JPH0279981A - 成長因子活性を有する新規なポリペプチド及び該ポリペプチドをコードする核酸配列 - Google Patents
成長因子活性を有する新規なポリペプチド及び該ポリペプチドをコードする核酸配列Info
- Publication number
- JPH0279981A JPH0279981A JP1073723A JP7372389A JPH0279981A JP H0279981 A JPH0279981 A JP H0279981A JP 1073723 A JP1073723 A JP 1073723A JP 7372389 A JP7372389 A JP 7372389A JP H0279981 A JPH0279981 A JP H0279981A
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- Japan
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- amino acids
- sequence
- polypeptide
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- amino acid
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- Pending
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/485—Epidermal growth factor [EGF], i.e. urogastrone
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
- C12N15/625—DNA sequences coding for fusion proteins containing a sequence coding for a signal sequence
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
- C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
- C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/24011—Poxviridae
- C12N2710/24111—Orthopoxvirus, e.g. vaccinia virus, variola
- C12N2710/24122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Biotechnology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Toxicology (AREA)
- Animal Behavior & Ethology (AREA)
- Plant Pathology (AREA)
- Urology & Nephrology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Virology (AREA)
- Dermatology (AREA)
- Food Science & Technology (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17265388A | 1988-03-24 | 1988-03-24 | |
| US172653 | 1993-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPH0279981A true JPH0279981A (ja) | 1990-03-20 |
Family
ID=22628611
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP1073723A Pending JPH0279981A (ja) | 1988-03-24 | 1989-03-24 | 成長因子活性を有する新規なポリペプチド及び該ポリペプチドをコードする核酸配列 |
Country Status (22)
| Country | Link |
|---|---|
| JP (1) | JPH0279981A (es) |
| KR (1) | KR890014743A (es) |
| AU (2) | AU3169589A (es) |
| BE (1) | BE1004202A5 (es) |
| CH (1) | CH681081A5 (es) |
| DE (1) | DE3910084A1 (es) |
| DK (1) | DK146789A (es) |
| ES (1) | ES2013408A6 (es) |
| FI (1) | FI891308A (es) |
| FR (1) | FR2632321A1 (es) |
| GB (1) | GB2219799B (es) |
| GR (1) | GR1000876B (es) |
| HU (1) | HUT50501A (es) |
| IE (1) | IE890950L (es) |
| IL (1) | IL89673A0 (es) |
| IT (1) | IT1234961B (es) |
| LU (1) | LU87489A1 (es) |
| NL (1) | NL8900724A (es) |
| NO (1) | NO891273D0 (es) |
| NZ (1) | NZ228427A (es) |
| PT (1) | PT90118B (es) |
| SE (1) | SE8901031L (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0293785A3 (en) * | 1987-05-29 | 1990-05-02 | Oncogen Limited Partnership | Cloning and expression of simian transforming growth factor-ss1 |
| EP0444961A1 (en) * | 1990-03-02 | 1991-09-04 | Bristol-Myers Squibb Company | Her3: A novel EGF receptor homolog |
| EP0739984A1 (en) * | 1995-04-26 | 1996-10-30 | San Tumorforschungs-Gmbh | Bivalent polypeptides containing at least two domains |
| US6852506B1 (en) | 1996-04-10 | 2005-02-08 | Human Genome Sciences, Inc. | Extracellular/epidermal growth factor-like protein |
| AU5549296A (en) * | 1996-04-10 | 1997-10-29 | Human Genome Sciences, Inc. | Extracellular/epidermal growth factor-like protein |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1983004030A1 (en) * | 1982-05-06 | 1983-11-24 | Applied Molecular Genetics, Inc. | The manufacture and expression of genes for urogastrone and polypeptide analogs thereof |
| JPS6028994A (ja) * | 1983-07-08 | 1985-02-14 | Wakunaga Seiyaku Kk | 〔２１―ロイシン〕ヒトウロガストロン |
| WO1985002198A1 (en) * | 1983-11-01 | 1985-05-23 | Amgen | Microbial expression of type i transforming growth factor, polypeptide analogs thereof and hybrid egf/tgf polypeptides |
| JP2554459B2 (ja) * | 1984-07-02 | 1996-11-13 | アース製薬 株式会社 | β−ウロガストロン遺伝子、対応プラスミド組換体及び対応形質転換体 |
| WO1986002650A1 (en) * | 1984-10-30 | 1986-05-09 | Oncogen | Novel polypeptides having growth factor activity and nucleic acid sequences encoding the polypeptides |
| GB8507666D0 (en) * | 1985-03-25 | 1985-05-01 | Wellcome Found | Epidermal growth factor production |
| US4743679A (en) * | 1986-02-24 | 1988-05-10 | Creative Biomolecules, Inc. | Process for producing human epidermal growth factor and analogs thereof |
| GB2210618B (en) * | 1987-10-08 | 1991-10-16 | British Bio Technology | Synthetic egf gene |
| WO1989003886A1 (en) * | 1987-10-30 | 1989-05-05 | Oncogen, A Limited Partnership | Expression systems for preparation of polypeptides in prokaryotic cells |
| EP0314184B1 (en) * | 1987-10-30 | 1995-12-13 | Bristol-Myers Squibb Company | Expression plasmids |
-
1989
- 1989-03-20 IL IL89673A patent/IL89673A0/xx unknown
- 1989-03-20 FI FI891308A patent/FI891308A/fi not_active IP Right Cessation
- 1989-03-21 NZ NZ228427A patent/NZ228427A/xx unknown
- 1989-03-22 SE SE8901031A patent/SE8901031L/xx not_active Application Discontinuation
- 1989-03-22 DK DK146789A patent/DK146789A/da not_active Application Discontinuation
- 1989-03-22 NO NO891273A patent/NO891273D0/no unknown
- 1989-03-22 ES ES8901049A patent/ES2013408A6/es not_active Expired - Lifetime
- 1989-03-23 GR GR890100185A patent/GR1000876B/el unknown
- 1989-03-23 GB GB8906758A patent/GB2219799B/en not_active Expired - Fee Related
- 1989-03-23 NL NL8900724A patent/NL8900724A/nl not_active Application Discontinuation
- 1989-03-23 IE IE890950A patent/IE890950L/xx unknown
- 1989-03-23 AU AU31695/89A patent/AU3169589A/en not_active Abandoned
- 1989-03-24 HU HU891515A patent/HUT50501A/hu unknown
- 1989-03-24 IT IT8919917A patent/IT1234961B/it active
- 1989-03-24 LU LU87489A patent/LU87489A1/xx unknown
- 1989-03-24 FR FR8903952A patent/FR2632321A1/fr not_active Withdrawn
- 1989-03-24 JP JP1073723A patent/JPH0279981A/ja active Pending
- 1989-03-24 BE BE8900329A patent/BE1004202A5/fr not_active IP Right Cessation
- 1989-03-24 KR KR1019890003761A patent/KR890014743A/ko not_active Application Discontinuation
- 1989-03-27 PT PT90118A patent/PT90118B/pt active IP Right Grant
- 1989-03-28 CH CH1114/89A patent/CH681081A5/de not_active IP Right Cessation
- 1989-03-28 DE DE3910084A patent/DE3910084A1/de not_active Withdrawn
-
1992
- 1992-12-04 AU AU29904/92A patent/AU2990492A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IE890950L (en) | 1989-09-24 |
| AU2990492A (en) | 1993-03-04 |
| PT90118B (pt) | 1994-07-29 |
| HUT50501A (en) | 1990-02-28 |
| SE8901031L (sv) | 1989-09-25 |
| AU3169589A (en) | 1989-09-28 |
| BE1004202A5 (fr) | 1992-10-13 |
| DE3910084A1 (de) | 1989-11-16 |
| GR890100185A (en) | 1990-01-19 |
| NL8900724A (nl) | 1989-10-16 |
| ES2013408A6 (es) | 1990-05-01 |
| FR2632321A1 (fr) | 1989-12-08 |
| FI891308A0 (fi) | 1989-03-20 |
| DK146789D0 (da) | 1989-03-22 |
| KR890014743A (ko) | 1989-10-25 |
| IT8919917A0 (it) | 1989-03-24 |
| NO891273D0 (no) | 1989-03-22 |
| GB2219799A (en) | 1989-12-20 |
| NZ228427A (en) | 1993-03-26 |
| SE8901031D0 (sv) | 1989-03-22 |
| DK146789A (da) | 1989-09-25 |
| CH681081A5 (es) | 1993-01-15 |
| GR1000876B (el) | 1993-03-16 |
| GB8906758D0 (en) | 1989-05-10 |
| IT1234961B (it) | 1992-06-09 |
| IL89673A0 (en) | 1989-09-28 |
| LU87489A1 (fr) | 1989-10-26 |
| PT90118A (pt) | 1989-11-10 |
| FI891308A (fi) | 1989-09-25 |
| GB2219799B (en) | 1992-10-14 |
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