JPH0378393B2 - - Google Patents
Info
- Publication number
- JPH0378393B2 JPH0378393B2 JP57019012A JP1901282A JPH0378393B2 JP H0378393 B2 JPH0378393 B2 JP H0378393B2 JP 57019012 A JP57019012 A JP 57019012A JP 1901282 A JP1901282 A JP 1901282A JP H0378393 B2 JPH0378393 B2 JP H0378393B2
- Authority
- JP
- Japan
- Prior art keywords
- acid addition
- addition salt
- halogen
- general formula
- hydrogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
- 
        - C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
- A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
 
- 
        - A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
 
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title | 
|---|---|---|---|
| HU81324A HU183326B (en) | 1981-02-11 | 1981-02-11 | Process for preparing new apovincaminol-3',4',5'-trimethoxy-benzoates substituted in the a ring and acid addition salts thereof | 
Publications (2)
| Publication Number | Publication Date | 
|---|---|
| JPS57150685A JPS57150685A (en) | 1982-09-17 | 
| JPH0378393B2 true JPH0378393B2 (OSRAM) | 1991-12-13 | 
Family
ID=10949091
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date | 
|---|---|---|---|
| JP57019012A Granted JPS57150685A (en) | 1981-02-11 | 1982-02-10 | A ring-substituted polycyclic compound, manufacture and medicine containing same | 
Country Status (22)
| Country | Link | 
|---|---|
| US (1) | US4432982A (OSRAM) | 
| JP (1) | JPS57150685A (OSRAM) | 
| AR (1) | AR228385A1 (OSRAM) | 
| AT (1) | AT382375B (OSRAM) | 
| AU (1) | AU545745B2 (OSRAM) | 
| BE (1) | BE892070A (OSRAM) | 
| CA (1) | CA1199637A (OSRAM) | 
| DD (1) | DD201593A5 (OSRAM) | 
| DE (1) | DE3204588A1 (OSRAM) | 
| DK (1) | DK151022C (OSRAM) | 
| ES (1) | ES8307803A1 (OSRAM) | 
| FI (1) | FI70019C (OSRAM) | 
| FR (1) | FR2499573B1 (OSRAM) | 
| GB (1) | GB2096597B (OSRAM) | 
| GR (1) | GR75858B (OSRAM) | 
| HU (1) | HU183326B (OSRAM) | 
| IT (1) | IT1157921B (OSRAM) | 
| NL (1) | NL8200493A (OSRAM) | 
| NO (1) | NO820395L (OSRAM) | 
| PT (1) | PT74402B (OSRAM) | 
| SE (1) | SE8200524L (OSRAM) | 
| SU (1) | SU1069626A3 (OSRAM) | 
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| HU192013B (en) * | 1984-04-25 | 1987-04-28 | Richter Gedeon Vegyeszet | Process for production of new aporincavinol esther derivatives | 
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title | 
|---|---|---|---|---|
| FR2035784A1 (en) * | 1969-03-27 | 1970-12-24 | Olivier Louisette | Vincamine derivs with therapeutic propert- - ies | 
| DK139358B (da) * | 1973-12-18 | 1979-02-05 | Sandoz Ag | Analogifremgangsmåde til fremstilling af vincaminderivater eller syreadditionssalte deraf. | 
| US4146643A (en) * | 1973-12-18 | 1979-03-27 | Sandoz Ltd. | Increasing vigilance or treating cerebral insufficiency with substituted vincamines | 
| US4123535A (en) * | 1974-09-06 | 1978-10-31 | Sandoz Ltd. | Psychostimulating 14-amino-14,15-dihydroeburnamenines | 
| HU170888B (hu) * | 1975-06-10 | 1977-09-28 | Richter Gedeon Vegyeszet | Sposob poluchenija novykh, opticheski aktivnykh proizvodnykh eburnameninov | 
| HU177370B (en) * | 1977-07-27 | 1981-09-28 | Richter Gedeon Vegyeszet | Process for producing new bracket-cross-bracket-vincaminol-esters | 
| IL60613A (en) * | 1979-08-16 | 1983-12-30 | Richter Gedeon Vegyeszet | Dermatological compositions applicable directly to the skin comprising an eburnamenine derivative and process for their preparation | 
- 
        1981
        - 1981-02-11 HU HU81324A patent/HU183326B/hu not_active IP Right Cessation
 
- 
        1982
        - 1982-01-26 AT AT0026282A patent/AT382375B/de not_active IP Right Cessation
- 1982-01-29 SE SE8200524A patent/SE8200524L/xx not_active Application Discontinuation
- 1982-02-01 CA CA000395305A patent/CA1199637A/en not_active Expired
- 1982-02-04 FI FI820364A patent/FI70019C/fi not_active IP Right Cessation
- 1982-02-04 US US06/345,633 patent/US4432982A/en not_active Expired - Fee Related
- 1982-02-08 GR GR67243A patent/GR75858B/el unknown
- 1982-02-08 ES ES509418A patent/ES8307803A1/es not_active Expired
- 1982-02-09 FR FR8202046A patent/FR2499573B1/fr not_active Expired
- 1982-02-09 NL NL8200493A patent/NL8200493A/nl not_active Application Discontinuation
- 1982-02-09 PT PT74402A patent/PT74402B/pt unknown
- 1982-02-09 BE BE0/207262A patent/BE892070A/fr not_active IP Right Cessation
- 1982-02-10 DK DK057682A patent/DK151022C/da not_active IP Right Cessation
- 1982-02-10 IT IT19588/82A patent/IT1157921B/it active
- 1982-02-10 DE DE19823204588 patent/DE3204588A1/de active Granted
- 1982-02-10 AU AU80339/82A patent/AU545745B2/en not_active Ceased
- 1982-02-10 DD DD82237317A patent/DD201593A5/de not_active IP Right Cessation
- 1982-02-10 NO NO820395A patent/NO820395L/no unknown
- 1982-02-10 SU SU823388657A patent/SU1069626A3/ru active
- 1982-02-10 JP JP57019012A patent/JPS57150685A/ja active Granted
- 1982-02-11 AR AR288400A patent/AR228385A1/es active
- 1982-02-11 GB GB8204017A patent/GB2096597B/en not_active Expired
 
Also Published As
| Publication number | Publication date | 
|---|---|
| BE892070A (fr) | 1982-08-09 | 
| AU8033982A (en) | 1982-08-19 | 
| NL8200493A (nl) | 1982-09-01 | 
| PT74402A (en) | 1982-03-01 | 
| ATA26282A (de) | 1986-07-15 | 
| CA1199637A (en) | 1986-01-21 | 
| DK57682A (da) | 1982-08-12 | 
| SE8200524L (sv) | 1982-08-12 | 
| JPS57150685A (en) | 1982-09-17 | 
| IT1157921B (it) | 1987-02-18 | 
| DE3204588C2 (OSRAM) | 1990-10-04 | 
| AU545745B2 (en) | 1985-08-01 | 
| FR2499573B1 (fr) | 1985-12-27 | 
| DD201593A5 (de) | 1983-07-27 | 
| DK151022C (da) | 1988-06-20 | 
| SU1069626A3 (ru) | 1984-01-23 | 
| IT8219588A0 (it) | 1982-02-10 | 
| DE3204588A1 (de) | 1982-12-30 | 
| DK151022B (da) | 1987-10-12 | 
| GB2096597B (en) | 1984-10-24 | 
| GB2096597A (en) | 1982-10-20 | 
| ES509418A0 (es) | 1983-08-01 | 
| GR75858B (OSRAM) | 1984-08-02 | 
| FI820364L (fi) | 1982-08-12 | 
| NO820395L (no) | 1982-08-12 | 
| HU183326B (en) | 1984-04-28 | 
| FR2499573A1 (fr) | 1982-08-13 | 
| FI70019C (fi) | 1986-09-12 | 
| US4432982A (en) | 1984-02-21 | 
| ES8307803A1 (es) | 1983-08-01 | 
| AT382375B (de) | 1987-02-25 | 
| FI70019B (fi) | 1986-01-31 | 
| PT74402B (en) | 1983-07-07 | 
| AR228385A1 (es) | 1983-02-28 | 
Similar Documents
| Publication | Publication Date | Title | 
|---|---|---|
| US4294822A (en) | 5-Aminoalkyl-4,4,8-trialkylpsoralens | |
| EP0601322A2 (en) | Adenosindeaminase inhibitor | |
| JPS6340167B2 (OSRAM) | ||
| EP0087378B1 (fr) | Ethers-oximes d'alcoylaminoalcools comme médicaments, produits nouveaux et procédés pour leur préparation | |
| EP1098891B1 (de) | Polycyclische thiazolidin-2-yliden amine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
| US6476059B1 (en) | Use of polycyclic 2-aminothiazole systems for the treatment of obesity | |
| US4328231A (en) | Method of treating psoriasis | |
| US4294847A (en) | 8-Aminoalkyl-4-alkylisopsoralens | |
| ZA200106198B (en) | Polycyclic 2-amino-thiazole systems, method for the production thereof and medicament containing said compounds. | |
| JPH0378393B2 (OSRAM) | ||
| KR20010103775A (ko) | 비만의 예방 또는 치료용 약제를 제조하기 위한폴리사이클릭 티아졸 시스템의 용도 | |
| JPS6341474A (ja) | 抗炎症剤 | |
| EP3008041B1 (en) | 3-carbamoyl-1-methylpyridinium nitrite, process for its preparation and its use | |
| EP0105458B1 (en) | Alpha-aryl-alpha-pyridylalkanoic acid derivatives, process for preparation thereof and pharmaceutical composition comprising the same | |
| KR20140123513A (ko) | 탄소환 뉴클레오시드 및 이들의 약학적 용도 및 조성물 | |
| LU81430A1 (fr) | Nouvelles cystamines | |
| SU1227115A3 (ru) | Способ получени 17,18-дегидро-аповинкаминол-3',4',5'-триметоксибензоата или его солей | |
| DE3650311T2 (de) | Verwendung von Quinazolinen zur Herstellung eines Arzneimittels zur Behandlung und Vorbeugung von Arrhythmie. | |
| JPS58502000A (ja) | 置換ピロ−ル | |
| JPH072741A (ja) | 2,2−ジハロ−1,4−ジアミノブタン化合物及び製薬上受入れられるその塩 | |
| US4424224A (en) | Apovincaminol derivative and compositions and methods utilizing it for treating psoriasis | |
| US4419359A (en) | Nitro-substituted polycyclic derivatives useful in the treatment of psoriasis | |
| US3801578A (en) | 7-(2-hydroxy-3-(n-methyl-2-hydroxy-ethylamino)-propyl)-theophylline-2-(4-chlorophenoxy)-isobutyrate | |
| EP0115789B1 (de) | Verwendung von "Nafazatrom" | |
| US3433789A (en) | S-benzoyloxymethyl-thiamines |