De
CA2099667C (en) * 1991-10-25 1999-04-13 Shinya Ueno Agent for treating hepatic diseases
WO1994026103A1 (fr) * 1993-05-07 1994-11-24 Chugai Seiyaku Kabushiki Kaisha Agent de conservation d'organe
DE10253623B4 (de) * 2002-11-15 2006-03-09 Justus-Liebig-Universität Giessen Bioabbaubare kolloidale Partikel, insbesondere für pulmonale Applikationen
CN102697790A (zh) * 2003-05-22 2012-10-03 联合治疗公司 化合物和释放前列环素类似物的方法
JP2009543826A (ja) * 2006-07-18 2009-12-10 バイエル・シエーリング・ファーマ アクチエンゲゼルシャフト 自己免疫疾患治療剤としての5−シアノ−プロスタサイクリン誘導体
WO2008058766A1 (en) 2006-11-16 2008-05-22 Bayer Schering Pharma Aktiengesellschaft Ep2 and ep4 agonists as agents for the treatment of influenza a viral infection
US7776896B2 (en) 2007-03-28 2010-08-17 Bayer Schering Pharma Aktiengesellschaft 5-cyano-prostacyclin derivatives as agents for the treatment of influenza a viral infection
JP2016517410A (ja) 2013-03-14 2016-06-16 ユナイテッド セラピューティクス コーポレイション トレプロスチニルの固体形態

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011591A1 (de) * 1978-10-19 1980-05-28 Schering Aktiengesellschaft Neue Prostanderivate, ihre Herstellung und sie enthaltende Arzneimittel
JPS58164512A (ja) * 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS58203911A (ja) * 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2753244A1 (de) * 1977-11-25 1979-06-07 Schering Ag Neue prostacyclinderivate und verfahren zu ihrer herstellung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0011591A1 (de) * 1978-10-19 1980-05-28 Schering Aktiengesellschaft Neue Prostanderivate, ihre Herstellung und sie enthaltende Arzneimittel
JPS58164512A (ja) * 1982-03-25 1983-09-29 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する肝臓疾患治療剤
JPS58203911A (ja) * 1982-05-25 1983-11-28 Ono Pharmaceut Co Ltd プロスタグランジン類似化合物を有効成分として含有する細肪障害治療剤

Also Published As

Publication number Publication date
DE3585282D1 (de) 1992-03-05
DE3427797A1 (de) 1986-02-06
DE3448257C2 (en) 1988-08-18
EP0191792B1 (de) 1992-01-22
US5049582A (en) 1991-09-17
JPS61502819A (ja) 1986-12-04
DE3427797C2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1988-08-11
EP0191792A1 (de) 1986-08-27
WO1986000808A1 (en) 1986-02-13

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