JPH0369910B2 - - Google Patents

Info

Publication number
JPH0369910B2
JPH0369910B2 JP54163965A JP16396579A JPH0369910B2 JP H0369910 B2 JPH0369910 B2 JP H0369910B2 JP 54163965 A JP54163965 A JP 54163965A JP 16396579 A JP16396579 A JP 16396579A JP H0369910 B2 JPH0369910 B2 JP H0369910B2
Authority
JP
Japan
Prior art keywords
formula
compound
compounds
residue
administered
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP54163965A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5583783A (en
Inventor
Noiman Peetaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of JPS5583783A publication Critical patent/JPS5583783A/ja
Publication of JPH0369910B2 publication Critical patent/JPH0369910B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
JP16396579A 1978-12-18 1979-12-17 1*44dihydropyridine derivative Granted JPS5583783A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1283578A CH639659A5 (de) 1978-12-18 1978-12-18 Neue 1,4-dihydropyridinderivate, deren herstellung und verwendung.

Publications (2)

Publication Number Publication Date
JPS5583783A JPS5583783A (en) 1980-06-24
JPH0369910B2 true JPH0369910B2 (fr) 1991-11-05

Family

ID=4386824

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16396579A Granted JPS5583783A (en) 1978-12-18 1979-12-17 1*44dihydropyridine derivative

Country Status (18)

Country Link
JP (1) JPS5583783A (fr)
AU (1) AU536055B2 (fr)
BE (1) BE880591A (fr)
CH (1) CH639659A5 (fr)
CY (1) CY1321A (fr)
DE (1) DE2949491A1 (fr)
FR (1) FR2444681A1 (fr)
GB (2) GB2103203B (fr)
HK (1) HK16086A (fr)
IE (1) IE49496B1 (fr)
IT (1) IT1164097B (fr)
KE (1) KE3593A (fr)
MY (1) MY8500130A (fr)
NL (2) NL193066C (fr)
NZ (1) NZ192422A (fr)
SE (1) SE445219B (fr)
SG (1) SG97585G (fr)
ZA (1) ZA796842B (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3022030A1 (de) * 1980-06-12 1981-12-17 Bayer Ag, 5090 Leverkusen 4-thiazol- bzw. 4-imidazol-substituierte, 1,4-dihydropyridine, verfahren zu deren herstellung sowie diese enthaltende arzneimittel
CH655658B (fr) * 1980-09-18 1986-05-15
EP0080220B1 (fr) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridines, leur procédé de préparation, leurs compositions et leur application comme médicaments
ZA83959B (en) * 1982-03-10 1984-09-26 Sandoz Ltd 1,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
US4414213A (en) * 1982-03-22 1983-11-08 Mead Johnson & Company Dihydropyridyl cyclic imidate esters and their pharmaceutical use
FR2528431B1 (fr) * 1982-06-15 1986-01-10 Sandoz Sa Nouveaux derives de la 1,4-dihydropyridine, leur preparation et leur utilisation comme medicaments
IL68975A (en) * 1982-06-15 1987-01-30 Sandoz Ag 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydropyridine-3,5-dicarboxylic acid ester derivatives in optically active form,their preparation and pharmaceutical compositions containing them
JPS5978186A (ja) * 1982-10-27 1984-05-04 Yoshitomi Pharmaceut Ind Ltd １，４−ジヒドロピリジン−３，５−ジカルボン酸エステル誘導体
US4794111A (en) * 1984-05-23 1988-12-27 Bayer Aktiengesellschaft Dihydropyridine preparations containing β-blockers
NL194389C (nl) * 1984-06-14 2002-03-04 Novartis Ag Werkwijze voor het bereiden van een vaste dispersie van een farmaceutisch actief middel dat een lage oplosbaarheid in water heeft, in een vaste matrix van een in water oplosbaar polyalkyleenglycol als drager.
US5260321A (en) * 1984-11-12 1993-11-09 Sandoz Ltd. Use of 1,4-dihydropyridine derivatives and combinations thereof with calcitonins
NL194822C (nl) * 1985-10-01 2003-04-03 Novartis Ag Preparaat voor orale toediening met geregelde afgifte en werkwijze voor de bereiding ervan.
DE3542794A1 (de) * 1985-12-04 1987-06-11 Bayer Ag Antihypertensives kombinationspraeparat
GB8626217D0 (en) * 1986-11-03 1986-12-03 Sandoz Ltd Pharmaceutical compositions
US4816263A (en) * 1987-10-02 1989-03-28 Alza Corporation Dosage form for treating cardiovascular diseases comprising isradipine
KR940003492B1 (ko) * 1988-10-27 1994-04-23 주식회사 유한양행 1,4-디하이드로피리딘유도체 및 그의 제조방법
DE4222770A1 (de) * 1992-07-10 1994-01-13 Bayer Ag Lichtaktivierbare 1-(2-Nitrobenzyl)-substituierte 1,4-Dihydropyridine
CN1649614A (zh) 2002-02-22 2005-08-03 新河药品股份有限公司 活性剂传递系统和保护及施用活性剂的方法
WO2005023787A1 (fr) * 2003-09-10 2005-03-17 Shasun Chemicals And Drugs Limited Procede d'elaboration de 2,1,3-benzoxadiazole-4-carboxaldehyde
CN103613584B (zh) * 2013-11-27 2016-04-27 沈阳药科大学 一种伊拉地平合成产物后处理的方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670824C3 (de) * 1967-03-20 1978-08-03 Bayer Ag, 5090 Leverkusen 1,4-Dihydropyridin-33-dicarbonsäurealkylester
FR2320750A1 (fr) * 1975-08-12 1977-03-11 Hexachimie Dihydro-1,4 pyridines et leur application therapeutique
DE2616991A1 (de) * 1976-04-17 1977-10-27 Bayer Ag Heterocyclisch-substituierte schwefelhaltige dihydropyridine, mehrere verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
FI64938C (fi) * 1977-06-20 1984-02-10 Sandoz Ag Foerfarande foer framstaellning av nya terapeutiskt anvaendbara bensoxa- och bensotiadiazolyl-1,4-dihydropyridinderivat

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5373327A (en) * 1976-12-13 1978-06-29 Matsushita Electric Ind Co Ltd Power source system

Also Published As

Publication number Publication date
AU536055B2 (en) 1984-04-19
IE792445L (en) 1980-06-18
FR2444681B1 (fr) 1982-10-29
HK16086A (en) 1986-03-14
SG97585G (en) 1986-07-18
IT1164097B (it) 1987-04-08
DE2949491C2 (fr) 1988-10-27
NL193066B (nl) 1998-05-06
SE7910188L (sv) 1980-06-19
KE3593A (en) 1986-02-07
FR2444681A1 (fr) 1980-07-18
GB2037766A (en) 1980-07-16
GB2037766B (en) 1983-02-16
GB2103203A (en) 1983-02-16
BE880591A (fr) 1980-06-13
CY1321A (en) 1986-06-27
NL7909024A (nl) 1980-06-20
SE445219B (sv) 1986-06-09
GB2103203B (en) 1983-06-08
ZA796842B (en) 1981-07-29
MY8500130A (en) 1985-12-31
IT7951095A0 (it) 1979-12-14
AU5389679A (en) 1980-06-26
NZ192422A (en) 1982-09-14
NL193066C (nl) 1998-09-08
CH639659A5 (de) 1983-11-30
NL990014I1 (nl) 1999-07-01
JPS5583783A (en) 1980-06-24
IE49496B1 (en) 1985-10-16
DE2949491A1 (de) 1980-06-26

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