JPH0569507B2 - - Google Patents
Info
- Publication number
- JPH0569507B2 JPH0569507B2 JP59035894A JP3589484A JPH0569507B2 JP H0569507 B2 JPH0569507 B2 JP H0569507B2 JP 59035894 A JP59035894 A JP 59035894A JP 3589484 A JP3589484 A JP 3589484A JP H0569507 B2 JPH0569507 B2 JP H0569507B2
- Authority
- JP
- Japan
- Prior art keywords
- plasminogen activator
- lysine
- tissue
- present
- solution
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Landscapes
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59035894A JPS60181028A (ja) | 1984-02-29 | 1984-02-29 | 組織プラスミノ−ゲン・アクチベ−タ−の溶解補助法 |
EP85102058A EP0156169B1 (en) | 1984-02-29 | 1985-02-25 | An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method |
DE8585102058T DE3584902D1 (de) | 1984-02-29 | 1985-02-25 | Waessrige loesung eines darin in erhoehter konzentration aufgeloesten gewebe-plasminogen-aktivators und herstellungsverfahren. |
US06/705,896 US4568544A (en) | 1984-02-29 | 1985-02-26 | Aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP59035894A JPS60181028A (ja) | 1984-02-29 | 1984-02-29 | 組織プラスミノ−ゲン・アクチベ−タ−の溶解補助法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS60181028A JPS60181028A (ja) | 1985-09-14 |
JPH0569507B2 true JPH0569507B2 (enrdf_load_stackoverflow) | 1993-10-01 |
Family
ID=12454730
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP59035894A Granted JPS60181028A (ja) | 1984-02-29 | 1984-02-29 | 組織プラスミノ−ゲン・アクチベ−タ−の溶解補助法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS60181028A (enrdf_load_stackoverflow) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8513358D0 (en) * | 1985-05-28 | 1985-07-03 | Wellcome Found | Formulation |
JPH0672105B2 (ja) * | 1985-10-02 | 1994-09-14 | 持田製薬株式会社 | 血栓溶解剤及びその製法 |
JPS62120321A (ja) * | 1985-11-20 | 1987-06-01 | Eisai Co Ltd | tPA含有医薬組成物 |
DE3718889A1 (de) * | 1987-06-05 | 1988-12-22 | Behringwerke Ag | Verfahren zur herstellung einer loesung hoher spezifischer volumenaktivitaet von einem protein mit gewebe-plasminogenaktivator (t-pa)-aktivitaet, loesung, enthaltend protein mit t-pa-aktivitaet und verwendung der loesung in der human- und veterinaermedizin |
JP2708749B2 (ja) * | 1987-08-10 | 1998-02-04 | エーザイ株式会社 | 修飾型tPA含有注射用組成物 |
JP2520975B2 (ja) * | 1989-09-21 | 1996-07-31 | 三井東圧化学株式会社 | 組織プラスミノ―ゲンアクチベ―タ―若しくはその誘導体を含有する血栓溶解剤 |
-
1984
- 1984-02-29 JP JP59035894A patent/JPS60181028A/ja active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS60181028A (ja) | 1985-09-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EP0100982B1 (en) | Novel purified plasminogen activator, process for its production and thrombolytic composition containing it | |
EP0156169B1 (en) | An aqueous solution of a tissue plasminogen activator dissolved therein at an increased concentration and a method | |
CA1206434A (en) | Method for stabilizing tissue plasminogen activator and a stable aqueous solution or powder containing the same | |
EP0217379B1 (en) | Thrombolytic composition and a process for production thereof | |
JPH05227962A (ja) | ウイルス安全性精製ヒトトロンビン | |
JP2010540432A (ja) | ヒト組織型プラスミノーゲンアクチベータの精製方法 | |
US4020268A (en) | Agarose containing affinity matrix materials | |
SE406913B (sv) | Forfarande for rening eller lagning av ett enzym genom kontakt med affinitelsmatrismaterial | |
JPH0569507B2 (enrdf_load_stackoverflow) | ||
JPS60184026A (ja) | 組織プラスミノ−ゲン・アクチベ−タ−の溶解補助方法 | |
US4550080A (en) | Process for the preparation of a plasminogen activator | |
EP0151996B1 (en) | Process for the preparation of a double-chain plasminogen activator | |
JPS6360938A (ja) | 修飾組織型プラスミノ−ゲン活性化因子およびその製造方法 | |
EP0163751A1 (en) | Process for the preparation of a plasminogen activator | |
JPS60248621A (ja) | 一本鎖組織プラスミノ−ゲンアクチベ−タ−の安定化方法 | |
JP2861655B2 (ja) | ヒト尿性トリプシンインヒビター含有液状製剤及びその製造方法 | |
JPS60174727A (ja) | 新規なプラスミノ−ゲン・アクチベ−タ−の安定化方法 | |
CA1206903A (en) | Process for the preparation of a plasminogen activator | |
JPH0521551B2 (enrdf_load_stackoverflow) | ||
JPS62283932A (ja) | 組織プラスミノ−ゲンアクチベ−タの乾燥製剤 | |
JPH0558910A (ja) | トリプシンインヒビター含有凍結乾燥製剤 | |
JPS63174934A (ja) | ウロキナ−ゼ前駆体乾燥製剤 | |
JP2714817B2 (ja) | ウロキナーゼ前駆体の製造方法 | |
JPS60158116A (ja) | 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤 | |
JPH0329390B2 (enrdf_load_stackoverflow) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EXPY | Cancellation because of completion of term |