JPH03502200A - クロマトグラフィーによる高純度の非感染性抗血友病因子の生産方法 - Google Patents

クロマトグラフィーによる高純度の非感染性抗血友病因子の生産方法

Info

Publication number
JPH03502200A
JPH03502200A JP2500028A JP50002890A JPH03502200A JP H03502200 A JPH03502200 A JP H03502200A JP 2500028 A JP2500028 A JP 2500028A JP 50002890 A JP50002890 A JP 50002890A JP H03502200 A JPH03502200 A JP H03502200A
Authority
JP
Japan
Prior art keywords
chromatography
factor viii
plasma
gel permeation
column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2500028A
Other languages
English (en)
Japanese (ja)
Inventor
スミス、アンドリュー
Original Assignee
オクタファルマ・アー・ゲー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8199529&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=JPH03502200(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by オクタファルマ・アー・ゲー filed Critical オクタファルマ・アー・ゲー
Publication of JPH03502200A publication Critical patent/JPH03502200A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Chemical Vapour Deposition (AREA)
  • Intermediate Stations On Conveyors (AREA)
JP2500028A 1988-11-05 1989-10-19 クロマトグラフィーによる高純度の非感染性抗血友病因子の生産方法 Pending JPH03502200A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88118478.2 1988-11-05
EP88118478A EP0367840B1 (fr) 1988-11-05 1988-11-05 Procédé de préparation d'un facteur antihémophilique non infectieux et de grande pureté par chromatographie

Publications (1)

Publication Number Publication Date
JPH03502200A true JPH03502200A (ja) 1991-05-23

Family

ID=8199529

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2500028A Pending JPH03502200A (ja) 1988-11-05 1989-10-19 クロマトグラフィーによる高純度の非感染性抗血友病因子の生産方法

Country Status (8)

Country Link
EP (1) EP0367840B1 (fr)
JP (1) JPH03502200A (fr)
AT (1) ATE85221T1 (fr)
DE (1) DE3878245D1 (fr)
DK (1) DK161590A (fr)
ES (1) ES2053684T3 (fr)
FI (1) FI903366A0 (fr)
WO (1) WO1990005140A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH069694A (ja) * 1992-04-24 1994-01-18 Immuno Ag 因子ｖｉｉｉ製品の製造方法
JPH08506498A (ja) * 1993-02-09 1996-07-16 オクタファルマ・アクチエンゲセルシャフト 非脂質被覆ウイルスの失活方法

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4008852A1 (de) * 1990-03-20 1991-09-26 Octapharma Ag Verfahren zur herstellung von nicht-infektioesem blutplasma
IT1248723B (it) * 1990-06-12 1995-01-26 Scalvo S P A Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo
FR2681867B1 (fr) * 1991-09-26 1993-12-31 Pasteur Merieux Serums Vaccins Procede de purification du facteur viii et preparations obtenues.
DE4204694C3 (de) * 1992-02-01 1995-10-12 Octapharma Ag Verfahren zur Gewinnung von hochreinem, virusinaktiviertem Faktor VIII mittels Anionenaustauscher-Chromatographie
IT1256622B (it) * 1992-12-04 1995-12-12 Sclavo Spa Processo per l'estrazione del complesso fattore viii-fattore von willebrand (fviii:c-fvw) da plasma umano totale.
SE9301582D0 (sv) * 1993-05-07 1993-05-07 Kabi Pharmacia Ab Purification of plasma proteins
DE4337573C1 (de) * 1993-11-04 1995-05-18 Octapharma Ag Verfahren zur Herstellung einer virusinaktivierten Faktor VIII enthaltenden Fraktion mittels chromatographischer Methoden
AT407159B (de) † 1997-06-13 2001-01-25 Immuno Ag Verfahren zur abreicherung von viralen und molekularen pathogenen aus einem biologischen material
WO2000074733A1 (fr) * 1999-06-08 2000-12-14 Octapharma Ag Procede d'elimination de virus d'echantillons biologiques
EP1148063A1 (fr) 2000-04-18 2001-10-24 Octapharma AG Composition contenant du vWF (facteur von Willebrand) hémostatique actif et procédé pour sa préparation

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE713764A (fr) 1967-05-01 1968-09-16 Baxter Travenol Lab
JPS52125609A (en) 1976-04-09 1977-10-21 Green Cross Corp:The Purification of agglutination factor viii
DE2635894A1 (de) * 1976-08-10 1978-02-16 Biotest Serum Institut Gmbh Verfahren zur herstellung eines antihaemophiles globulin a enthaltenden konzentrats
US4386068A (en) * 1980-02-26 1983-05-31 Cutter Laboratories, Inc. Antihemophilic factor concentrate and method for preparation
US4495175A (en) 1982-08-05 1985-01-22 University Of Rochester Preparation of highly purified human antihemophilic factor
US4540573A (en) 1983-07-14 1985-09-10 New York Blood Center, Inc. Undenatured virus-free biologically active protein derivatives
US4478825A (en) * 1983-10-14 1984-10-23 Armour Pharmaceutical Company Warm ethanol method for preparation of low fibrinogen antihemophilic factor
US4508709A (en) * 1983-12-05 1985-04-02 Armour Pharmaceutical Company Process for purifying factor VIII:C
DE3432083A1 (de) 1984-08-31 1986-03-06 Behringwerke Ag, 3550 Marburg Pasteurisierte, isoagglutininfreie faktor viii-praeparation und verfahren zu ihrer herstellung
US4743680A (en) 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
EP0238701B1 (fr) * 1986-03-27 1992-03-18 Octapharma AG Procédé de production d'un facteur anti-hémophilique hautement purifié
US4789545A (en) 1986-03-31 1988-12-06 New York Blood Center, Inc. Removal of lipid soluble process chemicals from biological materials by extraction with naturally occurring oils or synthetic substitutes thereof
JPS63108000A (ja) * 1986-05-15 1988-05-12 Green Cross Corp:The 第８因子の精製方法
EP0343275B1 (fr) 1988-05-27 1993-02-03 Centre Regional De Transfusion Sanguine De Lille Procédé de préparation d'un facteur antihémophilique hautement purifié exempt de virus au moyen de chromatographie

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH069694A (ja) * 1992-04-24 1994-01-18 Immuno Ag 因子ｖｉｉｉ製品の製造方法
JPH08506498A (ja) * 1993-02-09 1996-07-16 オクタファルマ・アクチエンゲセルシャフト 非脂質被覆ウイルスの失活方法

Also Published As

Publication number Publication date
DK161590D0 (da) 1990-07-04
FI903366A0 (fi) 1990-07-04
EP0367840A1 (fr) 1990-05-16
WO1990005140A1 (fr) 1990-05-17
DE3878245D1 (de) 1993-03-18
ES2053684T3 (es) 1994-08-01
DK161590A (da) 1990-07-04
ATE85221T1 (de) 1993-02-15
EP0367840B1 (fr) 1993-02-03

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