JPH0513958B2 - - Google Patents
Info
- Publication number
- JPH0513958B2 JPH0513958B2 JP63292551A JP29255188A JPH0513958B2 JP H0513958 B2 JPH0513958 B2 JP H0513958B2 JP 63292551 A JP63292551 A JP 63292551A JP 29255188 A JP29255188 A JP 29255188A JP H0513958 B2 JPH0513958 B2 JP H0513958B2
- Authority
- JP
- Japan
- Prior art keywords
- naphtholphthalein
- monophosphate
- general formula
- formula
- alkaline phosphatase
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/42—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving phosphatase
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
- C07F9/65517—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring condensed with carbocyclic rings or carbocyclic ring systems
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2334/00—O-linked chromogens for determinations of hydrolase enzymes, e.g. glycosidases, phosphatases, esterases
- C12Q2334/40—Triphenylmethane dye chromogens, e.g. fluorescein derivatives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19873739284 DE3739284A1 (de) | 1987-11-20 | 1987-11-20 | 1-naphtholphthaleinmonophosphate, verfahren zu deren herstellung sowie deren verwendung zur bestimmung der alkalischen phosphatase |
| DE3739284.0 | 1987-11-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01160990A JPH01160990A (ja) | 1989-06-23 |
| JPH0513958B2 true JPH0513958B2 (enExample) | 1993-02-23 |
Family
ID=6340842
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP63292551A Granted JPH01160990A (ja) | 1987-11-20 | 1988-11-21 | １−ナフトールフタレインモノホスフエート、その製法、アルカリホスフアターゼの測定法及びアルカリホスフアターゼ検出用診断剤 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4985414A (enExample) |
| EP (1) | EP0316791B1 (enExample) |
| JP (1) | JPH01160990A (enExample) |
| AT (1) | ATE86626T1 (enExample) |
| DE (2) | DE3739284A1 (enExample) |
| ES (1) | ES2054771T3 (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2646814B2 (ja) * | 1990-08-07 | 1997-08-27 | アイシン精機株式会社 | 核酸等の検定方法 |
| DE19632432A1 (de) * | 1996-08-12 | 1998-02-19 | Boehringer Mannheim Gmbh | Stabile Mischung zum Nachweis alkalischer Phosphatase mit einem Salz der o-Kresolphthaleinmonophosphorsäure |
| BR102013023221B1 (pt) * | 2013-09-11 | 2021-08-17 | Universidade Federal Do Rio De Janeiro | Processo de síntese de fenolftaleína bisfosfato tetrassódio e kit |
| CN119935989A (zh) * | 2024-12-19 | 2025-05-06 | 卡秋(江苏)生物科技有限公司 | 一种适用于全自动免疫组化染色液的碱性磷酸酶显色液 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3331862A (en) * | 1964-06-05 | 1967-07-18 | Warner Lambert Pharmaceutical | Phenolphthalein-mono-phosphate derivatives |
| US3331857A (en) * | 1964-10-01 | 1967-07-18 | Warner Lambert Pharmaceutical | Phenolphthalein monophosphate derivatives |
| US3823071A (en) * | 1970-12-21 | 1974-07-09 | Worthington Biochem Corp | Prostatic acid phosphatase determination |
| US3931228A (en) * | 1971-01-21 | 1976-01-06 | Polaroid Corporation | Process for preparing phthalide and naphthalide indicator dyes |
| US4035391A (en) * | 1974-02-28 | 1977-07-12 | Polaroid Corporation | Phthalide and naphthalide derivatives |
| US3975405A (en) * | 1974-08-01 | 1976-08-17 | Coulter Diagnostics, Inc. | Monophosphate salt of o-cresolphthalein |
| US4032545A (en) * | 1975-09-29 | 1977-06-28 | Polaroid Corporation | Phthalides and naphthalides |
-
1987
- 1987-11-20 DE DE19873739284 patent/DE3739284A1/de not_active Withdrawn
-
1988
- 1988-11-11 EP EP88118800A patent/EP0316791B1/de not_active Expired - Lifetime
- 1988-11-11 DE DE8888118800T patent/DE3879107D1/de not_active Expired - Fee Related
- 1988-11-11 AT AT88118800T patent/ATE86626T1/de not_active IP Right Cessation
- 1988-11-11 ES ES88118800T patent/ES2054771T3/es not_active Expired - Lifetime
- 1988-11-18 US US07/273,403 patent/US4985414A/en not_active Expired - Fee Related
- 1988-11-21 JP JP63292551A patent/JPH01160990A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0316791B1 (de) | 1993-03-10 |
| ATE86626T1 (de) | 1993-03-15 |
| DE3739284A1 (de) | 1989-06-01 |
| DE3879107D1 (de) | 1993-04-15 |
| US4985414A (en) | 1991-01-15 |
| EP0316791A3 (en) | 1990-06-13 |
| EP0316791A2 (de) | 1989-05-24 |
| ES2054771T3 (es) | 1994-08-16 |
| JPH01160990A (ja) | 1989-06-23 |
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