DE3167264D1 - A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound - Google Patents

A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound

Info

Publication number
DE3167264D1
DE3167264D1 DE8181101612T DE3167264T DE3167264D1 DE 3167264 D1 DE3167264 D1 DE 3167264D1 DE 8181101612 T DE8181101612 T DE 8181101612T DE 3167264 T DE3167264 T DE 3167264T DE 3167264 D1 DE3167264 D1 DE 3167264D1
Authority
DE
Germany
Prior art keywords
compound
preparation
active substance
physiologically active
metallic element
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8181101612T
Other languages
English (en)
Inventor
Akira Yokoyama
Yoshiro C O Mr Soichiro Omomo
Hisashi Tanaka
Hideo C O Mr Hiromitsu Ki Saji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nihon Medi Physics Co Ltd
Original Assignee
Nihon Medi Physics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Medi Physics Co Ltd filed Critical Nihon Medi Physics Co Ltd
Application granted granted Critical
Publication of DE3167264D1 publication Critical patent/DE3167264D1/de
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE8181101612T 1980-03-08 1981-03-06 A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound Expired DE3167264D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2947180A JPS56125317A (en) 1980-03-08 1980-03-08 Stable radioactive diagnosticum with radioactive metallic mark

Publications (1)

Publication Number Publication Date
DE3167264D1 true DE3167264D1 (en) 1985-01-03

Family

ID=12277007

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8181101612T Expired DE3167264D1 (en) 1980-03-08 1981-03-06 A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound

Country Status (6)

Country Link
US (1) US4425319A (de)
EP (1) EP0035765B1 (de)
JP (1) JPS56125317A (de)
AU (1) AU537814B2 (de)
CA (1) CA1165686A (de)
DE (1) DE3167264D1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1222691A (en) * 1981-12-29 1987-06-09 Wilhelmus T. Goedemans Method of preparing radionuclide-labelled proteins, in particular antibodies or antibody fragments
US4479930A (en) * 1982-07-26 1984-10-30 Trustees Of The University Of Massachusetts Amines coupled wth dicyclic dianhydrides capable of being radiolabeled product
US4666697A (en) * 1982-12-08 1987-05-19 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic agent
JPS59134732A (ja) * 1983-01-21 1984-08-02 Green Cross Corp:The フイブロネクチン・生理活性物質複合体の製造法
JPS59199636A (ja) * 1983-04-26 1984-11-12 Nippon Mejifuijitsukusu Kk 放射性診断剤
US4556068A (en) * 1983-08-26 1985-12-03 The United States Of America As Represented By The Department Of Energy In-vivo measurement of lithium in the brain and other organs
US4732864A (en) * 1983-10-06 1988-03-22 E. I. Du Pont De Nemours And Company Trace-labeled conjugates of metallothionein and target-seeking biologically active molecules
EP0170031A1 (de) * 1984-07-04 1986-02-05 Gesellschaft zur Förderung der industrieorientierten Forschung an den Schweizerischen Hochschulen und weiteren Institutionen Radioaktives Diagnosemittel zum Nachweisen einer venösen Thrombose
US5089644A (en) * 1985-01-04 1992-02-18 Salutar Inc. Preparation of oxamine complexes
US5217998A (en) * 1985-07-02 1993-06-08 Biomedical Frontiers, Inc. Composition for the stabilization of deferoxamine to chelate free ions in physiological fluid
US4863964A (en) * 1985-07-02 1989-09-05 Biomedical Frontiers, Inc. Method for the stabilization of deferoxamine to chelate free ions in physiological fluid
CA1266344A (en) * 1986-02-14 1990-02-27 Miki Kurami High molecular compounds having amino groups, and their utilization
US5707604A (en) * 1986-11-18 1998-01-13 Access Pharmaceuticals, Inc. Vivo agents comprising metal-ion chelates with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
WO1989002752A1 (en) * 1987-09-25 1989-04-06 Genentech, Inc. Method of diagnosing blood clots using fibrin-binding proteins
US5217705A (en) * 1987-09-25 1993-06-08 Neorx Corporation Method of diagnosing blood clots using fibrin-binding proteins
US5268165A (en) * 1990-10-16 1993-12-07 Biomedical Frontiers, Inc. Polymer-deferoxamine-ferric iron adducts for use in magnetic resonance imaging
JPH06502177A (ja) * 1990-10-16 1994-03-10 バイオメディカル・フロンティアーズ・インコーポレイテッド 磁気共鳴映像用ポリマー−デフェロキサミン−第２鉄付加物
JP3051591B2 (ja) * 1993-03-05 2000-06-12 日本メジフィジックス株式会社 タリウム−２０１の容器に対する付着防止剤
US6106866A (en) * 1995-07-31 2000-08-22 Access Pharmaceuticals, Inc. In vivo agents comprising cationic drugs, peptides and metal chelators with acidic saccharides and glycosaminoglycans, giving improved site-selective localization, uptake mechanism, sensitivity and kinetic-spatial profiles, including tumor sites
WO2004052401A2 (en) * 2002-12-09 2004-06-24 American Bioscience, Inc. Compositions and methods of delivery of pharmacological agents
CN1925874B (zh) * 2002-12-09 2014-12-17 阿布拉西斯生物科学有限责任公司 组合物和传递药剂的方法
US20050004002A1 (en) 2002-12-09 2005-01-06 American Bioscience, Inc. Compositions and methods of delivery of pharmacological agents

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU167378B (de) * 1972-05-08 1975-09-27
NL7613339A (nl) * 1975-12-01 1977-06-03 Union Carbide Corp Radiodiagnostische middelen.
JPS5283961A (en) * 1976-01-01 1977-07-13 Pharmacia Fine Chemicals Ab Medicine for administrating in blood

Also Published As

Publication number Publication date
EP0035765B1 (de) 1984-11-21
US4425319A (en) 1984-01-10
EP0035765A2 (de) 1981-09-16
CA1165686A (en) 1984-04-17
AU537814B2 (en) 1984-07-12
AU6793581A (en) 1981-09-17
JPH036124B2 (de) 1991-01-29
JPS56125317A (en) 1981-10-01
EP0035765A3 (en) 1982-03-17

Similar Documents

Publication Publication Date Title
DE3167264D1 (en) A physiologically active substance-combined compound and its use for the preparation of a radioactive metallic element-labeled compound
IL64160A0 (en) Powdered medicament
EP0072251A3 (en) Improved bandage containing a medicament
PT72914B (en) Beta-lactam compounds their preparation and use
GB2110543B (en) Inhalers
JPS57118794A (en) Imunosome and preparation thereof
JPS545000A (en) Phosdhorusscontaining polyaddition compound and preparation thereof
DE3380062D1 (en) Polyprenyl compound and drug containing the same
JPS5522951A (en) Compound tube and its preparation
ZW8781A1 (en) 2-nitroimidazoles and preparation thereof
ZA817796B (en) Use of anticholenergic drugs
JPS5550934A (en) Compound metallic plate and its preparation
DE3174163D1 (en) Pharmaceutically active compounds
DE3171920D1 (en) Radioactive diagnostic agent and its preparation
GB2071549B (en) Welded can and its preparation
GB2119365B (en) Preparation of azinomethyl-rifamycins
EP0041801A3 (en) A capsule of grouting material and methods for the preparation and use thereof
GB2103564B (en) Compound capsule
ZA81114B (en) Prostanoid compounds and their preparation and pharmaceutical formalation
JPS57142986A (en) Medicinally active compound
JPS5513284A (en) Imidazoline compound and medical composition
IL64156A (en) Decapeptide compounds and their preparation
JPS55105642A (en) Chlorobenzylphenoxyalkoxyl compound and its manufacture
DE3360234D1 (en) Polyprenyl compounds and preparation thereof
ZA81523B (en) Compound with a psychostimulant and antidepressive activity process for its preparation and related pharmaceutical compositions

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee