JPH0437806B2 - - Google Patents
Info
- Publication number
- JPH0437806B2 JPH0437806B2 JP58122945A JP12294583A JPH0437806B2 JP H0437806 B2 JPH0437806 B2 JP H0437806B2 JP 58122945 A JP58122945 A JP 58122945A JP 12294583 A JP12294583 A JP 12294583A JP H0437806 B2 JPH0437806 B2 JP H0437806B2
- Authority
- JP
- Japan
- Prior art keywords
- hbsag
- gel
- freeze
- aluminum
- hepatitis
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Mycology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58122945A JPS6013718A (ja) | 1983-07-05 | 1983-07-05 | B型肝炎ワクチン |
AU29993/84A AU572162B2 (en) | 1983-07-05 | 1984-06-28 | Hepatitis b vaccine |
KR1019840003814A KR910005888B1 (ko) | 1983-07-05 | 1984-07-02 | 동결건조 b형 간염 왁진의 제조방법 |
AT84107773T ATE41309T1 (de) | 1983-07-05 | 1984-07-04 | Hepatitis-b-vakzin und verfahren zur herstellung. |
DE8484107773T DE3477139D1 (en) | 1983-07-05 | 1984-07-04 | Hepatitis b vaccine and method for its preparation |
EP84107773A EP0130619B1 (en) | 1983-07-05 | 1984-07-04 | Hepatitis b vaccine and method for its preparation |
CA000458226A CA1237076A (en) | 1983-07-05 | 1984-07-05 | Hepatitis b vaccine |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP58122945A JPS6013718A (ja) | 1983-07-05 | 1983-07-05 | B型肝炎ワクチン |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6013718A JPS6013718A (ja) | 1985-01-24 |
JPH0437806B2 true JPH0437806B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1992-06-22 |
Family
ID=14848502
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP58122945A Granted JPS6013718A (ja) | 1983-07-05 | 1983-07-05 | B型肝炎ワクチン |
Country Status (7)
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS60193925A (ja) * | 1984-03-13 | 1985-10-02 | Chemo Sero Therapeut Res Inst | 凍結乾燥製剤化ワクチン |
EP0294071A3 (en) * | 1987-06-03 | 1990-08-01 | Merck & Co. Inc. | Hepatitis b vaccines made with pre-formed aluminum hydroxide gels, and processes thereof |
CZ283910B6 (cs) * | 1992-05-23 | 1998-07-15 | Smithkline Beecham Biologicals (S.A.) | Kombinovaný očkovací prostředek, způsob jeho výroby a použití fosforečnanu hlinitého jako pomocného prostředku |
WO1994007469A1 (en) * | 1992-09-25 | 1994-04-14 | Dynagen, Inc. | An immunobooster for delayed release of immunogen |
US6051238A (en) * | 1996-12-20 | 2000-04-18 | Merck & Co., Inc. | Stabilizers for lyophilized mumps vaccines |
US6290967B1 (en) * | 1996-12-20 | 2001-09-18 | Merck & Co., Inc. | Stabilizers for lyophilized vaccines |
WO2001093829A2 (en) * | 2000-06-08 | 2001-12-13 | Powderject Vaccines, Inc. | Powder compositions |
UA79735C2 (uk) | 2000-08-10 | 2007-07-25 | Глаксосмітклайн Байолоджікалз С.А. | Очищення антигенів вірусу гепатиту b (hbv) для використання у вакцинах |
JP2004532277A (ja) | 2001-06-08 | 2004-10-21 | パウダージェクト ワクチンズ,インコーポレーテッド | 噴霧凍結乾燥組成物 |
KR20030025480A (ko) * | 2001-09-21 | 2003-03-29 | 보령제약 주식회사 | 약독화 수두 생바이러스 백신용 무단백질 안정화제 |
US20060228369A1 (en) * | 2005-04-11 | 2006-10-12 | Program For Appropriate Technology In Health | Stabilization and preservation of temperature-sensitive vaccines |
US20090155351A1 (en) | 2005-10-04 | 2009-06-18 | Alk-Abello A/S | Solid Vaccine Formulation |
AU2007317847B2 (en) | 2006-11-07 | 2013-10-31 | Sanofi Pasteur Biologics, Llc | Stabilization of vaccines by lyophilization |
TW201043267A (en) * | 2009-03-19 | 2010-12-16 | Intervet Int Bv | In situ constituting a vaccine for administration to a predetermined herd of animals |
BR112012025047A2 (pt) | 2010-03-31 | 2016-06-21 | Stabilitech Ltd | formulações líquidas estabilizadas |
HUE042330T2 (hu) * | 2010-03-31 | 2019-06-28 | Stabilitech Biopharma Ltd | Módszer alumínium adjuvánsok és alumíniummal adjuvált vakcinák megóvására |
DK2552465T3 (en) | 2010-03-31 | 2015-07-27 | Stabilitech Ltd | Stabilization of virus particles |
AU2012272788B2 (en) | 2011-06-24 | 2016-10-20 | Merck Sharp & Dohme Llc | HPV vaccine formulations comprising aluminum adjuvant and methods of producing same |
US9574005B2 (en) | 2011-07-19 | 2017-02-21 | Chugai Seiyaku Kabushiki Kaisha | Stable Protein-containing preparation containing argininamide or analogous compound thereof |
GB201117233D0 (en) | 2011-10-05 | 2011-11-16 | Stabilitech Ltd | Stabilisation of polypeptides |
JP5931449B2 (ja) * | 2012-01-11 | 2016-06-08 | 日東電工株式会社 | 医薬組成物及びその製造方法 |
GB201406569D0 (en) | 2014-04-11 | 2014-05-28 | Stabilitech Ltd | Vaccine compositions |
EP3444004B1 (en) * | 2016-04-15 | 2020-12-02 | FUJIFILM Corporation | Microneedle array |
GB2562241B (en) | 2017-05-08 | 2022-04-06 | Stabilitech Biopharma Ltd | Vaccine compositions |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2879202A (en) * | 1954-11-05 | 1959-03-24 | American Cyanamid Co | Stabilization of live viral vaccines by hexahydric alcohols |
DE1617457A1 (de) * | 1966-12-16 | 1972-04-20 | Erba Carlo Spa | Verfahren zur Stabilisierung von Zubereitungen interferierender Virusprodukte |
DE1617350C3 (de) * | 1967-06-22 | 1979-09-06 | Behringwerke Ag, 3550 Marburg | Verfahren zur Inaktivierung von biologischem Material |
US3636191A (en) * | 1969-10-08 | 1972-01-18 | Cancer Res Inst | Vaccine against viral hepatitis and process |
JPS5523253B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-12-28 | 1980-06-21 |
-
1983
- 1983-07-05 JP JP58122945A patent/JPS6013718A/ja active Granted
-
1984
- 1984-06-28 AU AU29993/84A patent/AU572162B2/en not_active Ceased
- 1984-07-02 KR KR1019840003814A patent/KR910005888B1/ko not_active Expired
- 1984-07-04 EP EP84107773A patent/EP0130619B1/en not_active Expired
- 1984-07-04 AT AT84107773T patent/ATE41309T1/de not_active IP Right Cessation
- 1984-07-04 DE DE8484107773T patent/DE3477139D1/de not_active Expired
- 1984-07-05 CA CA000458226A patent/CA1237076A/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ATE41309T1 (de) | 1989-04-15 |
KR910005888B1 (ko) | 1991-08-06 |
EP0130619A2 (en) | 1985-01-09 |
KR850002277A (ko) | 1985-05-10 |
AU572162B2 (en) | 1988-05-05 |
JPS6013718A (ja) | 1985-01-24 |
EP0130619A3 (en) | 1985-04-10 |
EP0130619B1 (en) | 1989-03-15 |
AU2999384A (en) | 1985-01-10 |
DE3477139D1 (en) | 1989-04-20 |
CA1237076A (en) | 1988-05-24 |
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