JPH0310343B2 - - Google Patents

Info

Publication number

JPH0310343B2

JPH0310343B2 JP58067950A JP6795083A JPH0310343B2 JP H0310343 B2 JPH0310343 B2 JP H0310343B2 JP 58067950 A JP58067950 A JP 58067950A JP 6795083 A JP6795083 A JP 6795083A JP H0310343 B2 JPH0310343 B2 JP H0310343B2

Authority

JP

Japan

Prior art keywords

sterilization

membrane

ray irradiation

gamma ray

sterilizing

Prior art date

1983-04-18

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Expired - Lifetime

Links

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• 239000012528 membrane Substances 0.000 claims description 24
• 230000001954 sterilising effect Effects 0.000 claims description 20
• 238000000034 method Methods 0.000 claims description 13
• 230000008595 infiltration Effects 0.000 claims description 10
• 238000001764 infiltration Methods 0.000 claims description 10
• 239000011261 inert gas Substances 0.000 claims description 9
• 229920002301 cellulose acetate Polymers 0.000 claims description 4
• IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
• CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims 2
• 229910002092 carbon dioxide Inorganic materials 0.000 claims 1
• 239000001569 carbon dioxide Substances 0.000 claims 1
• 230000001678 irradiating effect Effects 0.000 claims 1
• 229910052757 nitrogen Inorganic materials 0.000 claims 1
• 238000004659 sterilization and disinfection Methods 0.000 description 14
• 230000005251 gamma ray Effects 0.000 description 12
• 239000000463 material Substances 0.000 description 10
• 239000007789 gas Substances 0.000 description 6
• 241000894006 Bacteria Species 0.000 description 5
• 230000006866 deterioration Effects 0.000 description 4
• 210000003734 kidney Anatomy 0.000 description 4
• 238000000502 dialysis Methods 0.000 description 3
• 230000000694 effects Effects 0.000 description 3
• 238000012360 testing method Methods 0.000 description 3
• WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 2
• XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 2
• 239000008280 blood Substances 0.000 description 2
• 210000004369 blood Anatomy 0.000 description 2
• 229920002678 cellulose Polymers 0.000 description 2
• 239000001913 cellulose Substances 0.000 description 2
• DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 2
• 239000007788 liquid Substances 0.000 description 2
• 230000001590 oxidative effect Effects 0.000 description 2
• 238000004806 packaging method and process Methods 0.000 description 2
• -1 polyethylene Polymers 0.000 description 2
• 238000004321 preservation Methods 0.000 description 2
• 238000011160 research Methods 0.000 description 2
• 238000010998 test method Methods 0.000 description 2
• 229920001747 Cellulose diacetate Polymers 0.000 description 1
• 229920002284 Cellulose triacetate Polymers 0.000 description 1
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
• IAYPIBMASNFSPL-UHFFFAOYSA-N Ethylene oxide Chemical compound C1CO1 IAYPIBMASNFSPL-UHFFFAOYSA-N 0.000 description 1
• 239000004698 Polyethylene Substances 0.000 description 1
• 239000004743 Polypropylene Substances 0.000 description 1
• NNLVGZFZQQXQNW-ADJNRHBOSA-N [(2r,3r,4s,5r,6s)-4,5-diacetyloxy-3-[(2s,3r,4s,5r,6r)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-6-[(2r,3r,4s,5r,6s)-4,5,6-triacetyloxy-2-(acetyloxymethyl)oxan-3-yl]oxyoxan-2-yl]methyl acetate Chemical compound O([C@@H]1O[C@@H]([C@H]([C@H](OC(C)=O)[C@H]1OC(C)=O)O[C@H]1[C@@H]([C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](COC(C)=O)O1)OC(C)=O)COC(=O)C)[C@@H]1[C@@H](COC(C)=O)O[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O NNLVGZFZQQXQNW-ADJNRHBOSA-N 0.000 description 1
• 238000000862 absorption spectrum Methods 0.000 description 1
• 230000001580 bacterial effect Effects 0.000 description 1
• 210000001124 body fluid Anatomy 0.000 description 1
• 239000010839 body fluid Substances 0.000 description 1
• 239000004202 carbamide Substances 0.000 description 1
• FDJOLVPMNUYSCM-UVKKECPRSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2,7, Chemical compound [Co+3].N#[C-].C1([C@H](CC(N)=O)[C@@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)[N-]\C2=C(C)/C([C@H](C\2(C)C)CCC(N)=O)=N/C/2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O FDJOLVPMNUYSCM-UVKKECPRSA-L 0.000 description 1
• 229920001577 copolymer Polymers 0.000 description 1
• 229940109239 creatinine Drugs 0.000 description 1
• 230000002542 deteriorative effect Effects 0.000 description 1
• 238000005259 measurement Methods 0.000 description 1
• 230000002503 metabolic effect Effects 0.000 description 1
• 230000003647 oxidation Effects 0.000 description 1
• 238000007254 oxidation reaction Methods 0.000 description 1
• 230000035515 penetration Effects 0.000 description 1
• 229920003023 plastic Polymers 0.000 description 1
• 239000004033 plastic Substances 0.000 description 1
• 229920003229 poly(methyl methacrylate) Polymers 0.000 description 1
• 229920002492 poly(sulfone) Polymers 0.000 description 1
• 229920002239 polyacrylonitrile Polymers 0.000 description 1
• 229920000573 polyethylene Polymers 0.000 description 1
• 239000004926 polymethyl methacrylate Substances 0.000 description 1
• 229920001155 polypropylene Polymers 0.000 description 1
• 229920002635 polyurethane Polymers 0.000 description 1
• 239000004814 polyurethane Substances 0.000 description 1
• 238000012545 processing Methods 0.000 description 1
• 238000000746 purification Methods 0.000 description 1
• 230000001698 pyrogenic effect Effects 0.000 description 1
• 238000001223 reverse osmosis Methods 0.000 description 1
• 229920006395 saturated elastomer Polymers 0.000 description 1
• 238000000926 separation method Methods 0.000 description 1
• 239000000126 substance Substances 0.000 description 1
• 229940045136 urea Drugs 0.000 description 1
• 229920002554 vinyl polymer Polymers 0.000 description 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1