JPH0430960B2 - - Google Patents

Info

Publication number
JPH0430960B2
JPH0430960B2 JP59122967A JP12296784A JPH0430960B2 JP H0430960 B2 JPH0430960 B2 JP H0430960B2 JP 59122967 A JP59122967 A JP 59122967A JP 12296784 A JP12296784 A JP 12296784A JP H0430960 B2 JPH0430960 B2 JP H0430960B2
Authority
JP
Japan
Prior art keywords
brain
purification
amino acid
manufactured
trade name
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59122967A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6011424A (ja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of JPS6011424A publication Critical patent/JPS6011424A/ja
Publication of JPH0430960B2 publication Critical patent/JPH0430960B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/501—Fibroblast growth factor [FGF] acidic FGF [aFGF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/839—Nerves; brain

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
JP59122967A 1983-06-17 1984-06-16 繊維芽細胞成長因子の精製および特性表示 Granted JPS6011424A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US505553 1983-06-17
US06/505,553 US4444760A (en) 1983-06-17 1983-06-17 Purification and characterization of a protein fibroblast growth factor

Publications (2)

Publication Number Publication Date
JPS6011424A JPS6011424A (ja) 1985-01-21
JPH0430960B2 true JPH0430960B2 (en:Method) 1992-05-25

Family

ID=24010776

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59122967A Granted JPS6011424A (ja) 1983-06-17 1984-06-16 繊維芽細胞成長因子の精製および特性表示

Country Status (7)

Country Link
US (1) US4444760A (en:Method)
EP (1) EP0131150B1 (en:Method)
JP (1) JPS6011424A (en:Method)
CA (1) CA1241639A (en:Method)
CY (1) CY1780A (en:Method)
DE (1) DE3485001D1 (en:Method)
HK (1) HK42694A (en:Method)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5885899A (ja) * 1981-11-16 1983-05-23 Fujirebio Inc アミラ−ゼインヒビタ−およびその製造法
JPS6028999A (ja) * 1983-06-30 1985-02-14 Maruho Kk 細胞増殖促進作用を有するたんぱく質、その組成物と製造方法
US4785079A (en) * 1984-11-09 1988-11-15 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
US5464774A (en) * 1984-03-05 1995-11-07 The Salk Institute For Biological Studies Bovine basic fibroblast growth factor
DE3586355T2 (de) * 1984-11-29 1993-01-14 Univ Minnesota Heilmittel fuer wunden.
US5165938A (en) * 1984-11-29 1992-11-24 Regents Of The University Of Minnesota Wound healing agents derived from platelets
DE3587801T2 (de) * 1984-12-24 1994-10-20 Merck & Co Inc Zubereitung enthaltend ein saures Fibroblastewachstumfaktor (aFGF).
US5401832A (en) * 1984-12-24 1995-03-28 Merck & Co., Inc. Brain derived and recombinant acidic fibroblast growth factor
IE66689B1 (en) * 1985-09-12 1996-01-24 Scios Nova Inc Recombinant fibroblast growth factors
US5439818A (en) * 1985-09-12 1995-08-08 Scios Nova Inc. DNA encoding human recombinant basic fibroblast growth factor
US5859208A (en) * 1988-07-06 1999-01-12 Fiddes; John C. Human basic fibroblast growth factor analog
US5827826A (en) * 1986-03-03 1998-10-27 Rhone-Poulenc Rorer Pharmaceuticals Inc. Compositions of human endothelial cell growth factor
US5552528A (en) 1986-03-03 1996-09-03 Rhone-Poulenc Rorer Pharmaceuticals Inc. Bovine b-endothelial cell growth factor
DE3750197D1 (de) * 1986-04-22 1994-08-18 Salk Inst For Biological Studi Antagonisten des Fibroblasten-Wachstumsfaktors.
CA1294546C (en) * 1986-04-23 1992-01-21 John S. Sundsmo Wound healing composition containing collagen
NZ220917A (en) * 1986-07-11 1991-05-28 Merck & Co Inc Human and bovine acidic fibroblast growth factor vectors, hosts and compositions
US4902782A (en) * 1986-12-10 1990-02-20 The Salk Institute For Biological Studies Isolation of fibroblast growth factor
FR2613936B1 (fr) * 1987-04-17 1990-03-30 Centre Nat Rech Scient Application des resines constituees par des polymeres fonctionnels comme phase stationnaire en chromatographie d'affinite pour la purification des facteurs de croissance et procede de purification correspondant
US5459250A (en) 1987-06-16 1995-10-17 New York University Truncated mammalian growth factor DNA sequence
US5750659A (en) * 1987-06-16 1998-05-12 New York University Mammalian growth factor
JPH03500529A (ja) * 1987-06-18 1991-02-07 モナシュ ユニバーシティ 増殖因子
NZ226170A (en) * 1987-09-18 1990-07-26 Ethicon Inc Stable freeze-dried pharmaceutical composition containing epidermal growth factor
NZ226171A (en) * 1987-09-18 1990-06-26 Ethicon Inc Gel formulation containing polypeptide growth factor
US5312911A (en) * 1987-10-22 1994-05-17 Merck & Co., Inc. Cysteine-modified acidic fibroblast growth factor
AU3863689A (en) * 1988-06-22 1990-01-12 Synergen, Inc. Angiogenic potentiating peptides which potentiate angiogenic factors
CA1341050C (en) * 1988-11-04 2000-07-11 Martin E. Schwab Neurite growth regulatory factors
US5250414A (en) * 1988-11-04 1993-10-05 Erziehungsdirektion Of The Canton Zurich Diagnostic methods using neurite growth regulatory factors
AU652537B2 (en) * 1988-11-04 1994-09-01 Erziehungsdirektion Of The Canton Zurich Neurite growth regulatory factors
DE3900198A1 (de) * 1989-01-05 1990-07-12 Merck Patent Gmbh Topisch anwendbare pharmazeutische zubereitung
US7026291B1 (en) 1989-01-31 2006-04-11 The United States Of America As Represented By The Department Of Health And Human Services Epithelial cell specific growth factor, keratinocyte growth factor (KGF)
AU647732B2 (en) 1989-01-31 1994-03-31 Stuart A. Aaronson DNA encoding a growth factor specific for epithelial cells
JP2814529B2 (ja) * 1989-03-16 1998-10-22 味の素株式会社 虚血性脳障害治療薬
US7300791B2 (en) * 1989-05-12 2007-11-27 Genentech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
US5332671A (en) * 1989-05-12 1994-07-26 Genetech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
US20030114374A1 (en) * 1989-05-12 2003-06-19 Genentech, Inc. Production of vascular endothelial cell growth factor and DNA encoding same
CA2020720A1 (en) * 1989-07-13 1991-01-14 Shigeko Yamazaki Method for the purification of therapeutically active recombinant acidic fibroblast growth factor
US5043431A (en) * 1989-09-11 1991-08-27 Codon Method and apparatus for the production of TGF-β
US5169837A (en) * 1991-03-28 1992-12-08 Allelix Biopharmaceuticals Inc. Isolated osteogenic factor
US5591709A (en) * 1991-08-30 1997-01-07 Life Medical Sciences, Inc. Compositions and methods for treating wounds
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
JPH08501203A (ja) * 1992-06-03 1996-02-13 ケイス・ウエスタン・リザーブ・ユニバーシティー 生理活性物質を連続的に適用するための包帯
US5331095A (en) * 1993-04-12 1994-07-19 Scios Nova Inc. Process for purification of basic fibroblast growth factor
US5800808A (en) * 1994-05-24 1998-09-01 Veda Research And Development Co., Ltd. Copolymer-1 improvements in compositions of copolymers
US5733884A (en) * 1995-11-07 1998-03-31 Nestec Ltd. Enteral formulation designed for optimized wound healing
US20080199513A1 (en) * 1997-06-24 2008-08-21 Cascade Medical Enterprises, Llc Systems and methods for preparing autologous fibrin glue
US7745106B2 (en) * 1997-06-24 2010-06-29 Cascade Medical Enterprises, Llc Methods and devices for separating liquid components
US6979307B2 (en) * 1997-06-24 2005-12-27 Cascade Medical Enterprises Llc Systems and methods for preparing autologous fibrin glue
WO1999066797A1 (en) 1998-06-22 1999-12-29 Worden Charles E Enriched platelet wound healant
US7252818B2 (en) * 1998-07-24 2007-08-07 Cardiovascular Biotherapeutics, Inc. Method of producing biologically active human acidic fibroblast growth factor and its use in promoting angiogenesis
CN100341895C (zh) * 1998-10-08 2007-10-10 张建军 哺乳动物心肌中提取酸性成纤维细胞生长因子样物质的方法
US6897061B1 (en) * 2000-06-16 2005-05-24 Spinal Cord Society Transdifferentiation of glial cells
US7306919B1 (en) 2001-10-31 2007-12-11 Thornthwaite Jerry T Antigen-antibody cancer recognition system
IL162725A0 (en) * 2002-01-14 2005-11-20 Ford Henry Health System Materials from bone marrow stromal cells for use in forming blood vessels and producing angiogenic and trophic factors
EP1890820A4 (en) * 2005-03-22 2012-04-11 Cascade Medical Entpr Llc SYSTEMS AND METHOD FOR PRODUCING MEMBRANES
AU2007292253A1 (en) * 2006-09-08 2008-03-13 Wyeth Arginine wash in protein purification using affinity chromatography
KR101021197B1 (ko) 2008-04-11 2011-03-11 (주)케어젠 성장인자―미미킹 펩타이드 및 그의 용도

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4195017A (en) * 1975-02-25 1980-03-25 Samuel Bogoch Malignin, derived from brain tumor cells, complexes and polypeptides thereof

Also Published As

Publication number Publication date
CA1241639A (en) 1988-09-06
EP0131150A2 (en) 1985-01-16
HK42694A (en) 1994-05-13
JPS6011424A (ja) 1985-01-21
CY1780A (en) 1995-10-20
US4444760A (en) 1984-04-24
DE3485001D1 (de) 1991-10-10
EP0131150A3 (en) 1987-07-15
EP0131150B1 (en) 1991-09-04

Similar Documents

Publication Publication Date Title
JPH0430960B2 (en:Method)
Thomas et al. Purification and characterization of acidic fibroblast growth factor from bovine brain.
Thomas et al. Fibroblast growth factors: broad spectrum mitogens with potent angiogenic activity
EP0128849B1 (en) Purified transforming growth factor-beta derived from human platelets and placentas
Pihlanto-Leppälä et al. Angiotensin I-converting enzyme inhibitory properties of whey protein digests: concentration and characterization of active peptides
JPH0764875B2 (ja) 血液凝固阻害作用を有する新規ポリペプチド
US3948875A (en) Process for the preparation of epidermal growth factor and new derivative using cross-linked polyacrylamide gel at a pH of 1-3
WO2006111060A1 (fr) Procede permettant d’isoler et de purifier un polypeptide immuno-modulant a partir du placenta de vache
WO2011050471A1 (en) Yellow pea seed protein-derived peptides
US4526717A (en) Polypeptide having an action on the immunological system, processes for its isolation and purification, its use, agents containing this compound, and its cleavage products, their use and agents containing these products
PT98695A (pt) Gene codificador do factor neurotrofico de ligacao a heparina
JPS59176238A (ja) ポリペプチド
JP3030312B2 (ja) 成熟肝実質細胞増殖因子（ｉ）
JP2568151B2 (ja) アンジオジェニンの単離方法
CN118108795A (zh) 一种白乌鱼ace抑制肽的制备方法及其应用
EP0085220A2 (en) Method for purification of anterior pituitary hormones
US4552761A (en) Method for influencing the immune systems of mammals using leukorecruitin
JPH1080281A (ja) 新規蛋白質及びその製造方法
CN108586577A (zh) 一种多肽及其应用
JP2632526B2 (ja) 新規ペプチド
US7129334B2 (en) Synthetic peptide and uses for same
EP0939085A1 (en) A process for the purification of a motility-promoting protein from buffalo serum
Cai et al. Isolation from fetal bovine serum of a fragment b of complement factor B-like protein improving a long-term survival of human endothelial cells
JP2802508B2 (ja) 神経栄養ペプチド
CN119978066A (zh) 水牛乳蛋白肽及其制备方法和应用

Legal Events

Date Code Title Description
LAPS Cancellation because of no payment of annual fees