JPH036124B2 - - Google Patents

Info

Publication number
JPH036124B2
JPH036124B2 JP55029471A JP2947180A JPH036124B2 JP H036124 B2 JPH036124 B2 JP H036124B2 JP 55029471 A JP55029471 A JP 55029471A JP 2947180 A JP2947180 A JP 2947180A JP H036124 B2 JPH036124 B2 JP H036124B2
Authority
JP
Japan
Prior art keywords
radioactive
labeled
physiologically active
gallium
solution
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP55029471A
Other languages
English (en)
Japanese (ja)
Other versions
JPS56125317A (en
Inventor
Akira Yokoyama
Yoshiaki Oomomo
Hisashi Tanaka
Hideo Saji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon Medi Physics Co Ltd
Original Assignee
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Medi Physics Co Ltd filed Critical Nihon Medi Physics Co Ltd
Priority to JP2947180A priority Critical patent/JPS56125317A/ja
Priority to US06/236,520 priority patent/US4425319A/en
Priority to AU67935/81A priority patent/AU537814B2/en
Priority to CA000372371A priority patent/CA1165686A/en
Priority to DE8181101612T priority patent/DE3167264D1/de
Priority to EP81101612A priority patent/EP0035765B1/en
Publication of JPS56125317A publication Critical patent/JPS56125317A/ja
Publication of JPH036124B2 publication Critical patent/JPH036124B2/ja
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2947180A 1980-03-08 1980-03-08 Stable radioactive diagnosticum with radioactive metallic mark Granted JPS56125317A (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
JP2947180A JPS56125317A (en) 1980-03-08 1980-03-08 Stable radioactive diagnosticum with radioactive metallic mark
US06/236,520 US4425319A (en) 1980-03-08 1981-02-20 Radioactive diagnostic agent and non-radioactive carrier therefor
AU67935/81A AU537814B2 (en) 1980-03-08 1981-02-27 Radioactive diagnostic agent
CA000372371A CA1165686A (en) 1980-03-08 1981-03-05 Radioactive diagnostic agent and non-radioactive carrier therefor
DE8181101612T DE3167264D1 (en) 1980-03-08 1981-03-06 A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound
EP81101612A EP0035765B1 (en) 1980-03-08 1981-03-06 A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2947180A JPS56125317A (en) 1980-03-08 1980-03-08 Stable radioactive diagnosticum with radioactive metallic mark

Publications (2)

Publication Number Publication Date
JPS56125317A JPS56125317A (en) 1981-10-01
JPH036124B2 true JPH036124B2 (en, 2012) 1991-01-29

Family

ID=12277007

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2947180A Granted JPS56125317A (en) 1980-03-08 1980-03-08 Stable radioactive diagnosticum with radioactive metallic mark

Country Status (6)

Country Link
US (1) US4425319A (en, 2012)
EP (1) EP0035765B1 (en, 2012)
JP (1) JPS56125317A (en, 2012)
AU (1) AU537814B2 (en, 2012)
CA (1) CA1165686A (en, 2012)
DE (1) DE3167264D1 (en, 2012)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4479930A (en) * 1982-07-26 1984-10-30 Trustees Of The University Of Massachusetts Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product
US4666697A (en) * 1982-12-08 1987-05-19 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic agent
JPS59134732A (ja) * 1983-01-21 1984-08-02 Green Cross Corp:The フイブロネクチン・生理活性物質複合体の製造法
JPS59199636A (ja) * 1983-04-26 1984-11-12 Nippon Mejifuijitsukusu Kk 放射性診断剤
US4556068A (en) * 1983-08-26 1985-12-03 The United States Of America As Represented By The Department Of Energy In-vivo measurement of lithium in the brain and other organs
US4732864A (en) * 1983-10-06 1988-03-22 E. I. Du Pont De Nemours And Company Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
EP0170031A1 (de) * 1984-07-04 1986-02-05 Gesellschaft zur Förderung der industrieorientierten Forschung an den Schweizerischen Hochschulen und weiteren Institutionen Radioaktives Diagnosemittel zum Nachweisen einer venösen Thrombose
US5089644A (en) * 1985-01-04 1992-02-18 Salutar Inc. Preparation of oxamine complexes
US5217998A (en) * 1985-07-02 1993-06-08 Biomedical Frontiers, Inc. Composition for the stabilization of deferoxamine to chelate free ions in physiological fluid
US4863964A (en) * 1985-07-02 1989-09-05 Biomedical Frontiers, Inc. Method for the stabilization of deferoxamine to chelate free ions in physiological fluid
DK172629B1 (da) * 1986-02-14 1999-03-22 Nihon Mediphysics Co Ltd Reaktive højmolekylære forbindelser med mindst én fri aminogruppe, højmolekylære forbindelser kombineret med et fysiologisk
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
CA1335725C (en) * 1987-09-25 1995-05-30 Stephen W. Hadley Method of diagnosing blood clots using fibrin-binding proteins
US5217705A (en) * 1987-09-25 1993-06-08 Neorx Corporation Method of diagnosing blood clots using fibrin-binding proteins
US5268165A (en) * 1990-10-16 1993-12-07 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
AU8950291A (en) * 1990-10-16 1992-05-20 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
JP3051591B2 (ja) * 1993-03-05 2000-06-12 日本メジフィジックス株式会社 タリウム−２０１の容器に対する付着防止剤
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
AU2003299590B8 (en) * 2002-12-09 2010-04-08 Abraxis Bioscience, Llc Compositions and methods of delivery of pharmacological agents
BR0317134A (pt) * 2002-12-09 2005-11-22 American Bioscience Inc Composições e métodos de liberação de agentes farmacológicos
CN1925874B (zh) * 2002-12-09 2014-12-17 阿布拉西斯生物科学有限责任公司 组合物和传递药剂的方法
US11197938B1 (en) * 2016-10-19 2021-12-14 Battelle Memorial Institute System and process for production of isotopes and isotope compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL42204A (en) * 1972-05-08 1976-09-30 Solco Basel Ag Process and apparatus for the manufacture of injectable radionuclide preparations
JPS5266636A (en) * 1975-12-01 1977-06-02 Union Carbide Corp Technetiumm99m labelled radiation diagnostic agent and method of making same
JPS5283961A (en) * 1976-01-01 1977-07-13 Pharmacia Fine Chemicals Ab Medicine for administrating in blood

Also Published As

Publication number Publication date
EP0035765A2 (en) 1981-09-16
JPS56125317A (en) 1981-10-01
DE3167264D1 (en) 1985-01-03
EP0035765A3 (en) 1982-03-17
AU6793581A (en) 1981-09-17
CA1165686A (en) 1984-04-17
AU537814B2 (en) 1984-07-12
US4425319A (en) 1984-01-10
EP0035765B1 (en) 1984-11-21

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